Long‐term survival in breast cancer related to overexpression of the c‐erbB‐2 oncoprotein: An immunohistochemical study using monoclonal antibody NCL‐CB11

Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/ neu Oncogene

1987 • 11,429 citations

Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. Analysis and examples

1977 • 8,468 citations

Studies of the HER-2/ neu Proto-Oncogene in Human Breast and Ovarian Cancer

1989 • 6,734 citations

Tyrosine Kinase Receptor with Extensive Homology to EGF Receptor Shares Chromosomal Location with neu Oncogene

1985 • 1,804 citations

The neu oncogene: an erb-B-related gene encoding a 185,000-Mr tumour antigen

1984 • 1,153 citations

Neu-Protein Overexpression in Breast Cancer

1988 • 860 citations

Overexpression of the EGF receptor-related proto-oncogene erbB-2 in human mammary tumor cell lines by different molecular mechanisms.

1987 • 619 citations

Expression of c-erbB-2 oncoprotein: a prognostic indicator in human breast cancer.

1989 • 592 citations

Correlation of c-erbB-2 gene amplification and protein expression in human breast carcinoma with nodal status and nuclear grading.

1988 • 570 citations

OVEREXPRESSION OF THE c-erbB-2 ONCOPROTEIN IN HUMAN BREAST CARCINOMAS: IMMUNOHISTOLOGICAL ASSESSMENT CORRELATES WITH GENE AMPLIFICATION

1987 • 409 citations

p185, a product of the neu proto-oncogene, is a receptorlike protein associated with tyrosine kinase activity.

1986 • 341 citations

Increased tyrosine kinase activity associated with the protein encoded by the activated neu oncogene.

1988 • 227 citations

Association of multiple copies of the c-erbB-2 oncogene with spread of breast cancer.

1987 • 214 citations

An immunohistochemical evaluation of c-erbB-2 expression in human breast carcinoma

1988 • 206 citations

Expression of the c‐erbB‐2 protein in normal and transformed cells

1987 • 197 citations

The cancer research campaign (King's/Cambridge trial for early breast cancer: Clinico-pathological aspects

1982 • 174 citations

Screening for breast cancer: the Swedish trial.

1981 • 149 citations

Absence of activating transmembrane mutations in the c-erbB-2 proto-oncogene in human breast cancer.

1990 • 143 citations

Immunohistochemical distribution of c‐erbB‐2 in infiltrating and in situ breast cancer

1988 • 130 citations

NCL‐CB11, a new monoclonal antibody recognizing the internal domain of the c‐erbB‐2 oncogene protein effective for use on formalin‐fixed, paraffin‐embedded tissue

1990 • 108 citations

Amplification of the c-erb B-2 oncogene and prognosis of breast adenocarcinoma.

1990 • 95 citations

COMPARATIVE PATHOLOGY OF PREVALENT AND INCIDENT CANCERS DETECTED BY BREAST SCREENING

1986 • 83 citations

c‐erbB‐2 oncoprotein expression in mammary and extramammary Paget's disease: an immunohistochemical study

1990 • 75 citations

Pattern of expression of c-erbB-2 oncoprotein in human fetuses

1989 • 70 citations

Relationships between oestrogen receptor, epidermal growth factor receptor, ER‐D5, and P24 oestrogen regulated protein in human breast cancer

1988 • 36 citations

Breast cancer and a proto-oncogene.

1989 • 33 citations