Phosphorylation-dependent Block of Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel by Exogenous R Domain Protein

Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA

1989 • 7,327 citations

ABC Transporters: From Microorganisms to Man

1992 • 3,956 citations

Purification and functional reconstitution of the cystic fibrosis transmembrane conductance regulator (CFTR)

1992 • 937 citations

Restoration of Inactivation in Mutants of Shaker Potassium Channels by a Peptide Derived from ShB

1990 • 752 citations

Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel

1991 • 658 citations

Correction of the cystic fibrosis defect in vitro by retrovirus-mediated gene transfer

1990 • 576 citations

Phosphorylation-regulated CI− channel in CHO cells stably expressing the cystic fibrosis gene

1991 • 564 citations

Destruction of Sodium Conductance Inactivation in Squid Axons Perfused with Pronase

1973 • 540 citations

Nucleoside triphosphates are required to open the CFTR chloride channel

1991 • 520 citations

Phosphorylation of the cystic fibrosis transmembrane conductance regulator.

1992 • 324 citations

Protein kinase A (PKA) still activates CFTR chloride channel after mutagenesis of all 10 PKA consensus phosphorylation sites

1993 • 296 citations

Effect of Deleting the R Domain on CFTR-Generated Chloride Channels

1991 • 271 citations

Control of CFTR chloride conductance by ATP levels through non-hydrolytic binding

1992 • 167 citations

Regulation of the cystic fibrosis transmembrane conductance regulator Cl- channel by negative charge in the R domain.

1993 • 148 citations

Phosphorylation by cAMP-Dependent Protein Kinase Causes a Conformational Change in the R Domain of the Cystic Fibrosis Transmembrane Conductance Regulator

1994 • 114 citations

Regulation of CFTR channel gating

1994 • 95 citations

Small linear chloride channels are endogenous to nonepithelial cells

1992 • 87 citations

Intracellular Loop between Transmembrane Segments IV and V of Cystic Fibrosis Transmembrane Conductance Regulator Is Involved in Regulation of Chloride Channel Conductance State

1995 • 71 citations

Cyclic AMP-dependent protein kinase activation of cystic fibrosis transmembrane conductance regulator chloride channels in planar lipid bilayers.

1992 • 61 citations

Slow conversions among subconductance states of cystic fibrosis transmembrane conductance regulator chloride channel

1996 • 39 citations