CpG islands in mammalian gene promoters are inherently resistant to de novo methylation

CpG-rich islands and the function of DNA methylation

1986 • 3,760 citations

CpG Islands in vertebrate genomes

1987 • 3,315 citations

Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells

1988 • 891 citations

High levels of De Novo methylation and altered chromatin structure at CpG islands in cell lines

1990 • 709 citations

Substrate and sequence specificity of a eukaryotic DNA methylase

1982 • 441 citations

Methylation of CpG sequences in eukaryotic DNA

1981 • 289 citations

Direct identification of the active-site nucleophile in a DNA (cytosine-5)-methyltransferase

1991 • 246 citations

SPKK, a new nucleic acid-binding unit of protein found in histone.

1989 • 237 citations

‘SPKK’ motifs prefer to bind to DNA at A/T-rich sites.

1989 • 184 citations

Unmethlated domains in vertebrate DNA

1983 • 173 citations

Cloning of a mammalian DNA methyltransferase

1988 • 126 citations

Retrovirus genomes methylated by mammalian but not bacterial methylase are non-infectious

1983 • 98 citations

The maintenance of methylation-free islands in transgenic mice.

1986 • 70 citations

Supercoiling-dependent sequence specificity of mammalian DNA methyitransferase

1987 • 50 citations

In vitromethylation of CpG-rich islands

1989 • 26 citations

Identification of the functional profilin gene, its localization to chromosome subband 17p13.3, and demonstration of its deletion in some patients with Miller-Dieker syndrome.

1990 • 20 citations

Non-C-G recognition sequences of DNA cytosin-5-methyltransferase from rat liver

1989 • 19 citations

In vitroDNA cytosine roethytation of cis-regulatory elements modulates c-Ha-ras promoter activity in vivo

1989 • 19 citations