Division of Labor with a Workforce of One: Challenges in Specifying Effector and Memory T Cell Fate

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

1999 • 5,659 citations

The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells

2006 • 4,815 citations

Reciprocal T _H 17 and Regulatory T Cell Differentiation Mediated by Retinoic Acid

2007 • 1,890 citations

The lineage decisions of helper T cells

2002 • 1,678 citations

Inducing and expanding regulatory T cell populations by foreign antigen

2005 • 1,245 citations

Helper T Cell Differentiation Is Controlled by the Cell Cycle

1998 • 862 citations

Asymmetric T Lymphocyte Division in the Initiation of Adaptive Immune Responses

2007 • 824 citations

Differentiation and function of Th17 T cells

2007 • 720 citations

TH1 cells control themselves by producing interleukin-10

2007 • 599 citations

Follicular B helper T cells in antibody responses and autoimmunity

2005 • 592 citations

T cell fitness determined by signal strength

2003 • 478 citations

Initial T Cell Receptor Transgenic Cell Precursor Frequency Dictates Critical Aspects of the CD8+ T Cell Response to Infection

2007 • 415 citations

Memory and flexibility of cytokine gene expression as separable properties of human TH1 and TH2 lymphocytes

2002 • 353 citations

Naïve and Memory CD4 ⁺ T Cell Survival Controlled by Clonal Abundance

2006 • 348 citations

Arrested Differentiation, the Self-Renewing Memory Lymphocyte, and Vaccination

2001 • 264 citations

Emerging Challenges in Regulatory T Cell Function and Biology

2007 • 245 citations

A role for the immunological synapse in lineage commitment of CD4 lymphocytes

2004 • 180 citations

CD4 T cells integrate signals delivered during successive DC encounters in vivo

2005 • 158 citations

CD4+ T cells that enter the draining lymph nodes after antigen injection participate in the primary response and become central–memory cells

2006 • 151 citations

Visualization of IL-12/23p40 In Vivo Reveals Immunostimulatory Dendritic Cell Migrants that Promote Th1 Differentiation

2006 • 107 citations

CD8 single-cell gene coexpression reveals three different effector types present at distinct phases of the immune response

2007 • 91 citations

Competition for antigen determines the stability of T cell–dendritic cell interactions during clonal expansion

2007 • 87 citations

Single-cell dynamics of T-cell priming

2007 • 80 citations