Reappraisal of Aids — Is the oxidation induced by the risk factors the primary cause?

The Pharmacological Basis of Therapeutics

1976 • 8,675 citations

Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS)

1983 • 6,811 citations

Detection, Isolation, and Continuous Production of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and Pre-AIDS

1984 • 3,566 citations

Dietary Carcinogens and Anticarcinogens

1983 • 3,028 citations

The Pharmacological Basis of Therapeutics

1986 • 1,413 citations

Isolation of Human T-Cell Leukemia Virus in Acquired Immune Deficiency Syndrome (AIDS)

1983 • 1,222 citations

Amino Acid Homology Between the Encephalitogenic Site of Myelin Basic Protein and Virus: Mechanism for Autoimmunity

1985 • 941 citations

Acquired Immunodeficiency Syndrome: Epidemiologic, Clinical, Immunologic, and Therapeutic Considerations

1984 • 871 citations

Exchange of actin subunits at the leading edge of living fibroblasts: possible role of treadmilling.

1985 • 637 citations

Human T-lymphotropic retroviruses

1985 • 623 citations

Acquired Immunodeficiency Syndrome (AIDS) Associated with Transfusions

1984 • 591 citations

Murine Leukemia Virus: High-Frequency Activation in vitro by 5-Iododeoxyuridine and 5-Bromodeoxyuridine

1971 • 588 citations

Long-Term Cultures of HTLV-III—Infected T Cells: a Model of Cytopathology of T-Cell Depletion in AIDS

1986 • 537 citations

Ascorbate-Nitrite Reaction: Possible Means of Blocking the Formation of Carcinogenic N -Nitroso Compounds

1972 • 506 citations

Intrinsic and Extrinsic Factors in Protein Antigenic Structure

1985 • 481 citations

Characterization of gp41 as the Transmembrane Protein Coded by the HTLV-III/LAV Envelope Gene

1985 • 442 citations

Induction of Murine C-Type Viruses from Clonal Lines of Virus-Free BALB/3T3 Cells

1971 • 422 citations

ACQUIRED IMMUNODEFICIENCY IN AN INFANT: POSSIBLE TRANSMISSION BY MEANS OF BLOOD PRODUCTS

1983 • 382 citations

INTRAMEMBRANE PARTICLE AGGREGATION IN ERYTHROCYTE GHOSTS

1974 • 348 citations

Immunodeficiency in Female Sexual Partners of Men with the Acquired Immunodeficiency Syndrome

1983 • 313 citations

Epidemiologic Aspects of the Current Outbreak of Kaposi's Sarcoma and Opportunistic Infections

1982 • 309 citations

Intramembrane particle aggregation in erythrocyte ghosts. II. The influence of spectrin aggregation

1976 • 305 citations

The occurrence and possible functional significance of ‐S‐S‐ crosslinks in sperm heads, with particular reference to eutherian mammals

1974 • 302 citations

Immunologic Dysfunction in Heroin Addicts

1974 • 301 citations

DETERMINANTS OF RETROVIRUS (HTLV-III) ANTIBODY AND IMMUNODEFICIENCY CONDITIONS IN HOMOSEXUAL MEN

1984 • 299 citations

FOLLICULAR DENDRITIC CELLS AND VIRUS-LIKE PARTICLES IN AIDS-RELATED LYMPHADENOPATHY

1984 • 283 citations

Mechanisms of Immunosuppression in Cytomegaloviral Mononucleosis

1980 • 276 citations

Induction of HTLV-III/LAV from a Nonvirus-Producing T-Cell Line: Implications for Latency

1986 • 264 citations

ISOLATION OF NEW LYMPHOTROPIC RETROVIRUS FROM TWO SIBLINGS WITH HAEMOPHILIA B, ONE WITH AIDS

1984 • 251 citations

Epinephrine-induced changes in the distribution of lymphocyte subsets in peripheral blood of humans.

1983 • 249 citations

Induction of avian tumor viruses in normal cells by physical and chemical carcinogens

1971 • 247 citations

Treatment of fractures.

1947 • 235 citations

Alteration of T and null lymphocyte frequencies in the peripheral blood of human opiate addicts: in vivo evidence for opiate receptor sites on T lymphocytes.

1980 • 234 citations

Hormone-induced cell death. 2. Surface changes in thymocytes undergoing apoptosis.

1984 • 207 citations

Isolation of T-Lymphotropic Retrovirus Related to HTLV-III/LAV from Wild-Caught African Green Monkeys

1985 • 196 citations

Immunosuppression by seminal plasma and its possible clinical significance

1984 • 174 citations

AMYL NITRITE MAY ALTER T LYMPHOCYTES IN HOMOSEXUAL MEN

1982 • 169 citations

Nomenclature of Eukaryotic DNA Polymerases

1975 • 168 citations

ELISA HTLV RETROVIRUS ANTIBODY REACTIVITY ASSOCIATED WITH MALARIA AND IMMUNE COMPLEXES IN HEALTHY AFRICANS

1985 • 164 citations

Slow Persistent Infection Caused by Visna Virus: Role of Host Restriction

1977 • 163 citations

The mechanism of cell-mediated cytotoxicity. I. Killing by murine cytotoxic T lymphocytes requires cell surface thiols and activated proteases.

1980 • 155 citations

Identification and characterization of some bacterial membrane sulfhydryl groups which are targets of bacteriostatic and antibiotic action.

1984 • 154 citations

Acquired immune deficiency syndrome (AIDS) trends in the United States, 1978–1982

1984 • 144 citations

Effect of dietary 2-mercaptoethanol on the life span, immune system, tumor incidence and lipid peroxidation damage in spleen lymphocytes of aging BC3F1 mice

1984 • 101 citations

The formation of disulfide bonds in human protamines during sperm maturation

1979 • 97 citations

Germ cell-induced immune suppression in mice. Effect of inoculation of syngeneic spermatozoa on cell-mediated immune responses.

1982 • 95 citations

T4 lymphopenia in patients with active pulmonary tuberculosis.

1985 • 91 citations

Chronic immune stimulation by sperm alloantigens. Support for the hypothesis that spermatozoa induce immune dysregulation in homosexual males

1984 • 87 citations

SEPTAL LINES

1976 • 86 citations

Disproportionate lymphoid cell subsets in thalassaemia major: the relative contributions of transfusion and splenectomy

1985 • 77 citations

Regulation of the immune response in Plasmodium falciparum malaria. III. Proliferative response to antigen in vitro and subset composition of T cells from patients with acute infection or from immune donors.

1984 • 77 citations

Restoration of impaired immune functions in aging animals

1976 • 75 citations

Specificity of human antibodies to oncovirus glycoproteins: recognition of antigen by natural antibodies directed against carbohydrate structures.

1980 • 74 citations

Humans have antibodies capable of recognizing oncoviral glycoproteins: demonstration that these antibodies are formed in response to cellular modification of glycoproteins rather than as consequence of exposure to virus.

1980 • 74 citations

Opiate Receptor Function May Be Modulated Through an Oxidation-Reduction Mechanism

1980 • 73 citations

Energy coupling to nitrite respiration in the sulfate-reducing bacterium Desulfovibrio gigas

1983 • 69 citations

Contrasting effects of cyclophosphamide and prednisolone on the phenotype of human peripheral blood leukocytes

1983 • 68 citations

Molybdate reduction by Escherichia coli K-12 and its chl mutants.

1985 • 68 citations

Immunomodulating effects of antimicrobial agents

1980 • 67 citations

Immunology: Approaches to AIDS therapy

1986 • 66 citations

Nucleation of polar actin filament assembly by a positively charged surface.

1979 • 66 citations

Chronic Immune Stimulation by Sperm Alloantigens

1984 • 63 citations

A Genetic Switch in a Bacterial Virus

1982 • 62 citations

Pharmacological modification of immunoregulatory T lymphocytes . II. Modulation of T lymphocyte cell surface characteristics.

1982 • 58 citations

Expression of MuLV GP71-like antigen in normal mouse spleen cells induced by antigenic stimulation

1977 • 57 citations

Localization of Thiol and Disulfide Groups in Guinea Pig Spermatozoa During Maturation and Capacitation Using Bimane Fluorescent Labels

1984 • 56 citations

Pharmacological modification of immunoregulatory T lymphocytes. I. Effect of adenosine, H1 and H2 histamine agonists upon T lymphocyte regulation of B lymphocyte differentiation in vitro.

1982 • 52 citations

Analysis of lymphocyte subsets in patients with aplastic anaemia

1984 • 49 citations

Presence of natural autoantibodies in hyperimmunized mice.

1985 • 48 citations

Analysis of T cell subsets by monoclonal antibodies in patients with tuberculosis after in vitro stimulation with purified protein derivative of tuberculin.

1984 • 48 citations

Effects of Chemotherapeutic Agents on the Immune Response. II

1985 • 46 citations

DNA polymerase γ of human lymphoblasts

1977 • 46 citations

IMMUNE RECOVERY FOLLOWING ALLOGENEIC BONE MARROW TRANSPLANTATION

1985 • 45 citations

Cell Electrophoresis in Cancer and Other Clinical Research

1982 • 43 citations

Cytofluorometric study of nuclear sulphydryl and disulphide groups during sperm maturation in the mouse

1983 • 42 citations

Restoration of impaired immune functions in aging animals. II. Effect of mercaptoethanol in enhancing the reduced primary antibody responsiveness in vitro

1979 • 42 citations

Actin filaments in paramyxovirus-infected human fibroblasts studied by indirect immunofluorescence

1978 • 39 citations

The Epidemic of Acquired Immune Dysfunction in Homosexual Men and Its Sequelae—Opportunistic Infections, Kaposi’s Sarcoma and Other Malignancies: An Update and Interpretation

1982 • 36 citations

Changes in T-lymphocyte subsets during childhood Epstein-Barr virus infectious mononucleosis

1983 • 33 citations

Human T-Cell Leukemia Virus Linked to AIDS

1983 • 33 citations

Detection of reverse transcriptase in human breast tumours with poly(Cm)·oligo(dG)

1975 • 33 citations

Hormone-induced actin polymerization in rat hepatoma cells and human leucocytes

1985 • 33 citations

Evaluation of T cell subsets in Behçet's syndrome using anti-T cell monoclonal antibodies.

1985 • 33 citations

T‐Lymphocytes and the Subpopulations of T‐Helper and T‐Suppressor Cells Measured by Monoclonal Antibodies (T11, T4, and Ts) in Relation to Surgery Under Epidural and General Anaesthesia

1984 • 30 citations

Risk Factors Associated with AIDS in Haiti

1986 • 30 citations

Restoration of impaired immune functions in aging animals, IV. Action of 2-mercaptoethanol in enhancing age-reduced immune responsiveness

1980 • 29 citations

Delineation and Quantitation of Human Peripheral Blood Lymphocyte Subpopulations by Electrophoretic Mobility and Role of Surface Charge in Cell to Cell Interaction

1977 • 28 citations

Chemosterilant Action of Anthramycin: A Proposed Mechanism

1971 • 28 citations

The effect of reducing agents on factor VIII and other coagulation factors

1978 • 26 citations

Peripheral blood T-cell subsets studied by monoclonal antibodies in Type 1 (insulin-dependent) diabetes: effect of blood glucose control

1984 • 26 citations

Erythrocyte membrane alterations as the basis of chlorate toxicity

1984 • 25 citations

T-Subset Abnormalities in Thalassaemia intermedia: Possible Evidence for a Thymus Functional Deficiency

1984 • 25 citations

Reproduction of RNA Tumor Viruses

1975 • 24 citations

Deficient immune function of peripheral blood mononuclear cells from patients with Gardner syndrome.

1985 • 23 citations

Diagnostic Confusion from Lymphatic Lesions in Heroin Addicts

1973 • 23 citations

Production of nitrous oxide from nitrite in Klebsiella pneumoniae: mutants altered in nitrogen metabolism

1983 • 22 citations

The role of disulfide bonds in the acquisition of immunologic specificity

1962 • 22 citations

A Group Approach for Working with Families of the Elderly

1983 • 22 citations

A mitotic theory

1982 • 21 citations

The effect of uncoupler on the distribution of the electron flow between the terminal acceptors oxygen and nitrite in the cells of Paracoccus denitrificans

1983 • 16 citations

Modification of cellular protein sulfhydryl groups by activated soluble immune response suppressor.

1984 • 16 citations

Atopic Asthma: T-Cell Response to Corticosteroids

1985 • 13 citations

The influence of 2-mercaptoethanol on von willebrand factor and bovine platelet aggregating factor

1980 • 13 citations

Structure of the lymphocyte membrane. 3. Chemical nature of the guinea-pig lymphocyte membrane macromolecules reacting with heterologous ALS.

1972 • 13 citations

AIDS Trends: Projections from Limited Data

1985 • 13 citations

A study of the mechanism of Con A-induced immunosuppression in vivo

1984 • 10 citations

Lymphocyte subset ratios and factor VIII usage in haemophilia.

1985 • 8 citations

Consultation on "Star Wars"

1986 • 7 citations

Evidence that the redox state has a role in muscular contraction and relaxation.

1985 • 6 citations

An in vitro effect of ascorbate on the spontaneous reduction of sodium nitrite concentration in a reaction mixture.

1984 • 6 citations

Africa and the Origin of AIDS

1985 • 6 citations

Effect of chemotherapy on T-lymphocyte subsets in B-cell proliferative disorders

1985 • 3 citations

Lymphocyte differentiation: Control of antibody production

1983 • 2 citations

Electrophoretic characterization of specific antibody effects on lymphocytes.

1984 • 2 citations

AIDS: US blood-bank tests established

1985 • 2 citations

Spermatozoa and Immune Dysregulation in Homosexual Men-Reply

1984 • 1 citations

AIDS: Japan screens donated blood

1986 • 1 citations