uPAR and HER-2 gene status in individual breast cancer cells from blood and tissues

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Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/ neu Oncogene

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Use of Chemotherapy plus a Monoclonal Antibody against HER2 for Metastatic Breast Cancer That Overexpresses HER2

2001 • 11,070 citations

Trastuzumab plus Adjuvant Chemotherapy for Operable HER2-Positive Breast Cancer

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Trastuzumab after Adjuvant Chemotherapy in HER2-Positive Breast Cancer

2005 • 4,901 citations

Trastuzumab-Induced Hepatotoxicity: A Case Report

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Epidermal growth factor receptor (EGFR) signaling in cancer

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Circulating Tumor Cells in Patients with Breast Cancer Dormancy

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HER2 Amplification Ratios by Fluorescence In Situ Hybridization and Correlation with Immunohistochemistry in a Cohort of 6556 Breast Cancer Tissues

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Pooled Analysis of Prognostic Impact of Urokinase-Type Plasminogen Activator and Its Inhibitor PAI-1 in 8377 Breast Cancer Patients

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HER-2 gene amplification can be acquired as breast cancer progresses

2004 • 504 citations

The urokinase plasminogen activator system in cancer: recent advances and implication for prognosis and therapy.

2003 • 361 citations

EGFR gene amplification in breast cancer: correlation with epidermal growth factor receptor mRNA and protein expression and HER-2 status and absence of EGFR-activating mutations

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Targeted Therapy in Breast Cancer

2004 • 306 citations

Urokinase Plasminogen Activator and Its Inhibitor, PAI-1, as Prognostic Markers in Breast Cancer: From Pilot to Level 1 Evidence Studies

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Prognostic significance of the receptor for urokinase plasminogen activator in breast cancer.

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Urokinase plasminogen activator and urokinase plasminogen activator receptor in breast cancer

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The Influence of Polysomy 17 on HER2 Gene and Protein Expression in Adenocarcinoma of the Breast

2005 • 121 citations

Prognostic significance of soluble urokinase plasminogen activator receptor in serum and cytosol of tumor tissue from patients with primary breast cancer.

2002 • 115 citations

Urokinase-type plasminogen activator system and breast cancer (Review).

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The Urokinase Receptor as a Potential Target in Cancer Therapy

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Polysomy 17 in HER-2/neu Status Elaboration in Breast Cancer: Effect on Daily Practice

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Prognostic and predictive factors revisited

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Anti-erbB-2 antibody trastuzumab in the treatment of HER2-amplified breast cancer

2005 • 102 citations

Upregulation and activation of PKCα by ErbB2 through Src promotes breast cancer cell invasion that can be blocked by combined treatment with PKCα and Src inhibitors

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Polysomy of chromosome 17 in breast cancer tumors showing an overexpression of ERBB2: a study of 175 cases using fluorescence in situhybridization and immunohistochemistry

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Increased Expression of Urokinase-Type Plasminogen Activator mRNA Determines Adverse Prognosis in ErbB2-Positive Primary Breast Cancer

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Å6, a urokinase plasminogen activator (uPA)-derived peptide in patients with advanced gynecologic cancer: A phase I trial

2005 • 64 citations

HER-2/neu Testing in Breast Cancer

2003 • 59 citations

Cathepsin B, plasminogenactivator-inhibitor (PAI-1) and plasminogenactivator-receptor (uPAR) are prognostic factors for patients with non-small cell lung cancer.

2005 • 58 citations

Prognostic relevance of uPAR-del4/5 and TIMP-3 mRNA expression levels in breast cancer

2005 • 49 citations

Comparative evaluation of urokinase‐type plasminogen activator receptor expression in primary breast carcinomas and on metastatic tumor cells

2003 • 48 citations

Patterns of Aneusomy for Three Chromosomes in Individual Cells from Breast Cancer Tumors

2002 • 45 citations

Prognostic impact of urokinase-type plasminogen activator receptor (uPAR) in cytosols and pellet extracts derived from primary breast tumours

2001 • 43 citations

HER-2/neu Evaluation in Breast Cancer

2004 • 40 citations

Amplification of the urokinase gene and the sensitivity of prostate cancer cells to urokinase inhibitors

2005 • 16 citations