Pip, a lymphoid-restricted IRF, contains a regulatory domain that is important for autoinhibition and ternary complex formation with the Ets factor PU.1.

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

1989 • 7,496 citations

Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins

1978 • 4,566 citations

TRANSCRIPTIONAL RESPONSES TO POLYPEPTIDE LIGANDS: The JAK-STAT Pathway

1995 • 1,826 citations

Regulation of Inducible and Tissue-Specific Gene Expression

1987 • 1,640 citations

Requirement of Transcription Factor PU.1 in the Development of Multiple Hematopoietic Lineages

1994 • 1,506 citations

The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene

1990 • 993 citations

Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method.

1988 • 983 citations

Structurally similar but functionally distinct factors, IRF-1 and IRF-2, bind to the same regulatory elements of IFN and IFN-inducible genes

1989 • 970 citations

I kappa B interacts with the nuclear localization sequences of the subunits of NF-kappa B: a mechanism for cytoplasmic retention.

1992 • 731 citations

Characterization of SAP-1, a protein recruited by serum response factor to the c-fos serum response element

1992 • 688 citations

Transcription activation by the adenovirus E1a protein

1989 • 667 citations

[72] Identification of regulatory elements of cloned genes with functional assays

1987 • 477 citations

Pip, a novel IRF family member, is a lymphoid-specific, PU.1-dependent transcriptional activator.

1995 • 451 citations

Phosphorylation of CREB at Ser-133 Induces Complex Formation with CREB-Binding Protein via a Direct Mechanism

1996 • 396 citations

Subunit of an alpha-interferon-responsive transcription factor is related to interferon regulatory factor and Myb families of DNA-binding proteins.

1992 • 387 citations

Absence of the type I IFN system in EC cells: Transcriptional activator (IRF-1) and repressor (IRF-2) genes are developmentally regulated

1990 • 377 citations

Induction of endogenous IFN-α and IFN-β genes by a regulatory transcription factor, IRF-1

1989 • 368 citations

An interferon gamma-regulated protein that binds the interferon-inducible enhancer element of major histocompatibility complex class I genes.

1990 • 368 citations

PU.1 recruits a second nuclear factor to a site important for immunoglobulin kappa 3' enhancer activity.

1992 • 362 citations

Immunoglobulin Gene Transcription

1991 • 294 citations

Effect of PU.1 phosphorylation on interaction with NF-EM5 and transcriptional activation

1993 • 278 citations

The octamer-binding proteins form multi-protein--DNA complexes with the HSV alpha TIF regulatory protein.

1989 • 245 citations

Molecular cloning ofLSIRF, a lymphoid-specific member of the interferon regulatory factor family that binds the interferon-stimulated response element (ISRE)

1995 • 237 citations

MATα1 protein, a yeast transcription activator, binds synergistically with a second protein to a set of cell-type-specific genes

1987 • 236 citations

A novel repression module, an extensive activation domain, and a bipartite nuclear localization signal defined in the immediate-early transcription factor Egr-1.

1993 • 223 citations

V(D)J recombination in B cells is impaired but not blocked by targeted deletion of the immunoglobulin heavy chain intron enhancer.

1993 • 219 citations

PU.1 is not essential for early myeloid gene expression but is required for terminal myeloid differentiation

1995 • 200 citations

A Novel Interferon Regulatory Factor Family Transcription Factor, ICSAT/Pip/LSIRF, That Negatively Regulates the Activity of Interferon-Regulated Genes

1996 • 197 citations

Interferon consensus sequence-binding protein, a member of the interferon regulatory factor family, suppresses interferon-induced gene transcription.

1993 • 189 citations

PU.1 is a component of a multiprotein complex which binds an essential site in the murine immunoglobulin lambda 2-4 enhancer.

1993 • 188 citations

Modulation of Transcription Factor Ets-1 DNA Binding: DNA-Induced Unfolding of an α Helix

1995 • 177 citations

Deletion of the Igκ Light Chain Intronic Enhancer/Matrix Attachment Region Impairs but Does Not Abolish VκJκ Rearrangement

1996 • 172 citations

Molecular interactions between interferon consensus sequence binding protein and members of the interferon regulatory factor family.

1994 • 167 citations

Mouse beta-globin DNA-binding protein B1 is identical to a proto-oncogene, the transcription factor Spi-1/PU.1, and is restricted in expression to hematopoietic cells and the testis.

1993 • 152 citations

Characterization of the Cooperative Function of Inhibitory Sequences in Ets-1

1996 • 145 citations

Ets-related protein PU.1 regulates expression of the immunoglobulin J-chain gene through a novel Ets-binding element.

1993 • 129 citations

Two Domains of ISGF3γ That Mediate Protein-DNA and Protein-Protein Interactions during Transcription Factor Assembly Contribute to DNA-Binding Specificity

1993 • 124 citations

Characterization of a cellular factor which interacts functionally with Oct-1 in the assembly of a multicomponent transcription complex

1990 • 116 citations

Regulation of the interferon system and cell growth by the IRF transcription factors

1995 • 115 citations

Functional Domain Analysis of Interferon Consensus Sequence Binding Protein (ICSBP) and Its Association with Interferon Regulatory Factors

1995 • 99 citations

B lymphocyte activation

1981 • 59 citations

The 3′ enhancer region determines the B/T specificity and pro-B/pre-B specificity of immunoglobulin Vκ-Jκ joining

1995 • 59 citations

Transcription revisited: a commentary on the 1995 Cold Spring Harbor Laboratory meeting, "Mechanisms of Eukaryotic Transcription".

1996 • 46 citations

Characterization of the Human Immunoglobulin Kappa Gene 3' Enhancer: Functional Importance of Three Motifs That Demonstrate B-Cell-Specific In Vivo Footprints

1992 • 41 citations

The interferon‐stimulated gene 54 K promoter contains two adjacent functional interferon‐stimulated response elements of different strength, which act synergistically for maximal interferon‐α inducibility

1994 • 39 citations

Inhibition of human immunodeficiency virus type 1 and vaccinia virus infection by a dominant negative factor of the interferon regulatory factor family expressed in monocytic cells.

1996 • 35 citations

Interferons as cell growth inhibitors and antitumor factors : proceedings of a UCLA Symposium held in Steamboat Springs, Colorado, April 6-12, 1986

1986 • 1 citations