Back to search

Vegfb gene knockout mice display reduced pathology and synovial angiogenesis in both antigen‐induced and collagen‐induced models of arthritis

Data up to Jan 2025

Published2003
Citations135
References40

Total Citations Per Year

Abstract

References (40)

Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

1995 • 3,977 citations

Vascular endothelial growth factor (VEGF) and its receptors

1999 • 3,498 citations

The fms -Like Tyrosine Kinase, a Receptor for Vascular Endothelial Growth Factor

1992 • 2,042 citations

Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions

2001 • 1,640 citations

Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor

1992 • 1,528 citations

Hyperplasia of Lymphatic Vessels in VEGF-C Transgenic Mice

1997 • 1,280 citations

VEGF-D promotes the metastatic spread of tumor cells via the lymphatics

2001 • 1,217 citations

Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR.

1994 • 1,104 citations

Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1

2002 • 1,066 citations

Isolation of a human placenta cDNA coding for a protein related to the vascular permeability factor.

1991 • 999 citations

Inhibition of Silencing and Accelerated Aging by Nicotinamide, a Putative Negative Regulator of Yeast Sir2 and Human SIRT1

2002 • 971 citations

A requirement for neuropilin-1 in embryonic vessel formation

1999 • 830 citations

Vascular endothelial growth factor B, a novel growth factor for endothelial cells.

1996 • 788 citations

Vascular endothelial growth factor B (VEGF-B) binds to VEGF receptor-1 and regulates plasminogen activator activity in endothelial cells

1998 • 551 citations

Angiogenesis: Implications for rheumatoid arthritis

1998 • 512 citations

Involvement of Flt-1 tyrosine kinase (vascular endothelial growth factor receptor-1) in pathological angiogenesis.

2001 • 345 citations

Neuropilin-1 Is a Placenta Growth Factor-2 Receptor

1998 • 344 citations

Mice Lacking the Vascular Endothelial Growth Factor-B Gene ( Vegfb ) Have Smaller Hearts, Dysfunctional Coronary Vasculature, and Impaired Recovery From Cardiac Ischemia

2000 • 323 citations

Homologs of vascular endothelial growth factor are encoded by the poxvirus orf virus

1994 • 310 citations

Selective inhibition of vascular endothelial growth factor (VEGF) receptor 2 (KDR/Flk-1) activity by a monoclonal anti-VEGF antibody blocks tumor growth in mice.

2000 • 309 citations

Differential Binding of Vascular Endothelial Growth Factor B Splice and Proteolytic Isoforms to Neuropilin-1

1999 • 304 citations

Heterodimers of Placenta Growth Factor/Vascular Endothelial Growth Factor

1996 • 295 citations

Signaling via Vascular Endothelial Growth Factor Receptors

1999 • 281 citations

Vascular endothelial growth factor (VEGF)-like protein from orf virus NZ2 binds to VEGFR2 and neuropilin-1

1999 • 276 citations

Protection from Collagen-Induced Arthritis in Granulocyte-Macrophage Colony-Stimulating Factor-Deficient Mice

1998 • 233 citations

Genomic Organization of the Mouse and Human Genes for Vascular Endothelial Growth Factor B (VEGF-B) and Characterization of a Second Splice Isoform

1996 • 217 citations

Collagen-induced arthritis in C57BL/6 (H-2b) mice: new insights into an important disease model of rheumatoid arthritis

2000 • 214 citations

Vascular Endothelial Growth Factor-B–Deficient Mice Display an Atrial Conduction Defect

2001 • 190 citations

Angiogenesis inhibition suppresses collagen arthritis.

1992 • 188 citations

Structure, Expression and Receptor-Binding Properties of Novel Vascular Endothelial Growth Factors

1999 • 170 citations

Treatment with Soluble VEGF Receptor Reduces Disease Severity in Murine Collagen-Induced Arthritis

2000 • 160 citations

Efficacy of sustained blood levels of interleukin-1 receptor antagonist in animal models of arthritis: Comparison of efficacy in animal models with human clinical data

1999 • 155 citations

Vascular Endothelial Growth Factor Expression and Regulation of Murine Collagen-Induced Arthritis

2000 • 135 citations

Expression of vascular endothelial growth factor isoforms and their receptors Flt-1, KDR, and neuropilin-1 in synovial tissues of rheumatoid arthritis

2000 • 120 citations

Placenta growth factor (PlGF) induces vascular endothelial growth factor (VEGF) secretion from mononuclear cells and is co-expressed with VEGF in synovial fluid

2000 • 116 citations

Neutralization of Vascular Endothelial Growth Factor Prevents Collagen-Induced Arthritis and Ameliorates Established Disease in Mice

2001 • 106 citations

A Mutant Form of Vascular Endothelial Growth Factor (VEGF) That Lacks VEGF Receptor-2 Activation Retains the Ability to Induce Vascular Permeability

1999 • 105 citations

Isoform-specific Expression of VEGF-B in Normal Tissues and Tumors

2001 • 79 citations

Extracellular matrix tenascin‐X in combination with vascular endothelial growth factor B enhances endothelial cell proliferation

2000 • 74 citations

Age‐ and sex‐related differences in antigen‐induced arthritis in c57bl/10 mice

1989 • 19 citations

Cited By (0)

Loading...
Vegfb gene knockout mice display reduced pathology and synovial angiogenesis in both… (2003) – Arthritis & Rheumatism | Metascience Observatory Explorer