Autoregulation of the Human Liver X Receptor α Promoter

Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor

1994 • 3,477 citations

15-Deoxy-Δ12,14-Prostaglandin J2 is a ligand for the adipocyte determination factor PPARγ

1995 • 2,857 citations

A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation

1995 • 2,036 citations

Oxidized LDL Regulates Macrophage Gene Expression through Ligand Activation of PPARγ

1998 • 1,819 citations

PPARγ Promotes Monocyte/Macrophage Differentiation and Uptake of Oxidized LDL

1998 • 1,771 citations

An oxysterol signalling pathway mediated by the nuclear receptor LXRα

1996 • 1,678 citations

Low Density Lipoprotein Oxidation and Its Pathobiological Significance

1997 • 1,642 citations

Role of LXRs in control of lipogenesis

2000 • 1,623 citations

Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRα and LXRβ

2000 • 1,619 citations

Cholesterol and Bile Acid Metabolism Are Impaired in Mice Lacking the Nuclear Oxysterol Receptor LXRα

1998 • 1,408 citations

A PPARγ-LXR-ABCA1 Pathway in Macrophages Is Involved in Cholesterol Efflux and Atherogenesis

2001 • 1,287 citations

Regulation of Absorption and ABC1-Mediated Efflux of Cholesterol by RXR Heterodimers

2000 • 1,285 citations

Activation of the Nuclear Receptor LXR by Oxysterols Defines a New Hormone Response Pathway

1997 • 1,207 citations

PPAR-α and PPAR-γ activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway

2001 • 1,134 citations

LXR, a nuclear receptor that defines a distinct retinoid response pathway.

1995 • 1,089 citations

A selective peroxisome proliferator-activated receptor δ agonist promotes reverse cholesterol transport

2001 • 1,050 citations

Cell Biology of Atherosclerosis

1995 • 982 citations

Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXRα

2000 • 965 citations

Sterol-dependent Transactivation of theABC1 Promoter by the Liver X Receptor/Retinoid X Receptor

2000 • 962 citations

The Role of Orphan Nuclear Receptors in the Regulation of Cholesterol Homeostasis

2000 • 734 citations

LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes

2001 • 643 citations

CLA-1/SR-BI Is Expressed in Atherosclerotic Lesion Macrophages and Regulated by Activators of Peroxisome Proliferator-Activated Receptors

2000 • 424 citations

ABC1 Gene Expression and ApoA-I-Mediated Cholesterol Efflux Are Regulated by LXR

2000 • 407 citations

Human White/Murine ABC8 mRNA Levels Are Highly Induced in Lipid-loaded Macrophages

2000 • 386 citations

The LXRs: a new class of oxysterol receptors

1998 • 358 citations

Identification of the DNA Binding Specificity and Potential Target Genes for the Farnesoid X-activated Receptor

2000 • 268 citations

Expression of sterol regulatory element-binding protein 1c (SREBP-1c) mRNA in rat hepatoma cells requires endogenous LXR ligands

2001 • 240 citations

Cross-Talk between Fatty Acid and Cholesterol Metabolism Mediated by Liver X Receptor-α

2000 • 187 citations

Pharmacophore Analysis of the Nuclear Oxysterol Receptor LXRα

2001 • 123 citations

Structural characterisation of the mouse nuclear oxysterol receptor genes LXRα and LXRβ

2000 • 88 citations