A Tumor-selective Biotherapy With Prolonged Impact on Established Metastases Based on Cytokine Gene-engineered MSCs

A simplified system for generating recombinant adenoviruses

1998 • 3,179 citations

Impaired recruitment of bone-marrow–derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth

2001 • 1,874 citations

Migrating cancer stem cells — an integrated concept of malignant tumour progression

2005 • 1,323 citations

Human Bone Marrow–Derived Mesenchymal Stem Cells in the Treatment of Gliomas

2005 • 1,029 citations

The Dynamic in vivo Distribution of Bone Marrow-Derived Mesenchymal Stem Cells after Infusion

2001 • 927 citations

Mesenchymal Stem Cells

2001 • 882 citations

Mesenchymal Stem Cells: Potential Precursors for Tumor Stroma and Targeted-Delivery Vehicles for Anticancer Agents

2004 • 826 citations

Lymphangiogenesis and cancer metastasis

2002 • 781 citations

Trafficking of Normal Stem Cells and Metastasis of Cancer Stem Cells Involve Similar Mechanisms: Pivotal Role of the SDF‐1–CXCR4 Axis

2005 • 758 citations

Study of Telomere Length Reveals Rapid Aging of Human Marrow Stromal Cells following In Vitro Expansion

2004 • 752 citations

Human mesenchymal stem cells exert potent antitumorigenic effects in a model of Kaposi's sarcoma

2006 • 722 citations

Normal Stem Cells and Cancer Stem Cells: The Niche Matters

2006 • 665 citations

Suppression of Tumor Lymphangiogenesis and Lymph Node Metastasis by Blocking Vascular Endothelial Growth Factor Receptor 3 Signaling

2002 • 512 citations

Tumor Lymphangiogenesis

2003 • 478 citations

Clinical Trials: IL-12 Deaths: Explanation and a Puzzle

1995 • 333 citations

Tolerance and Cancer: Mechanisms of Tumor Evasion and Strategies for Breaking Tolerance

2004 • 319 citations

The role of tumor lymphangiogenesis in metastatic spread

2002 • 297 citations

Inhibition of Lymphogenous Metastasis Using Adeno-Associated Virus-Mediated Gene Transfer of a Soluble VEGFR-3 Decoy Receptor

2005 • 261 citations

Intratumoral lymphatics are essential for the metastatic spread and prognosis in squamous cell carcinomas of the head and neck region.

2003 • 246 citations

Complete and Specific Inhibition of Adult Lymphatic Regeneration by a Novel VEGFR-3 Neutralizing Antibody

2005 • 242 citations

Interleukin-15 rescues tolerant CD8+ T cells for use in adoptive immunotherapy of established tumors

2006 • 234 citations

Isolation of a Highly Clonogenic and Multipotential Subfraction of Adult Stem Cells from Bone Marrow Stroma

2004 • 219 citations

Mesenchymal stem cells (MSC) as therapeutic cytoreagents for gene therapy

2005 • 207 citations

Differential in vivo and in vitro expression of vascular endothelial growth factor (VEGF)-C and VEGF-D in tumors and its relationship to lymphatic metastasis in immunocompetent rats.

2003 • 188 citations

Lymphatic function, lymphangiogenesis, and cancer metastasis

2001 • 185 citations

Lymphangiogenesis Correlates with Lymph Node Metastasis, Prognosis, and Angiogenic Phenotype in Human Non–Small Cell Lung Cancer

2005 • 174 citations

High LYVE-1–Positive Lymphatic Vessel Numbers Are Associated with Poor Outcome in Breast Cancer

2004 • 172 citations

Lymphatic vessels in cancer metastasis: bridging the gaps

2006 • 170 citations

Peritumor Lymphatics Induced by Vascular Endothelial Growth Factor-C Exhibit Abnormal Function

2004 • 152 citations

Functional Imaging of Cancer with Emphasis on Molecular Techniques

2007 • 131 citations

IFN-γ and Fas/FasL are required for the antitumor and antiangiogenic effects of IL-12/pulse IL-2 therapy

2001 • 130 citations

Monoclonal antibodies to vascular endothelial growth factor‐D block its interactions with both VEGF receptor‐2 and VEGF receptor‐3

2000 • 113 citations

Intratumoral Lymphatics and Lymph Node Metastases in Papillary Thyroid Carcinoma

2003 • 107 citations

IFN-γ and Fas/FasL are required for the antitumor and antiangiogenic effects of IL-12/pulse IL-2 therapy

2001 • 106 citations

Prophylaxis against carcinogenesis in three kinds of unestablished tumor models via IL12-gene-engineered MSCs

2006 • 79 citations

Cells as Vehicles for Cancer Gene Therapy: The Missing Link Between Targeted Vectors and Systemic Delivery?

2002 • 77 citations

In vivo gene transfer of CD40 ligand into colon cancer cells induces local production of cytokines and chemokines, tumor eradication and protective antitumor immunity

2000 • 75 citations

Bone marrow stromal cells as a vehicle for gene transfer

1999 • 71 citations

A gene therapy for cancer based on the angiogenesis inhibitor, vasostatin

2002 • 71 citations

Enhanced Tumor-Specific Long-Term Immunity of Hemaggluttinating Virus of Japan-Mediated Dendritic Cell-Tumor Fused Cell Vaccination by Coadministration with CpG Oligodeoxynucleotides

2004 • 48 citations

IL-12 suppresses the expression of ocular immunoinflammatory lesions by effects on angiogenesis

2002 • 42 citations

The challenge of vector development in gene therapy

1999 • 26 citations

99mTc–Evans Blue Dye for Mapping Contiguous Lymph Node Sequences and Discriminating the Sentinel Lymph Node in an Ovine Model

2006 • 23 citations

Uncommon Manifestations of Common Malignancies

2004 • 21 citations

Therapeutic Modulation of Akt Activity and Antitumor Efficacy of Interleukin-12 Against Orthotopic Murine Neuroblastoma

2006 • 15 citations

Capacity of murine IL‐12 to inhibit the development of primary melanoma tumors and to prevent lung metastases in the melanoma‐challenged mice

2002 • 8 citations

Mesenchymal stem cells as delivery systems for cancer and leukemia gene therapy

2004 • 4 citations

Mesenchymal stem cells as delivery systems for cancer and leukemia gene therapy

2004 • 3 citations