Natural Killer Cells: Characteristics and Regulation of Activity

Natural cytotoxic reactivity of mouse lymphoid cells against syngeneic and allogeneic tumors. I. Distribution of reactivity and specificity

1975 • 1,308 citations

„Natural”︁ killer cells in the mouse. II. Cytotoxic cells with specificity for mouse Moloney leukemia cells. Characteristics of the killer cell

1975 • 1,090 citations

Natural cytotoxic reactivity of mouse lymphoid cells against syngeneic and allogeneic tumors. II. Characterization of effector cells

1975 • 844 citations

Anti-viral activity induced by culturing lymphocytes with tumor-derived or virus-transformed cells. Enhancement of human natural killer cell activity by interferon and antagonistic inhibition of susceptibility of target cells to lysis.

1978 • 744 citations

Augmentation of Mouse Natural Killer Cell Activity by Interferon and Interferon Inducers

1979 • 608 citations

Natural Cytotoxic Reactivity of Human Lymphocytes Against a Myeloid Cell Line: Characterization of Effector Cells

1977 • 493 citations

Evidence for a similar or common mechanism for natural killer cell activity and resistance to hemopoietic grafts

1977 • 467 citations

Immunologic functions of isolated human lymphocyte subpopulations. I. Quantitative isolation of human T and B cells and response to mitogens.

1974 • 296 citations

Cytotoxic cells induced during lymphocytic choriomeningitis virus infection of mice. I. Characterization of natural killer cell induction

1978 • 296 citations

Surface Antigenic Markers for Distinguishing T and B Lymphocytes in Mice

1971 • 295 citations

A Functional Comparison of Human Fc-Receptor-Bearing Lymphocytes Active in Natural Cytotoxicity and Antibody-Dependent Cellular Cytotoxicity

1977 • 292 citations

Anti-viral activity induced by culturing lymphocytes with tumor-derived or virus-transformed cells. Identification of the anti-viral activity as interferon and characterization of the human effector lymphocyte subpopulation.

1978 • 292 citations

Augmentation of natural cytotoxic reactivity of mouse lymphoid cells against syngeneic and allogeneic target cells

1977 • 288 citations

Spontaneous human lymphocyte‐mediated cytotoxicity againts tumour target cells. I. The effect of malignant disease

1976 • 258 citations

Genetic variation of in vitro cytolytic activity and in vivo rejection potential of non‐immunized semi‐syngeneic mice against a mouse lymphoma line

1975 • 230 citations

Induction of “natural killer” cells by BCG

1976 • 205 citations

Cell-mediate cytotoxicity in vitro of human lymphocytes against a tissue culture melanoma cell line (igr3).

1975 • 195 citations

Low Density of Thy 1 Antigen on Mouse Effector Cells Mediating Natural Cytotoxicity Against Tumor Cells

1978 • 195 citations

Cytotoxic lymphocytes from normal donors. A functional marker of human non-T lymphocytes.

1975 • 193 citations

Destruction of Human Lymphoid Tissue-Culture Cell Lines by Human Peripheral Lymphocytes in 51Cr-Release Cellular Cytotoxicity Assays2

1974 • 183 citations

Cytotoxic cells induced during lymphocytic choriomeningitis virus infection of mice. II. "Specificities" of the natural killer cells.

1979 • 182 citations

Cytolytic and cytostatic activity on tumor cells of circulating human monocytes

1979 • 177 citations

Killer cells: a functional comparison between natural, immune T-cell and antibody-dependent in vitro systems.

1976 • 174 citations

Natural cell‐mediated cytotoxicity in mice against non‐lymphoid tumor cells and some normal cells

1977 • 174 citations

Advances in Cancer Research

1975 • 174 citations

Cytotoxic Reactivity of Human Lymphocytes Cultured in Vitro

1977 • 169 citations

Immunologic Functions of Isolated Human Lymphocyte Subpopulations

1974 • 168 citations

Specificity of Natural Cytotoxic Reactivity of Normal Human Lymphocytes Against a Myeloid Leukemia Cell Line

1977 • 163 citations

HLA-Related Control of Spontaneous and Antibody-Dependent Cell-Mediated Cytotoxic Activity in Humans

1976 • 161 citations

Heterospecific cytotoxic cell activity induced during the first three days of acute lymphocytic choriomeningitis virus infection in mice

1977 • 155 citations

Rapid In Vivo Assay of Mouse Natural Killer Cell Activity<xref ref-type="fn" rid="FN2">2</xref>

1979 • 154 citations

Decline of natural non-selective cell-mediated cytotoxicity in patients with tumor progression

1977 • 154 citations

Cell-Mediated Cytotoxicity in Vitro of Human Lymphocytes against a Tissue Culture Melanoma Cell Line (IGR3)

1975 • 148 citations

Natural cell‐mediated cytotoxicity in rats. II. In vivo augmentation of NK‐cell activity

1978 • 147 citations

Natural Occurrence of Lymphocytes Showing Cytotoxic Activity to BALB/c Radiation-Induced Leukemia RL ♂ 1 Cells

1975 • 144 citations

Lymphocyte cytotoxicity reactions to leukemia‐associated antigens in identical twins

1972 • 143 citations

Natural Killer Cells may be the Only Cells in Normal Mouse Lymphoid Cell Populations Endowed with Cytolytic Ability for Antibody‐Coated Tumour Target Cells

1978 • 140 citations

Low affinity E-rosette formation by the human K cell.

1978 • 129 citations

Natural cell‐mediated cytotoxicity in rats. III. Effects of immunopharmacologic treatments on natural reactivity and on reactivity augmented by polyinosinic‐polycytidylic acid

1978 • 125 citations

Effect of Antibody to 9 Antigen on Cell-Mediated Immunity Induced in Syngeneic Mice by Murine Sarcoma Virus 2

1973 • 116 citations

Natural Cytotoxicity of Mouse Monocytes and Macrophages

1979 • 116 citations

Cytotoxity of non‐T versus T‐lymphocytes from melanoma patients and healthy donors on short‐ and long‐term cultured melanoma cells

1974 • 114 citations

Natural Cytotoxic Reactivity of Rat Lymphocytes Against Syngeneic Gross Virus-Induced Lymphoma2

1976 • 111 citations

Target—effector interaction in the natural killer cell system: Isolation of target structures

1979 • 110 citations

Natural Killing in Immunodeficient Patients

1978 • 108 citations

Target‐Effector Interaction in the Natural Killer Cell System

1978 • 107 citations

High frequency of T lineage lymphocytes in nude mouse spleen

1974 • 102 citations

The Nonselective Cytotoxic Cell (N Cell) 2

1976 • 99 citations

Decreased “natural killer” effect in tumor‐bearing mice and its relation to the immunity against oncorna virus‐determined cell surface antigens

1976 • 89 citations

Macrophage-mediated natrual cytotoxicity against various target cells in vitro. I. Macrophages from diverse anatomical sites and different strains of rats and mice

1978 • 89 citations

The Use of Fab Fragments of Anti-Human Immunoglobulin as Analytic Tools for Establishing the Involvement of Immunoglobulin in the Spontaneous Cytotoxicity to Cultured Tumor Cells by Lymphocytes from Patients with Bladder Carcinoma and from Healthy Donors

1977 • 88 citations

The effect of immunopharmacological agents on mouse natural cell-mediated cytotoxicity and on its augmentation by poly I:C

1979 • 82 citations

Characterization of natural killer (NK) cells and killer (K) cells in human blood: Discrimination between NK and K cell activities

1978 • 82 citations

Resistance ofH-2 heterozygous mice to parental tumors

1977 • 81 citations

Two Cytotoxic Cells in Peritoneal Cavity of Virus-Infected Mice: Antibody-Dependent Macrophages and Nonspecific Killer Cells

1977 • 80 citations

Functional Activities of Rosette Separated Human Peripheral Blood Leukocytes

1975 • 76 citations

Rosette Formation by the Human K Cell

1978 • 75 citations

Human natural cytotoxicity in the blood and lymphoid organs of healthy donors and patients with malignant disease

1978 • 73 citations

Natural cell‐mediated cytotoxicity in rats. I. Tissue and strain distribution, and demonstration of a membrane receptor for the Fc portion of IgG

1978 • 72 citations

Gross‐virus‐induced lymphoma in the rat. V. Natural cytotoxic cells are non‐t cells

1977 • 71 citations

Selective cellular natural killing against human leukaemic T cells and thymus

1977 • 70 citations

Expression of Human T-Lymphocyte Antigens by Natural Killer Cells2

1978 • 70 citations

Determination of Specificity in Natural Cell-Mediated Cytotoxicity by Natural Antibodies 2

1977 • 69 citations

Natural cytotoxicity to human leukemia mediated by mouse non‐t cells

1977 • 66 citations

Current trends in tumor immunology

1979 • 63 citations

Characterization of cytolytic effector cells in peripheral blood of healthy individuals and cancer patients. II. Cytotoxicity to allogeneic or autochthonous tumor cells in tissue culture.

1977 • 63 citations

Characterization of human lymphocyte subpopulations for cytotoxicity against tumor‐derived monolayer cultures

1977 • 55 citations

Characterization of the human natural killer (NK) cell in blood and lymphoid organs

1978 • 53 citations

51 Chromium-release assay for cell-mediated cytotoxicity of human leukemia and lymphoid tissue-culture cells.

1973 • 53 citations

Characterization of the Blastogenic and Cytotoxic Responses of Normal Mice to Ecotropic C-Type Viral gp71

1977 • 49 citations

Spontaneous human lymphocyte-mediated cytotoxicity against tumor target cells

1979 • 49 citations

Correlation Between Natural and Antibody-Dependent Cell-Mediated Cytotoxicity Against Tumor Targets in the Mouse. I. Distribution of the Reactivity

1979 • 49 citations

In vitro inhibition of lymphoproliferative responses to tumor associated antigens and of lymphoma cell proliferation by rat splenic macrophages

1977 • 47 citations

Role of interferon in augmentation of natural and antibody-dependent cell-mediated cytotoxicity.

1978 • 47 citations

Specificities in natural cell‐mediated cytotoxicity by the cross‐competition assay

1977 • 47 citations

Granulocytes as effectors in cell-mediated cytotoxicity of adherent target cells.

1975 • 44 citations

Characterization of Cytolytic Effector Cells in Peripheral Blood of Healthy Individuals and Cancer Patients

1977 • 41 citations

Cytotoxicity against the K562 erythroleukemia cell line by human natural killer (NK) cells which do not bear free Fc receptors for IgG

1979 • 40 citations

Production of an antiviral factor by murine spleen cells after treatment with Corynebacterium parvum

1977 • 40 citations

Spontaneous human lymphocyte‐mediated cytotoxicity against tumor target cells. II. Is the complement receptor necessarily present on the killer cells?

1977 • 39 citations

Evaluation of the Role of IgG Antibodies in Human Natural Cell-Mediated Cytotoxicity Against the Myeloid Cell Line K562

1979 • 38 citations

Abrogation of resistance to foreign bone marrow grafts by carrageenans. I. Studies with the anti-macrophage agent seakem carrageenan.

1977 • 38 citations

Antibody-Dependent Cellular Cytotoxicity to a Syngeneic Gross Virus-Induced Lymphoma 2

1974 • 37 citations

Correlation Between Natural and Antibody-Dependent Cell-Mediated Cytotoxicity Against Tumor Targets in the Mouse. II. Characterization of the Effector Cells

1979 • 36 citations

Standing Waves on the Moon

1969 • 33 citations

Radioresistant inhibition of lymphoma growth in congenitally athymic (nude) mice.

1977 • 32 citations

Cytotoxicity from cultured cells: Analysis of precursors involved in generation of human cells mediating natural and antibody-dependent cell-mediated cytotoxicity

1979 • 23 citations

Abrogation of Resistance to Foreign Bone Marrow Grafts by Carrageenans

1977 • 22 citations

Production of Functional T Cells after Treatment of Bone Marrow with Thymic Factor

1973 • 21 citations

Enrichment of in vitro and in vivo immunologic activity of purified fractions of calf thymic hormone.

1978 • 21 citations

Identification of the effector cells in human blood displaying spontaneous cytotoxicity to chicken erythrocytes

1977 • 18 citations

Natural killer cells in guinea pig spleen bear Fc receptors

1978 • 17 citations

Inhibition of Lymphoma Growth in the Spleen and Liver of Lethally Irradiated Mice

1978 • 16 citations

Growth Inhibition of Normal or Drug-Treated Lymphoma Cells in Lethally Irradiated Mice2

1978 • 16 citations

Interferonogenicity of antigens and "early" cytotoxicity of lymphocytes.

1974 • 10 citations

IN VITRO INDUCTION OF NATURAL KILLER (NK) AND KILLER (K) CELLS

1977 • 4 citations