Gene regulation: translational initiation by internal ribosome binding

An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs

1987 • 5,139 citations

The scanning model for translation: an update.

1989 • 3,525 citations

Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA

1988 • 1,884 citations

An analysis of vertebrate mRNA sequences: intimations of translational control.

1991 • 1,655 citations

A segment of the 5' nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation

1988 • 1,325 citations

TRANSLATIONAL CONTROL IN MAMMALIAN CELLS

1991 • 1,041 citations

Internal ribosome entry site within hepatitis C virus RNA

1992 • 914 citations

Phosphorylation of initiation factor 2α by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast

1992 • 768 citations

Mechanism and regulation of eukaryotic protein synthesis

1992 • 591 citations

Inhibition of HeLa cell protein synthesis following poliovirus infection correlates with the proteolysis of a 220,000-dalton polypeptide associated with eucaryotic initiation factor 3 and a cap binding protein complex.

1982 • 580 citations

Internal initiation of translation mediated by the 5′ leader of a cellular mRNA

1991 • 554 citations

Site-specific modification of pre-mRNA: the 2'-hydroxyl groups at the splice sites

1992 • 466 citations

Cap-independent translation of encephalomyocarditis virus RNA: structural elements of the internal ribosomal entry site and involvement of a cellular 57-kD RNA-binding protein.

1990 • 428 citations

Complete nucleotide sequences of all three poliovirus serotype genomes

1984 • 421 citations

Prokaryotic-like cis elements in the cap-independent internal initiation of translation on picornavirus RNA

1992 • 275 citations

Cap-independent translation of poliovirus mRNA is conferred by sequence elements within the 5' noncoding region.

1988 • 273 citations

A cellular protein that binds to the 5'-noncoding region of poliovirus RNA: implications for internal translation initiation.

1989 • 271 citations

Homeotic gene Antennapedia mRNA contains 5'-noncoding sequences that confer translational initiation by internal ribosome binding.

1992 • 215 citations

Initiation of encephalomyocarditis virus RNA translation: the authentic initiation site is not selected by a scanning mechanism.

1990 • 205 citations

Cap-Independent Translation of Picornavirus RN As: Structure and Function of the Internal Ribosomal Entry Site

1990 • 205 citations

Functional analysis of the internal translation initiation site of foot-and-mouth disease virus

1990 • 202 citations

Mechanism and regulation of eukaryotic protein synthesis.

1992 • 199 citations

Structural and functional analysis of the ribosome landing pad of poliovirus type 2: in vivo translation studies

1991 • 185 citations

Translation of poliovirus RNA: role of an essential cis-acting oligopyrimidine element within the 5' nontranslated region and involvement of a cellular 57-kilodalton protein

1991 • 155 citations

A single base deletion in the Tfm androgen receptor gene creates a short-lived messenger RNA that directs internal translation initiation.

1991 • 151 citations

Inability of circular mRNA to attach to eukaryotic ribosomes

1979 • 143 citations

A Consideration of Alternative Models for the Initiation of Translation in Eukaryotes

1992 • 137 citations

Interaction of a cellular 57-kilodalton protein with the internal translation initiation site of foot-and-mouth disease virus

1991 • 135 citations

Translation of glucose-regulated protein 78/immunoglobulin heavy-chain binding protein mRNA is increased in poliovirus-infected cells at a time when cap-dependent translation of cellular mRNAs is inhibited.

1989 • 134 citations

Translational enhancement of the poliovirus 5' noncoding region mediated by virus-encoded polypeptide 2A.

1992 • 134 citations

Internal binding of eucaryotic ribosomes on poliovirus RNA: translation in HeLa cell extracts

1989 • 130 citations

Cardioviral internal ribosomal entry site is functional in a genetically engineered dicistronic poliovirus

1992 • 129 citations

Cell proteins bind to multiple sites within the 5' untranslated region of poliovirus RNA.

1989 • 116 citations

Dual initiation sites of protein synthesis on foot-and-mouth disease virus RNA are selected following internal entry and scanning of ribosomes in vivo.

1992 • 110 citations

Initiation of translation of human rhinovirus RNA: Mapping the internal ribosome entry site

1992 • 109 citations

Translation in Mammalian Cells of a Gene Linked to the Poliovirus 5′ Noncoding Region

1988 • 108 citations

Structure of transcripts from the homeotic Antennapedia gene of Drosophila melanogaster: two promoters control the major protein-coding region.

1986 • 107 citations

In vitro mutational analysis of cis-acting RNA translational elements within the poliovirus type 2 5' untranslated region

1991 • 103 citations

An RNA hairpin at the extreme 5' end of the poliovirus RNA genome modulates viral translation in human cells

1991 • 101 citations

Internal entry of ribosomes on a tricistronic mRNA encoded by infectious bronchitis virus

1992 • 100 citations

Linker scanning mutagenesis of the internal ribosome entry site of poliovirus RNA

1992 • 93 citations

Eukaryotic initiation factor (eIF)-4F. Implications for a role in internal initiation of translation

1991 • 91 citations

Multiple transcripts from the Antennapedia gene of Drosophila melanogaster.

1986 • 75 citations

Binding of Ribosomes to Linear and Circular Forms of the 5′‐Terminal Leader Fragment of Tobacco‐Mosaic‐Virus RNA

1981 • 75 citations

5′ end-dependent translation initiation of hepatitis C viral RNA and the presence of putative positive and negative translational control elements within the 5′ untranslated region

1992 • 73 citations

Translational attenuation of ermC: A deletion analysis

1982 • 67 citations

Eukaryotic initiation factors-4E and -4F stimulate 5' cap-dependent as well as internal initiation of protein synthesis.

1992 • 66 citations

Poliovirus Translation

1990 • 66 citations

The cap-binding protein complex in uninfected and poliovirus-infected HeLa cells.

1987 • 66 citations

Conservation of RNA-protein interactions among picornaviruses

1992 • 63 citations

Comparative studies of Drosophila Antennapedia genes.

1992 • 40 citations

Cap-independent translation by the 5' untranslated region of Theiler's murine encephalomyelitis virus

1992 • 35 citations

Translation of Poliovirus mRNA

1990 • 29 citations

Terminal 7-methyl-guanosine cap structure on the normally uncapped 5' noncoding region of poliovirus mRNA inhibits its translation in mammalian cells

1991 • 20 citations

Translation Start Sites and mRNA Leaders

1993 • 8 citations

Internal Entry of Ribosomes on a Tricistronic mRNA Encoded by Infectious Bronchitis Virus

1992 • 6 citations