Quantitative evaluation of the potencies of GABA‐receptor agonists and antagonists using the rat hippocampal slice preparation

SOME QUANTITATIVE USES OF DRUG ANTAGONISTS

1959 • 3,948 citations

(–)Baclofen decreases neurotransmitter release in the mammalian CNS by an action at a novel GABA receptor

1980 • 1,091 citations

3H-baclofen and 3H-GABA bind to bicuculline-insensitive GABAB sites in rat brain

1981 • 1,044 citations

GABA‐Benzodiazepine‐Barbiturate Receptor Interactions

1981 • 910 citations

Immunocytochemical localization of glutamic acid decarboxylase in neuronal somata following colchicine inhibition of axonal transport

1978 • 633 citations

Pharmacological evidence for two kinds of GABA receptors on rat hippocampal pyramidal cells studied in vitro

1982 • 527 citations

Comparison of the action of baclofen with gamma‐aminobutyric acid on rat hippocampal pyramidal cells in vitro.

1985 • 488 citations

GABAB-receptor-activated K+ current in voltage-clamped CA3 pyramidal cells in hippocampal cultures.

1985 • 468 citations

Bicuculline-insensitive gaba receptors on peripheral autonomic nerve terminals

1981 • 376 citations

Neurotransmitters, seizures and epilepsy

1982 • 353 citations

Direct hyperpolarizing action of baclofen on hippocampal pyramidal cells

1984 • 342 citations

Glutamate decarboxylase immunoreactivity in the hippocampus of the cat: distribution of immunoreactive synaptic terminals with special reference to the axon initial segment of pyramidal neurons

1983 • 219 citations

TWO TYPES OF γ‐AMINOBUTYRIC ACID RECEPTOR ON EMBRYONIC SENSORY NEURONES

1981 • 213 citations

Identified axo-axonic cells are immunoreactive for GABA in the hippocampus visual cortex of the cat

1985 • 212 citations

gamma-aminobutyric acid B receptors are negatively coupled to adenylate cyclase in brain, and in the cerebellum these receptors may be associated with granule cells.

1984 • 202 citations

Baclofen: 10 years on

1982 • 201 citations

Synaptic Excitation May Activate a Calcium-Dependent Potassium Conductance in Hippocampal Pyramidal Cells

1981 • 193 citations

γ-Aminobutyric acid-induced depression of calcium currents of chick sensory neurons

1985 • 147 citations

Problems in GABA Research from Brain to Bacteria

1983 • 144 citations

Baclofen selectively inhibits transmission at synapses made by axons of CA3 pyramidal cells in the hippocampal slice.

1982 • 141 citations

Classification of some GABA antagonists with regard to site of action and potency in slices of rat cuneate nucleus

1982 • 109 citations

[³H]Bicuculline Methochloride Binding to Low‐Affinity γ‐Aminobutyric Acid Receptor Sites

1983 • 108 citations

GABAB receptor modulation of adenylate cyclase activity in rat brain slices.

1985 • 105 citations

PRESYNAPTIC ACTIONS OF β‐AMINOBUTYRIC ACID AND SOME ANTAGONISTS IN A SLICE PREPARATION OF CUNEATE NUCLEUS

1978 • 96 citations

GABA Analogues Activate Channels of Different Duration on Cultured Mouse Spinal Neurons

1981 • 94 citations

GABAB receptors and norepinephrine-stimulated cAMP production in rat brain cortex

1984 • 92 citations

The blocking action of baclofen on excitatory transmission in the rat hippocampal slice

1982 • 88 citations

DISTINCTION BETWEEN THE EFFECTS OF BARBITURATES, BENZODIAZEPINES AND PHENYTOIN ON RESPONSES TO γ‐AMINOBUTYRIC ACID RECEPTOR ACTIVATION AND ANTAGONISM BY BICUCULLINE AND PICROTOXIN

1981 • 76 citations

γ‐AMINOBUTYRIC ACID AGONISTS: AN in vitro COMPARISON BETWEEN DEPRESSION OF SPINAL SYNAPTIC ACTIVITY AND DEPOLARIZATION OF SPINAL ROOT FIBRES IN THE RAT

1980 • 75 citations

Pitrazepin, a novel GABAA antagonist

1984 • 63 citations

GABA receptor agonists: Pharmacological spectrum and therapeutic actions

1985 • 57 citations

Effects of baclofen on synaptically‐induced cell firing in the rat hippocampal slice

1983 • 46 citations

Characterization of the Binding of the GABA Agonist [³H]Piperidine‐4‐Sulphonic Acid to Bovine Brain Synaptic Membranes

1981 • 45 citations

INFLUENCE OF CELLULAR TRANSPORT ON THE INTERACTION OF AMINO ACIDS WITH γ‐AMINOBUTYRIC ACID (GABA)‐RECEPTORS IN THE ISOLATED OLFACTORY CORTEX OF THE GUINEA‐PIG

1980 • 43 citations

Desensitization of prostacyclin responsiveness in a neuronal hybrid cell line: selective loss of high affinity receptors

1985 • 38 citations

Modulation of adenylate cyclase activity by GABAB receptors

1984 • 24 citations

The use of brain slices in central nervous system pharmacology.

1983 • 22 citations

Inhibition of GABA uptake potentiates the conductance increase produced by GABA‐mimetic compounds on single neurones in isolated olfactory cortex slices of the guinea‐pig

1984 • 18 citations

THE UPTAKE OF GABA INTO RAT SPINAL ROOTS

1974 • 13 citations

The calcium dependency of mucus glycoconjugate secretion by canine tracheal explants

1984 • 13 citations

The neuropharmacology of a novel gamma-aminobutyric acid analog, kojic amine.

1979 • 7 citations