Activation of protein kinase A acutely inhibits and phosphorylates Na/H exchanger NHE-3.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

[11] Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates

1991 • 1,463 citations

[3] Protein kinase phosphorylation site sequences and consensus specificity motifs: Tabulations

1991 • 1,036 citations

Molecular cloning, primary structure, and expression of the human growth factor-activatable antiporter

1989 • 774 citations

Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel

1991 • 658 citations

Molecular cloning of putative members of the Na/H exchanger gene family. cDNA cloning, deduced amino acid sequence, and mRNA tissue expression of the rat Na/H exchanger NHE-1 and two structurally related proteins.

1992 • 585 citations

The plasma membrane sodium-hydrogen exchanger and its role in physiological and pathophysiological processes.

1985 • 506 citations

Growth Factors Induce Phosphorylation of the Na ⁺ /H ⁺ Antiporter, a Glycoprotein of 110 kD

1990 • 452 citations

Expression of NHE-3 in the apical membrane of rat renal proximal tubule and thick ascending limb

1995 • 366 citations

Cloning and sequencing of a rabbit cDNA encoding an intestinal and kidney-specific Na+/H+ exchanger isoform (NHE-3).

1992 • 347 citations

NHE3: a Na+/H+ exchanger isoform of renal brush border

1993 • 345 citations

Angiotensin II directly stimulates sodium transport in rabbit proximal convoluted tubules.

1984 • 338 citations

Phosphorylation of the cystic fibrosis transmembrane conductance regulator.

1992 • 324 citations

Phosphorylation of the catalytic subunit of Na+,K(+)-ATPase inhibits the activity of the enzyme.

1991 • 307 citations

Protein kinase A (PKA) still activates CFTR chloride channel after mutagenesis of all 10 PKA consensus phosphorylation sites

1993 • 296 citations

The Na+/H+ antiporter cytoplasmic domain mediates growth factor signals and controls "H(+)-sensing".

1992 • 291 citations

Heterologous expression and functional properties of amiloride high affinity (NHE-1) and low affinity (NHE-3) isoforms of the rat Na/H exchanger

1993 • 267 citations

Kinetics and regulation of three cloned mammalian Na+/H+ exchangers stably expressed in a fibroblast cell line.

1993 • 235 citations

Primary structure and functional expression of a novel gastrointestinal isoform of the rat Na/H exchanger

1993 • 221 citations

Cloning and expression of a rabbit cDNA encoding a serum-activated ethylisopropylamiloride-resistant epithelial Na+/H+ exchanger isoform (NHE-2)

1993 • 215 citations

Dopamine inhibits Na(+)-H+ exchanger activity in renal BBMV by stimulation of adenylate cyclase

1990 • 206 citations

Angiotensin II stimulates early proximal bicarbonate absorption in the rat by decreasing cyclic adenosine monophosphate.

1989 • 201 citations

Alpha-thrombin, epidermal growth factor, and okadaic acid activate the Na+/H+ exchanger, NHE-1, by phosphorylating a set of common sites.

1991 • 189 citations

Phosphorylation of the Na,K-ATPase alpha-subunit by protein kinase A and C in vitro and in intact cells. Identification of a novel motif for PKC-mediated phosphorylation.

1994 • 172 citations

Growth factor activation and “H(+)-sensing” of the Na+/H+ exchanger isoform 1 (NHE1). Evidence for an additional mechanism not requiring direct phosphorylation.

1994 • 166 citations

Identification of the phosphorylation site for cAMP-dependent protein kinase on Na+,K(+)-ATPase and effects of site-directed mutagenesis.

1994 • 149 citations

Cloning and expression of a cAMP-activated Na+/H+ exchanger: evidence that the cytoplasmic domain mediates hormonal regulation.

1992 • 142 citations

Functional characteristics of a cloned epithelial Na+/H+ exchanger (NHE3): resistance to amiloride and inhibition by protein kinase C.

1993 • 139 citations

Angiotensin II: a potent regulator of acidification in the rat early proximal convoluted tubule.

1987 • 138 citations

Glucocorticoid stimulation of ileal Na+ absorptive cell brush border Na+/H+ exchange and association with an increase in message for NHE-3, an epithelial Na+/H+ exchanger isoform.

1993 • 125 citations

Parathyroid hormone inhibition of Na+-H+ antiporter activity in a cultured renal cell line

1986 • 124 citations

Impaired cell volume regulation in Na(+)-H+ exchange-deficient mutants

1989 • 124 citations

CAMP-mediated inhibition of the renal brush border membrane Na+-H+ exchanger requires a dissociable phosphoprotein cofactor.

1993 • 121 citations

Angiotensin II stimulation of Na(+)-H+ exchange in proximal tubule cells

1990 • 119 citations

Parathyroid hormone and dibutyryl cAMP inhibit Na+/H+ exchange in renal brush border vesicles

1985 • 118 citations

Differential regulation of Na/H antiporter by acid in renal epithelial cells and fibroblasts.

1991 • 116 citations

Phosphorylation of the glucose transporter in rat adipocytes. Identification of the intracellular domain at the carboxyl terminus as a target for phosphorylation in intact-cells and in vitro.

1990 • 110 citations

Alpha 2 adrenergic agonists stimulate Na+-H+ antiport activity in the rabbit renal proximal tubule.

1987 • 96 citations

Acid incubation increases NHE-3 mRNA abundance in OKP cells

1995 • 92 citations

cAMP-associated inhibition of Na+-H+ exchanger in rabbit kidney brush-border membranes

1987 • 75 citations

Endothelin-1 stimulates the Na+/H+ and Na+/HCO3- transporters in rabbit renal cortex

1992 • 71 citations

Effect of glucocorticoids on renal cortical NHE-3 and NHE-1 mRNA

1994 • 70 citations

Functional expression of a human Na+/H+ antiporter gene transfected into antiporter-deficient mouse L cells.

1986 • 70 citations

Ontogeny of rabbit renal cortical NHE3 and NHE1: effect of glucocorticoids

1995 • 66 citations

Bicarbonate transport by proximal tubules: effect of parathyroid hormone and dibutyryl cyclic AMP

1980 • 63 citations

Renal Acidification Mechanisms

2012 • 61 citations

Alpha2-adrenoceptors and cellular cAMP levels in single nephron segments from the rat

1985 • 57 citations

Separate regulatory control of apical and basolateral Na+/H+ exchange in renal epithelial cells

1989 • 56 citations

Effects of endothelin on rat renal proximal tubule Na(+)-Pi cotransport and Na+/H+ exchange

1994 • 47 citations

Cyclic adenosine monophosphate acutely inhibits and chronically stimulates Na/H antiporter in OKP cells.

1993 • 46 citations

The cytoplasmic domain of the Na+/H+ exchangers (NHEs) dictates the nature of the hormonal response: behavior of a chimeric human NHE1/trout beta NHE antiporter.

1994 • 45 citations

Role of cytoplasmic domain of the Na+/H+ exchanger in hormonal activation.

1993 • 41 citations

Adrenergic control of bicarbonate absorption in the proximal convoluted tubule of the rat kidney

1980 • 41 citations

Alpha and beta adrenergic agonists stimulate water absorption in the rat proximal tubule

1982 • 38 citations

Role of protein phosphorylation and dephosphorylation in activation and desensitization of the cAMP-dependent Na+/H+ antiport.

1993 • 34 citations

The Signal Transducer for the Dopamine-1 Regulated Sodium Transport in Renal Cortical Brush Border Membrane Vesicles

1990 • 31 citations

G protein-mediated inhibition of phospholipase C activity in a solubilized membrane preparation.

1993 • 29 citations

Effect of dopamine on phosphate reabsorption in isolated perfused rabbit proximal tubules.

1983 • 28 citations

Molecular biology and hormonal regulation of vertebrate Na+/H+ exchanger isoforms.

1993 • 28 citations

Regulation of renal Na(+)-H+ exchanger by cAMP-dependent protein kinase

1990 • 25 citations

Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel

1991 • 15 citations

Identification of a putative Na(+)-H+ exchanger regulatory cofactor in rabbit renal BBM

1990 • 14 citations