Deficiency of active natural killer cells in the Chediak-Higashi syndrome. Localization of the defect using a single cell cytotoxicity assay.

A rapid method for the isolation of functional thymus‐derived murine lymphocytes

1973 • 4,203 citations

Natural Cell-Mediated Immunity

1978 • 1,063 citations

Natural Killer Cells: Characteristics and Regulation of Activity

1979 • 582 citations

The Chediak-Higashi syndrome: studies in four patients and a review of the literature.

1972 • 398 citations

Abnormal Bactericidal, Metabolic, and Lysosomal Functions of Chediak-Higashi Syndrome Leukocytes

1972 • 372 citations

Mechanism of cell-mediated cytotoxicity at the single cell level. I. Estimation of cytotoxic T lymphocyte frequency and relative lytic efficiency.

1979 • 217 citations

Recycling and target binding capacity of human natural killer cells.

1981 • 196 citations

Chediak-Higashi gene in humans. I. Impairment of natural - killer function

1980 • 193 citations

Interferon activation of "pre-spontaneous killer" (pre-SK) cells and alteration in kinetics of lysis of both "pre-SK" and active SK cells.

1980 • 168 citations

Mode of action of interferon-mediated modulation of natural killer cytotoxic activity: recruitment of pre-NK cells and enhanced kinetics of lysis.

1980 • 151 citations

Impaired microtubule function correctable by cyclic GMP and cholinergic agonists in the Chediak-Higashi syndrome.

1976 • 141 citations

Chediak-Higashi syndrome. Observations on the nature of the associated malignancy.

1966 • 115 citations

Chediak-Higashi gene in humans. II. The selectivity of the defect in natural- killer and antibody-dependent cell-mediated cytotoxicity function

1980 • 110 citations

Mechanisms of antibody-dependent cellular cytotoxicity: the use of effector cells from chronic granulomatous disease patients as investigative probes.

1980 • 80 citations

Activation of human NKCC by moderate exercise: increased frequency of NK cells with enhanced capability of effector--target lytic interactions.

1981 • 67 citations

The dual interaction of prostaglandin E2 (PGE2) and interferon (IFN) on NK lytic activation: enhanced capacity of effector-target lytic interactions (recycling) and blockage of pre-NK cell recruitment.

1981 • 50 citations

Mechanism of cell-mediated cytotoxicity at the single cell level. III. Evidence that cytotoxic T lymphocytes lyse both antigen-specific and -nonspecific targets pretreated with lectins or periodate.

1981 • 44 citations