Tumor necrosis factor inhibits MYC expression in HL-60 cells at the level of mRNA transcription.

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

An endotoxin-induced serum factor that causes necrosis of tumors.

1975 • 4,522 citations

Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor

1983 • 2,350 citations

Induction of differentiation of the human promyelocytic leukemia cell line (HL-60) by retinoic acid.

1980 • 1,997 citations

Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin

1984 • 1,738 citations

Terminal differentiation of human promyelocytic leukemia cells induced by dimethyl sulfoxide and other polar compounds.

1978 • 1,624 citations

Recombinant Human Tumor Necrosis Factor-α: Effects on Proliferation of Normal and Transformed Cells in Vitro

1985 • 1,596 citations

Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factors

1986 • 1,433 citations

Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts.

1985 • 1,240 citations

Stimulation of the adherence of neutrophils to umbilical vein endothelium by human recombinant tumor necrosis factor.

1985 • 1,056 citations

Human promyelocytic leukemia cells in culture differentiate into macrophage-like cells when treated with a phorbol diester.

1979 • 1,019 citations

Transcriptional regulation of the ovalbumin and conalbumin genes by steroid hormones in chick oviduct.

1979 • 975 citations

Activation of human polymorphonuclear neutrophil functions by interferon-gamma and tumor necrosis factors.

1985 • 922 citations

Human tumor necrosis factor. Production, purification, and characterization.

1985 • 922 citations

Fibroblast growth enhancing activity of tumor necrosis factor and its relationship to other polypeptide growth factors.

1986 • 674 citations

Molecular Cloning of the Complementary DNA for Human Tumor Necrosis Factor

1985 • 633 citations

Cyclosporin A inhibits T-cell growth factor gene expression at the level of mRNA transcription.

1984 • 623 citations

Antigens on human monocytes identified by monoclonal antibodies.

1981 • 583 citations

Induction of β2-interferon by tumor necrosis factor: A homeostatic mechanism in the control of cell proliferation

1986 • 577 citations

A Macrophage Factor Inhibits Adipocyte Gene Expression: An in Vitro Model of Cachexia

1985 • 525 citations

Regulation of myc gene expression in HL-60 leukaemia cells by a vitamin D metabolite

1983 • 500 citations

Recombinant human tumor necrosis factor increases mRNA levels and surface expression of HLA-A,B antigens in vascular endothelial cells and dermal fibroblasts in vitro.

1986 • 496 citations

Cloning and expression in Escherichia coli of the gene for human tumour necrosis factor

1985 • 464 citations

1α,25-Dihydroxyvitamin D3 induces differentiation of human myeloid leukemia cells

1981 • 460 citations

Human tumor necrosis factor produced by human B-cell lines: synergistic cytotoxic interaction with human interferon.

1983 • 458 citations

Tumor necrosis factor: specific binding and internalization in sensitive and resistant cells.

1985 • 430 citations

Macrophages as a source of tumoricidal activity (tumor-necrotizing factor)

1980 • 398 citations

Isolation and partial nucleotide sequence of a cDNA clone for human histocompatibility antigen HLA-B by use of an oligodeoxynucleotide primer.

1981 • 374 citations

Close link between reduction of c-myc expression by interferon and G0/G1 arrest

1985 • 358 citations

Deregulated expression of c-myc by murine erythroleukaemia cells prevents differentiation

1986 • 321 citations

Expression of a transfected human c-myconcogene inhibits differentiation of a mouse erythroleukaemia cell line

1986 • 309 citations

Sequential expression of genes involved in human T lymphocyte growth and differentiation.

1985 • 291 citations

Nuclear Localization and DNA Binding Properties of a Protein Expressed by Human c- myc Oncogene

1984 • 288 citations

Cellular receptor for 125I-labeled tumor necrosis factor: specific binding, affinity labeling, and relationship to sensitivity.

1985 • 287 citations

Initial characterization of monoclonal antibodies against human monocytes.

1980 • 276 citations

Tumor necrosis factor and lymphotoxin induce differentiation of human myeloid cell lines in synergy with immune interferon.

1986 • 261 citations

Regulation of cell proliferation and differentiation by interferons

1985 • 241 citations

Association of amplified oncogene c-myc with an abnormally banded chromosome 8 in a human leukaemia cell line

1983 • 152 citations

Interferon regulates c-myc gene expression in Daudi cells at the post-transcriptional level.

1985 • 149 citations

High affinity binding of 125I-labeled human tumor necrosis factor (LuKII) to specific cell surface receptors.

1985 • 118 citations

Quantification and characterization of high‐affinity membrane receptors for tumor necrosis factor on human leukemic cell lines

1986 • 110 citations

Initial Characterization of a Spontaneous Interferon Secreted During Growth and Differentiation of Friend Erythroleukemia Cells

1982 • 70 citations

Quantitation and characterization of gamma-interferon receptors on human tumor cells.

1986 • 52 citations

Initial Characterization of a Spontaneous Interferon Secreted During Growth and Differentiation of Friend Erythroleukemia Cells

1982 • 27 citations