Molecular cloning of a group of mouse pancreatic islet beta-cell-related genes by random cDNA sequencing

Improved tools for biological sequence comparison.

1988 • 11,455 citations

Differential Display of Eukaryotic Messenger RNA by Means of the Polymerase Chain Reaction

1992 • 5,105 citations

Rapid and Sensitive Protein Similarity Searches

1985 • 4,091 citations

Complementary DNA Sequencing: Expressed Sequence Tags and Human Genome Project

1991 • 2,286 citations

Sequence and gene organization of mouse mitochondrial DNA

1981 • 1,712 citations

Cloning the Differences Between Two Complex Genomes

1993 • 1,301 citations

Establishment of a Pancreatic β Cell Line That Retains Glucose-Inducible Insulin Secretion: Special Reference to Expression of Glucose Transporter Isoforms*

1990 • 1,212 citations

Mutation in mitochondrial tRNALeu(UUR) gene in a large pedigree with maternally transmitted type II diabetes mellitus and deafness

1992 • 1,103 citations

Close linkage of glucokinase locus on chromosome 7p to early-onset non-insulin-dependent diabetes mellitus

1992 • 620 citations

Maternally transmitted diabetes and deafness associated with a 10.4 kb mitochondrial DNA deletion

1992 • 612 citations

Nonsense mutation in the glucokinase gene causes early-onset non-insulin-dependent diabetes mellitus

1992 • 610 citations

Large scale cDNA sequencing for analysis of quantitative and qualitative aspects of gene expression

1992 • 528 citations

Linkage of type 2 diabetes to the glucokinase gene

1992 • 386 citations

3,400 new expressed sequence tags identify diversity of transcripts in human brain

1993 • 292 citations

Rapid, small-scale RNA isolation from tissue culture cells.

1991 • 216 citations

Characterization of the two nonallelic genes encoding mouse preproinsulin

1986 • 165 citations

Conservation of the sequence of islet amyloid polypeptide in five mammals is consistent with its putative role as an islet hormone.

1989 • 127 citations

Subtractive cDNA cloning using oligo(dt)₃₀-latex and PCR: isolation of cDNA clones specific to undifferentiated human embryonal carcinoma cells

1991 • 123 citations

A novel system for large-scale sequencing of cDNA by PCR amplification

1991 • 76 citations

A molecular inventory of human pancreatic islets: sequence analysis of 1000 cDNA clones

1993 • 74 citations