Radiosensitivity, blood perfusion and tumour oxygenation after perflubron emulsion injection

Regional Blood Flow by Fractional Distribution of Indicators

1958 • 820 citations

Tumor hypoxia: its impact on cancer therapy

1987 • 410 citations

Tumor tissue oxygenation as evaluated by computerized-po2-histography

1990 • 255 citations

Perfluorochemical Emulsions Can Increase Tumor Radiosensitivity

1984 • 209 citations

Fluorocarbon‐Based in vivo Oxygen Transport and Delivery Systems

1991 • 139 citations

The importance of the pre-irradiation breathing times of oxygen and carbogen (5% CO2: 95% O2) on the in vivo radiation response of a murine sarcoma

1977 • 128 citations

Nicotinamide, Fluosol DA and Carbogen: a strategy to reoxygenate acutely and chronically hypoxic cells in vivo

1991 • 112 citations

Use of a perfluorochemical emulsion to improve oxygenation in a solid tumor

1985 • 110 citations

Hypoxic fractions of human tumors xenografted into mice: A review

1990 • 109 citations

Increase in pO2 and radiosensitivity of tumors by Fluosol-DA (20%) and carbogen.

1987 • 103 citations

Oxygen-carrying perfluorochemical emulsion as an adjuvant to radiation therapy in mice.

1984 • 88 citations

Relationship Between Size and Perfusion Rate of Transplanted Tumors<xref ref-type="fn" rid="fn1">2</xref>

1962 • 82 citations

Oxygen, oxygen plus carbon dioxide, and radiation therapy of a mouse mammary carcinoma

1972 • 72 citations

The effect of anaesthetics on blood perfusion in transplanted mouse tumours

1975 • 65 citations

The Radiation Response of SCCVII Tumor Cells in C3H/He Mice Varies with the Irradiation Conditions

1987 • 57 citations

Factors Affecting Hypoxic KHT Tumor Cells in Mice Breathing O₂, O₂+ CO₂, or Hyperbaric Oxygen with or without Anesthesia

1973 • 57 citations

Increase in tumor pO2 by perfluorochemicals and carbogen

1987 • 50 citations

Effect of a Perfluorochemical Emulsion on the Radiation Response of BA1112 Rhabdomyosarcomas

1987 • 47 citations

Measurement of RBE, OER, and Recovery of Potentially Lethal Damage of a 645 MeV Helium Ion Beam Using EMT6 Cells

1977 • 44 citations

The measurement of blood perfusion in experimental tumors by uptake of 86Rb.

1974 • 43 citations

Effects of dose and scheduling on growth delay of the Lewis lung carcinoma produced by the perfluorochemical emulsion, Fluosol-DA®

1986 • 41 citations

Optimization of perfluorochemical levels with radiation therapy in mice.

1989 • 39 citations

Increase in pO2 and radiosensitivity of tumors by Fluosol-DA (20%) and carbogen

1986 • 38 citations

Modulation of tumor oxygenation and radio sensitivity by a perfluorooctylbromide emulsion

1991 • 37 citations

Influence of the 100% w/v Perfluorooctyl Bromide (PFOB) Emulsion Dose on Tumour Radiosensitivity

1991 • 36 citations

Effect of duration of breathing 95% oxygen plus 5% carbon dioxide before X-irradiation on cure of C3H mammary tumor

1970 • 34 citations

Preparation and Application of Highly Concentrated Perfluoroctylbromide Fluorocarbon Emulsions

1988 • 29 citations

Does the direct measurement of oxygen tension in tumors have any adverse effects?

1992 • 28 citations

Dose fractionation studies with a murine sarcoma under conditions of air or carbogen (95% OI2 + 5% CO2) breathing

1977 • 27 citations

Comparison of the Radiobiological Properties of Human Tumour Xenografts and Rodent Tumours

1989 • 25 citations

Preclinical studies of a perfluorochemical emulsion as an adjunct to radiotherapy

1988 • 22 citations

The combination of oxygen and optimum fractionation in radiation therapy of adenocarcinoma.

1959 • 20 citations

New high O2 carrying perfluorochemical emulsions and/or carbogen: Reactions of a human tumor xenograft to irradiation

1989 • 20 citations

Keynote address: Chemical manipulations of tissue oxygenation for therapeutic benefit

1989 • 17 citations

Radiosensitization of Murine Tumors by Fluosol-DA 20%

1990 • 17 citations

Effect of Breathing 5% Carbon Dioxide and 95% Oxygen at Atmospheric Pressure on Tumour Radiocurability

1966 • 14 citations

Improvement in RBC Flux, Acidosis and Oxygenation in Tumour Microregions by Fluosol-DA 20%

1991 • 13 citations