Delineation of the Protein Domains Responsible for SYT, SSX, and SYT-SSX Nuclear Localization

Nuclear targeting sequences — a consensus?

1991 • 1,908 citations

Chromosomal translocations in human cancer

1994 • 1,551 citations

Structure and Function in the Nucleus

1998 • 925 citations

Identification of novel genes, SYT and SSX, involved in the t(X;18)(p11.2;q11.2) translocation found in human synovial sarcoma

1994 • 748 citations

Factor required for mammalian spliceosome assembly is localized to discrete regions in the nucleus

1990 • 723 citations

Retinoic acid regulates aberrant nuclear localization of PML-RARα in acute promyelocytic leukemia cells

1994 • 668 citations

SYT–SSXGene Fusion as a Determinant of Morphology and Prognosis in Synovial Sarcoma

1998 • 646 citations

Histone acetylases and deacetylases in cell proliferation

1999 • 598 citations

Nuclear foci of mammalian Rad51 recombination protein in somatic cells after DNA damage and its localization in synaptonemal complexes.

1995 • 556 citations

Fusion of SYT to two genes, SSX1 and SSX2, encoding proteins with homology to the Kruppel-associated box in human synovial sarcoma.

1995 • 467 citations

THE POLYCOMB AND TRITHORAX GROUP PROTEINS OF DROSOPHILA: Trans-Regulators of Homeotic Gene Function

1995 • 390 citations

In vivo binding pattern of a trans-regulator of homoeotic genes in Drosophila melanogaster

1989 • 302 citations

Identification of a novel nuclear domain.

1991 • 285 citations

The Human Polycomb Group Complex Associates with Pericentromeric Heterochromatin to Form a Novel Nuclear Domain

1998 • 279 citations

Interaction of SP100 with HP1 proteins: A link between the promyelocytic leukemia-associated nuclear bodies and the chromatin compartment

1998 • 269 citations

A monoclonal antibody recognizing nuclear matrix-associated nuclear bodies

1992 • 258 citations

SSX: A multigene family with several members transcribed in normal testis and human cancer

1997 • 242 citations

Involvement of chromosome X in primary cytogenetic change in human neoplasia: nonrandom translocation in synovial sarcoma.

1987 • 237 citations

Characterization of Interactions between the Mammalian Polycomb-Group Proteins Enx1/EZH2 and EED Suggests the Existence of Different Mammalian Polycomb-Group Protein Complexes

1998 • 219 citations

Identification of two alternative fusion genes, SYT-SSX1 and SYT-SSX2, in t(X; 18)(p11.2;q11.2)-positive synoviaol sarcomas

1995 • 213 citations

Fusion of the transcription factor TFE3 gene to a novel gene, PRCC , in t(X;1)(p11;q21)-positive papillary renal cell carcinomas

1996 • 199 citations

RING1 Is Associated with the Polycomb Group Protein Complex and Acts as a Transcriptional Repressor

1997 • 189 citations

Expression ofSSX genes in human tumors

1998 • 181 citations

Chromatin components as part of a putative transcriptional repressing complex

1998 • 179 citations

Molecular diagnosis of synovial sarcoma and characterization of a variant SYT-SSX2 fusion transcript.

1995 • 159 citations

Truncated WT1 mutants alter the subnuclear localization of the wild-type protein.

1995 • 158 citations

Relocation of the carboxyterminal part of CAN from the nuclear envelope to the nucleus as a result of leukemia-specific chromosome rearrangements.

1995 • 156 citations

Functional Domains of the SYT and SYT-SSX Synovial Sarcoma Translocation Proteins and Co-Localization with the SNF Protein BRM in the Nucleus

1999 • 153 citations

Heterogeneous expression of the SSX cancer/testis antigens in human melanoma lesions and cell lines.

2000 • 153 citations

The SYT protein involved in the t(X;18) synovial sarcoma translocation is a transcriptional activator localised in nuclear bodies

1997 • 147 citations

Characterization of a second highly conserved B-type lamin present in cells previously thought to contain only a single B-type lamin

1990 • 145 citations

A KRAB-related domain and a novel transcription repression domain in proteins encoded by SSX genes that are disrupted in human sarcomas

1998 • 144 citations

Chromatin-silencing mechanisms in Drosophila maintain patterns of gene expression

1997 • 137 citations

Transcriptional repression by Drosophila and mammalian Polycomb group proteins in transfected mammalian cells.

1994 • 123 citations

RING1 Interacts with Multiple Polycomb-Group Proteins and Displays Tumorigenic Activity

1999 • 122 citations

SSX and the synovial-sarcoma-specific chimaeric protein SYT-SSX co-localize with the human Polycomb group complex

1999 • 115 citations

Nuclear localization of SYT, SSX and the synovial sarcoma-associated SYT-SSX fusion proteins

1997 • 104 citations

Gene fusions encoding chimaeric transcription factors in solid tumours

1996 • 97 citations

A role for heterodimerization in nuclear localization of a homeodomain protein

1998 • 97 citations

Site-Directed Mutagenesis: A Two-Step Method Using PCR and Dpn I

1997 • 89 citations

Distinct Xp11.2 breakpoint regions in synovial sarcoma revealed by metaphase and interphase FISH: Relationship to histologic subtypes

1994 • 89 citations

The trithorax-group and Polycomb-group chromatin modifiers: implications for disease

1999 • 79 citations

Nuclear Domains Involved in RNA Synthesis, RNA Processing, and Replication

1996 • 57 citations

Isolation and characterization of the mouse homolog of SYT, a gene implicated in the development of human synovial sarcomas.

1996 • 51 citations

Transcriptional regulation: SWItching circuitry

1999 • 49 citations

A novel Krüppel-associated box containing the SSX gene (SSX3) on the human X chromosome is not implicated in t(X;18)-positive synovial sarcomas

1996 • 49 citations

Two versatile eukaryotic expression vectors permitting epitope tagging, radiolabelling and nuclear localisation of expressed proteins

1996 • 43 citations

Identification of the nuclear localization signal of mouse DNA primase: nuclear transport of p46 subunit is facilitated by interaction with p54 subunit

1996 • 41 citations

The localization of the HRX/ALL1 protein to specific nuclear subdomains is altered by fusion with its eps15 translocation partner.

1997 • 40 citations

Nuclear translocation of Fos is stimulated by interaction with Jun through the leucine zipper

1999 • 33 citations

Diffusion of Proteins Across the Nuclear Envelope of HeLa Cells

1998 • 24 citations

Masked t(X;18)(p11;q11) in a biphasic synovial sarcoma revealed by FISH and RT‐PCR

1998 • 22 citations

Masked t(X;18)(p11;q11) in a biphasic synovial sarcoma revealed by FISH and RT-PCR

1998 • 22 citations