Norepinephrine Infusion into Nucleus Basalis Elicits Microarousal in Desflurane-anesthetized Rats

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

The brainweb: Phase synchronization and large-scale integration

2001 • 4,616 citations

An information integration theory of consciousness.

2004 • 1,455 citations

CENTRAL CHOLINERGIC SYSTEMS AND COGNITION

1997 • 1,328 citations

General anaesthesia: from molecular targets to neuronal pathways of sleep and arousal

2008 • 1,192 citations

Consciousness and Anesthesia

2008 • 1,174 citations

General Anesthesia, Sleep, and Coma

2010 • 1,168 citations

Acetylcholine in mind: a neurotransmitter correlate of consciousness?

1999 • 750 citations

Cellular bases of neocortical activation: modulation of neural oscillations by the nucleus basalis and endogenous acetylcholine

1992 • 590 citations

The nature of arousal in sleep

2004 • 501 citations

Induction of a physiological memory in the cerebral cortex by stimulation of the nucleus basalis.

1996 • 479 citations

Acetylcholine Liberation from Cerebral Cortex during Paradoxical (REM) Sleep

1971 • 427 citations

Integrated Information in Discrete Dynamical Systems: Motivation and Theoretical Framework

2008 • 394 citations

GABAergic and other noncholinergic basal forebrain neurons, together with cholinergic neurons, project to the mesocortex and isocortex in the rat

1997 • 319 citations

Projections of cholinergic and non-cholinergic neurons of the brainstem core to relay and associational thalamic nuclei in the cat and macaque monkey

1988 • 305 citations

gamma-Aminobutyric acid-containing basal forebrain neurons innervate inhibitory interneurons in the neocortex.

1992 • 293 citations

Activity, modulation and role of basal forebrain cholinergic neurons innervating the cerebral cortex

2004 • 292 citations

Invariant Reversible QEEG Effects of Anesthetics

2001 • 275 citations

Magnocellular Nuclei of the Basal Forebrain: Substrates of Sleep and Arousal Regulation

1995 • 272 citations

The Anesthetic Cascade

2005 • 257 citations

Multiple output pathways of the basal forebrain: organization, chemical heterogeneity, and roles in vigilance

2000 • 255 citations

Sleep, Anesthesiology, and the Neurobiology of Arousal State Control

2005 • 234 citations

Alpha4beta2 Neuronal Nicotinic Acetylcholine Receptors in the Central Nervous System Are Inhibited by Isoflurane and Propofol, but alpha7-type Nicotinic Acetylcholine Receptors Are Unaffected

1997 • 228 citations

Role of endogenous sleep‐wake and analgesic systems in anesthesia

2008 • 225 citations

Impaired thalamocortical connectivity in humans during general-anesthetic-induced unconsciousness

2003 • 225 citations

Thalamic Microinjection of Nicotine Reverses Sevoflurane-induced Loss of Righting Reflex in the Rat

2007 • 224 citations

BEHAVIOR OF CHRONIC DECEREBRATE RATS

1964 • 218 citations

Differential Dynamic of Action on Cortical and Subcortical Structures of Anesthetic Agents during Induction of Anesthesia

2007 • 207 citations

Volatile anesthetics disrupt frontal-posterior recurrent information transfer at gamma frequencies in rat

2005 • 193 citations

Physostigmine Reverses Propofol-induced Unconsciousness and Attenuation of the Auditory Steady State Response and Bispectral Index in Human Volunteers

2000 • 175 citations

Neocortex is the major target of sedative concentrations of volatile anaesthetics: strong depression of firing rates and increase of GABA_A receptor‐mediated inhibition

2005 • 172 citations

Differential modulation of high-frequency gamma-electroencephalogram activity and sleep-wake state by noradrenaline and serotonin microinjections into the region of cholinergic basalis neurons.

1998 • 165 citations

Modification of neocortical acetylcholine release and electroencephalogram desynchronization due to brainstem stimulation by drugs applied to the basal forebrain

1994 • 158 citations

Mechanism of Anesthesia Revealed by Shunting Actions of Isoflurane on Thalamocortical Neurons

1999 • 156 citations

The role of basal forebrain neurons in tonic and phasic activation of the cerebral cortex

1999 • 155 citations

Anterior Shift of the Dominant EEG Rhythm during Anesthesia in the Java Monkey

1977 • 154 citations

Effects of glutamate agonist versus procaine microinjections into the basal forebrain cholinergic cell area upon gamma and theta EEG activity and sleep–wake state

2000 • 138 citations

Hierarchy of micro-arousals and the microstructure of sleep

1998 • 132 citations

The Septohippocampal System Participates in General Anesthesia

2002 • 127 citations

Neurotensin-induced bursting of cholinergic basal forebrain neurons promotes gamma and theta cortical activity together with waking and paradoxical sleep.

2000 • 125 citations

Noradrenergic Modulation of Cholinergic Nucleus Basalis Neurons Demonstrated byin vitroPharmacological and Immunohistochemical Evidence in the Guinea-pig Brain

1995 • 116 citations

The effects of anesthetics on brain activity and cognitive function

2005 • 111 citations

Basal forebrain stimulation facilitates tone-evoked responses in the auditory cortex of awake rat

1993 • 107 citations

Are neocortical gamma waves related to consciousness?

2000 • 106 citations

Basal Forebrain Histaminergic Transmission Modulates Electroencephalographic Activity and Emergence from Isoflurane Anesthesia

2009 • 91 citations

Isoflurane induces dose-dependent changes of thalamic somatosensory information transfer

1999 • 89 citations

The G. L. Brown lecture. Adventures in anaesthesia

1991 • 86 citations

Cholinergic Reversal of Isoflurane Anesthesia in Rats as Measured by Cross-approximate Entropy of the Electroencephalogram

2003 • 85 citations

The cholinergic nucleus basalis: A key structure in neocortical arousal

1989 • 85 citations

Arousals without awakening—Dynamic aspect of sleep

1993 • 77 citations

Modulation of forebrain electroencephalographic activity in halothane-anesthetized rat via actions of noradrenergic beta-receptors within the medial septal region.

1996 • 70 citations

Acetylcholine Release from the Central Nervous System: A 50-Year Retrospective

2005 • 70 citations

Halothane decreases pontine acetylcholine release and increases EEG spindles

1994 • 66 citations

Differential Effects of Isoflurane on High-frequency and Low-frequency γ Oscillations in the Cerebral Cortex and Hippocampus in Freely Moving Rats

2011 • 63 citations

Micro-arousals during nocturnal sleep.

1979 • 62 citations

Involvement of the Basal Cholinergic Forebrain in the Mediation of General (Propofol) Anesthesia

2008 • 61 citations

Antagonism of sevoflurane anaesthesia by physostigmine: effects on the auditory steady-state response and bispectral index †

2003 • 56 citations

Effect of volatile anesthetics on interhemispheric EEG cross-approximate entropy in the rat

2002 • 50 citations

Contributions of GABAergic and glutamatergic mechanisms to isoflurane-induced suppression of thalamic somatosensory information transfer

2006 • 47 citations

Acetylcholine Concentrations and Turnover in Rat Brain Structures during Anesthesia with Halothane, Enflurane, and Ketamine

1978 • 44 citations

Cross-approximate entropy of cortical local field potentials quantifies effects of anesthesia - a pilot study in rats

2010 • 38 citations

Effects of isoflurane on in vivo release of acetylcholine in the rat cerebral cortex and striatum

1997 • 38 citations

The effects of anaesthesia and hypothermia on interstitial concentrations of acetylcholine and choline in rat striatum

1991 • 37 citations

[Phases of spontaneous transitory activation during normal sleep in humans].

1971 • 37 citations

Central Cholinergic Depression Reduces MAC for Isoflurane in Rats

1991 • 35 citations

Sleep is differently modulated by basal forebrain GABA_A and GABA_B receptors

2001 • 35 citations

Mesopontine tegmental anesthesia area projects independently to the rostromedial medulla and to the spinal cord

2007 • 19 citations

Cholinergic mechanisms mediating anesthetic induced altered states of consciousness

2004 • 16 citations

[Effect of isoflurane anesthesia on norepinephrine metabolism in rat brain].

1992 • 5 citations