Interleukin 1 and tumor necrosis factor enhance transcription from the SV40 early promoter in a T cell line

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Secretory products of macrophages.

1987 • 2,670 citations

Analysis of single- and double-stranded nucleic acids on polyacrylamide and agarose gels by using glyoxal and acridine orange.

1977 • 2,408 citations

Regulation of Inducible and Tissue-Specific Gene Expression

1987 • 1,640 citations

Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs

1985 • 1,594 citations

[68] Transcription maps of polyoma virus-specific RNA: Analysis by two-dimensional nuclease S1 gel mapping

1980 • 1,430 citations

Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose

1986 • 1,100 citations

Cloning and expression of murine interleukin-1 cDNA in Escherichia coli

1984 • 820 citations

Transcriptional regulation of hemoglobin switching in chicken embryos.

1981 • 800 citations

Trans-acting protein factors and the regulation of eukaryotic transcription: lessons from studies on DNA tumor viruses.

1988 • 736 citations

Molecular cloning of cDNA encoding human interleukin-2 receptor

1984 • 567 citations

Multiple actions of interleukin 6 within a cytokine network

1988 • 536 citations

Endotoxin and tumor necrosis factor induce interleukin-1 gene expression in adult human vascular endothelial cells.

1986 • 496 citations

GENERATION OF CYTOTOXIC T LYMPHOCYTES IN VITRO

1974 • 488 citations

Two promoters of different strengths control the transcription of the mouse alpha-amylase gene Amy-1a in the parotid gland and the liver

1983 • 469 citations

The cell surface receptors for interleukin-1α and interleukin-1β are identical

1986 • 422 citations

Interleukin-1 stimulates diacylglycerol production in T lymphocytes by a novel mechanism

1988 • 413 citations

Multiple biological activities of human recombinant interleukin 1.

1986 • 372 citations

A urine inhibitor of interleukin 1 activity that blocks ligand binding.

1987 • 351 citations

The human transferrin receptor gene: genomic organization, and the complete primary structure of the receptor deduced from a cDNA sequence

1984 • 337 citations

Molecular cloning of mouse tumour necrosis factor cDNA and its eukaryotic expression

1985 • 266 citations

Action of recombinant human interleukin 6, interleukin 1β and tumor necrosis factor α on the mRNA induction of acute‐phase proteins

1988 • 254 citations

Tumor necrosis factor enhances HLA-A,B,C and HLA-DR gene expression in human tumor cells.

1987 • 248 citations

Additive effects of interleukin 1 and tumour necrosis factor-alpha on the accumulation of the three granulocyte and macrophage colony-stimulating factor mRNAs in human endothelial cells.

1987 • 238 citations

Recombinant interleukin 1 suppresses lipoprotein lipase activity in 3T3-L1 cells.

1985 • 235 citations

Number and organization of actin-related sequences in the mouse genome

1983 • 232 citations

Characterization of a monoclonal antibody (5E9) that defines a human cell surface antigen of cell activation.

1981 • 232 citations

Transcription from the stromelysin promoter is induced by interleukin-1 and repressed by dexamethasone.

1987 • 217 citations

The inducible cytotoxic T-lymphocyte-associated gene transcript CTLA-1 sequence and gene localization to mouse chromosome 14

1986 • 197 citations

The interleukin 1 receptor. Dynamics of interleukin 1 binding and internalization in T cells and fibroblasts.

1987 • 190 citations

Binding of human tumor necrosis factor to high affinity receptors on HeLa and lymphoblastoid cells sensitive to growth inhibition.

1985 • 183 citations

Clustering of RNA polymerase B molecules in the 5′ moiety of the adult β-globin gene of hen erythrocytes

1981 • 168 citations

Tumor necrosis factor alpha/cachectin is a growth factor for thymocytes. Synergistic interactions with other cytokines.

1988 • 164 citations

Optimized Hybridization of DNA Blotted and Fixed to Nitrocellulose and Nylon Membranes

1987 • 159 citations

Tumor necrosis factor and interleukin-1 cause a rapid and transient stimulation of c-fos and c-myc mRNA levels in human fibroblasts.

1987 • 150 citations

Granules of cytolytic T-lymphocytes contain two serine esterases.

1986 • 148 citations

Murine cell surface transferrin receptor: Studies with an anti‐receptor monoclonal antibody

1982 • 131 citations

Hepatocyte-stimulating factor, beta 2 interferon, and interleukin-1 enhance expression of the rat alpha 1-acid glycoprotein gene via a distal upstream regulatory region.

1988 • 120 citations

Recombinant human cachectin/tumor necrosis factor but not interleukin-1 alpha downregulates lipoprotein lipase gene expression at the transcriptional level in mouse 3T3-L1 adipocytes.

1988 • 107 citations

Analysis of a bacterial hygromycin B resistance gene by transcriptional and translational fusions and by DNA sequencing

1983 • 105 citations

Nucleotide sequence of mouse IL-2 receptor cDNA and its comparison with the human IL-2 receptor sequence

1985 • 96 citations

DNA sequence comparison between two tissue-specific variants of the autonomous parvovirus, minute virus of mice

1985 • 87 citations

Construction of a fusion gene that confers resistance against hygromycin B to mammalian cells in culture

1985 • 86 citations

Structure and expression of the mouse beta 2-microglobulin gene isolated from somatic and non-expressing teratocarcinoma cells.

1983 • 82 citations

Hybrids between rat lymphoma and mouse T cells with inducible cytolytic activity

1982 • 81 citations

Tumor necrosis factor inhibits MYC expression in HL-60 cells at the level of mRNA transcription.

1987 • 77 citations

Appearance of cytolytic granules upon induction of cytolytic activity in CTL-hybrids.

1985 • 65 citations

cDNA cloning of granzyme C, a granule-associated serine protease of cytolytic T lymphocytes.

1988 • 57 citations

Characterization of soluble factors that induce the cytolytic activity and the expression of T cell growth factor receptors of a T cell hybrid.

1984 • 54 citations

Another chapter in the long history of endotoxin

1987 • 53 citations

Light scatter analysis and sorting of cells activated in mixed leukocyte culture

1982 • 41 citations

Recombinant tumor necrosis factor can induce interleukin 2 receptor expression and cytolytic activity in a rat × mouse T cell hybrid

1987 • 40 citations

trans-activation of the simian virus 40 enhancer by a pX product of human T-cell leukemia virus type I

1988 • 23 citations

Expression of the tumor necrosis factor locus is not necessary for the cytolytic activity of T lymphocytes.

1988 • 21 citations