Granulocyte‐Macrophage Colony‐Stimulating Factor Induces Activation and Restores Respiratory Burst Activity in Monocytes from Septic Patients

Human mononuclear phagocyte inducible nitric oxide synthase (iNOS): analysis of iNOS mRNA, iNOS protein, biopterin, and nitric oxide production by blood monocytes and peritoneal macrophages

1995 • 420 citations

Gram-positive cell walls stimulate synthesis of tumor necrosis factor alpha and interleukin-6 by human monocytes

1994 • 347 citations

Regulation of the tissue factor gene

1995 • 275 citations

Role of Nitric Oxide

1998 • 269 citations

Human granulocyte-monocyte colony-stimulating factor and interleukin 3 stimulate monocyte cytotoxicity through a tumor necrosis factor- dependent mechanism

1988 • 221 citations

Recombinant human granulocyte/macrophage colony-stimulating factor enhances monocyte cytotoxicity and secretion of tumor necrosis factor alpha and interferon in cancer patients

1989 • 185 citations

Exposure to Shear Stress Alters Endothelial Adhesiveness

1995 • 181 citations

L- and P-selectins, but not CD49d (VLA-4) integrins, mediate monocyte initial attachment to TNF-alpha-activated vascular endothelium under flow in vitro.

1996 • 157 citations

The two soluble forms of the lipopolysaccharide receptor, CD14: Characterization and release by normal human monocytes

1994 • 147 citations

Antifungal Activity Of Elutriated Human Monocytes Against Aspergillus Fumigatus Hyphae: Enhancement By Granulocyte-Macrophage Colonystimulating Factor And Interferon-a

1994 • 138 citations

Differential cytokine induction by doses of lipopolysaccharide and monophosphoryl lipid A that result in equivalent early endotoxin tolerance

1990 • 123 citations

Granulocyte-macrophage colony-stimulating factor and IFN-gamma restore the systemic TNF-alpha response to endotoxin in lipopolysaccharide-desensitized mice.

1997 • 109 citations

Effect of human recombinant cytokines on the induction of macrophage procoagulant activity

1994 • 108 citations

Tumour necrosis factor (TNF) binding proteins (soluble TNF receptor forms) with possible roles in inflammation and malignancy.

1993 • 98 citations

Granulocyte-macrophage colony-stimulating factor preferentially activates the 94-kD STAT5A and an 80-kD STAT5A isoform in human peripheral blood monocytes

1996 • 93 citations

Interleukin-10 and the Monocyte/Macrophage-Induced Inflammatory Response in Septic Shock

1995 • 91 citations

Exogenous myeloperoxidase enhances bacterial phagocytosis and intracellular killing by macrophages

1995 • 75 citations

Elevated Tumor Necrosis Factorα Production Concomitant to Elevated Prostaglandin E2 Production by Trauma Patients' Monocytes

1990 • 65 citations

Differential regulation of the mannose and SP-A receptors on macrophages

1995 • 64 citations

Induction of tissue factor expression in human monocyte/endothelium cocultures

1995 • 63 citations

Tolerance to Lipopolysaccharide in Human Blood Monocytes

1995 • 56 citations

Tissue factor expression in human leukemic cells

1996 • 54 citations

ENDOTOXIN PRETREATMENT OF HUMAN MONOCYTES ALTERS SUBSEQUENT ENDOTOXIN-TRIGGERED RELEASE OF INFLAMMATORY MEDIATORS

1995 • 51 citations

GM-CSF rapidly primes mice for enhanced cytokine production in response to LPS and TNF

1995 • 46 citations

Administration of rHuGM‐CSF activates monocyte reactive oxygen species secretion and adhesion molecule expression in vivo in patients following high‐dose chemotherapy

1995 • 45 citations

Recombinant GM-CSF reduces lung injury and mortality during neutropenic Candida sepsis

1994 • 44 citations

Activation of human endothelial cells by viable or heat-killed gram-negative bacteria requires soluble CD14

1995 • 43 citations

Effect of granulocyte-macrophage colony-stimulating factor on sepsis- induced organ injury in rats

1994 • 42 citations

The effects of rhGM-CSF on macrophage function

1993 • 40 citations

The effects of colony stimulating factors on human monocyte cell function

1995 • 36 citations

CD14 and tissue factor expression by bacterial lipopolysaccharide-stimulated bovine alveolar macrophages in vitro

1995 • 35 citations

Focal effects of mononuclear leukocyte transendothelial migration: TNF-α production by migrating monocytes promotes subsequent migration of lymphocytes

1996 • 34 citations

Granulocyte–macrophage colony-stimulating factor modulates immune function and improves survival after experimental thermal injury

1995 • 32 citations

Soluble CD14 and lipopolysaccharide-binding protein from bovine serum enable bacterial lipopolysaccharide-mediated cytotoxicity and activation of bovine vascular endothelial cells in vitro

1996 • 31 citations

Administration of recombinant human granulocyte-macrophage colony- stimulating factor after chemotherapy regulates the expression and secretion of monocyte tumor necrosis factor (TNF) and TNF receptors p55 and p75

1995 • 31 citations

Standardization of a Flow Cytometric Assay for Phagocyte Respiratory Burst Activity

1996 • 30 citations

Macrophage interactions with Candida.

1994 • 28 citations

The Beneficial Effects of Immunostimulation in Posttraumatic Sepsis

1995 • 25 citations

Treatment of sepsis and septic shock: A review

1995 • 24 citations

Tissue Factor Expression during Coculture of Endothelial Cells and Monocytes

1995 • 23 citations

Transforming Growth Factor-β1 Lowers the CD14 Content of Monocytes

1994 • 22 citations

Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) Enhances Pulmonary Defenses Against Pneumococcal Infections after Splenectomy

1996 • 21 citations

Management of septic shock

1995 • 20 citations

Role of leukotriene B₄ in the interleukin‐4‐induced human mononuclear phagocyte activation

1996 • 12 citations

Acyclic analogue of lipid A stimulates TNF-alpha and arachidonate release via a unique LPS-signaling pathway.

1994 • 9 citations

Impairment of monocytic function after influenza virus infection

1995 • 8 citations

Prevention of experimental endotoxin shock by a monocyte activator

1995 • 8 citations

Reduction of plasma fibrinolytic activity following high-dose cyclophosphamide is neutralized in vivo by GM-CSF administration.

1993 • 5 citations

GM-CSF Priming of U937 Monocytic Cells Accelerates, But Does Not Increase, Tissue Factor (TF) Expression or Procoagulant Activity (PCA) After Stimulation with Endotoxin (LPS)

1996 • 5 citations

MONOCYTES OVERCOME LYMPHOCYTE DYSFUNCTION IN INJURED ADULTS WITH ELEVATED CANDIDA ANTIGEN TITERS

1994 • 3 citations