Activation of the innate immune receptor Dectin-1 upon formation of a ‘phagocytic synapse’

Collaborative Induction of Inflammatory Responses by Dectin-1 and Toll-like Receptor 2

2003 • 1,593 citations

Dectin-1 Mediates the Biological Effects of β-Glucans

2003 • 1,167 citations

Dectin-1 is required for β-glucan recognition and control of fungal infection

2006 • 1,105 citations

Dectin-1 Is A Major β-Glucan Receptor On Macrophages

2002 • 964 citations

Human Dectin-1 Deficiency and Mucocutaneous Fungal Infections

2009 • 719 citations

Dectin-1 is required for host defense against Pneumocystis carinii but not against Candida albicans

2006 • 600 citations

β‐glucan recognition by the innate immune system

2009 • 587 citations

Myeloid C-type lectins in innate immunity

2006 • 505 citations

Dectin-1 activates Syk tyrosine kinase in a dynamic subset of macrophages for reactive oxygen production

2005 • 501 citations

Functional Anatomy of T Cell Activation and Synapse Formation

2009 • 437 citations

Syk kinase is required for collaborative cytokine production induced through Dectin‐1 and Toll‐like receptors

2008 • 360 citations

Dectin-1 Stimulation by Candida albicans Yeast or Zymosan Triggers NFAT Activation in Macrophages and Dendritic Cells

2007 • 352 citations

Differential High-Affinity Interaction of Dectin-1 with Natural or Synthetic Glucans Is Dependent upon Primary Structure and Is Influenced by Polymer Chain Length and Side-Chain Branching

2008 • 268 citations

Early Stop Polymorphism in Human DECTIN‐1 Is Associated with IncreasedCandidaColonization in Hematopoietic Stem Cell Transplant Recipients

2009 • 242 citations

A beta-glucan inhibitable receptor on human monocytes: its identity with the phagocytic receptor for particulate activators of the alternative complement pathway.

1985 • 216 citations

The C-type Lectin Receptors CLEC-2 and Dectin-1, but Not DC-SIGN, Signal via a Novel YXXL-dependent Signaling Cascade

2007 • 215 citations

Differential Use of CARD9 by Dectin-1 in Macrophages and Dendritic Cells

2009 • 193 citations

CD45, CD148, and Lyp/Pep: critical phosphatases regulating Src family kinase signaling networks in immune cells

2009 • 161 citations

Structurally Distinct Phosphatases CD45 and CD148 Both Regulate B Cell and Macrophage Immunoreceptor Signaling

2008 • 156 citations

Syk‐coupled C‐type lectin receptors that mediate cellular activation via single tyrosine based activation motifs

2010 • 155 citations

CLEC-2 Is a Phagocytic Activation Receptor Expressed on Murine Peripheral Blood Neutrophils

2009 • 124 citations

The tyrosine phosphatase CD148 is excluded from the immunologic synapse and down-regulates prolonged T cell signaling

2003 • 90 citations

β-Glucan Is a Fungal Determinant for Adhesion-Dependent Human Neutrophil Functions

2006 • 73 citations

Stepping into the Third Dimension

2007 • 40 citations