Selective displacement of nuclear proteins by antitumor drugs having affinity for nucleic acids.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

The Reliability of Molecular Weight Determinations by Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis

1969 • 20,498 citations

Structural considerations in the interaction of DNA and acridines

1961 • 2,199 citations

Complex formation between ethidium bromide and nucleic acids

1965 • 1,485 citations

Identification of mammalian DNA topoisomerase I as an intracellular target of the anticancer drug camptothecin.

1988 • 843 citations

Studies of the binding of actinomycin and related compounds to DNA

1968 • 842 citations

Actinomycin and DNA transcription.

1985 • 535 citations

4. Intercalation chemistry

1982 • 358 citations

Accessibility of DNA in situ to various fluorochromes: Relationship to chromatin changes during erythroid differentiation of friend leukemia cells

1984 • 263 citations

Nuclear proteins

1976 • 196 citations

Correlations between intercalator-induced DNA strand breaks and sister chromatid exchanges, mutations, and cytotoxicity in Chinese hamster cells.

1985 • 174 citations

Experimental antitumor activity of aminoanthraquinones.

1979 • 131 citations

Relationship between the pharmacological activity of antitumor drugs Ametantrone and mitoxantrone (Novatrone) and their ability to condense nucleic acids.

1986 • 104 citations

Ethidium bromide as a probe of conformational heterogeneity of DNA in chromatin. The role of histone H₁

1976 • 85 citations

Condensation of nucleic acids by intercalating aromatic cations.

1984 • 67 citations

DNA intercalators induce specific release of HMG 14, HMG 17 and other DNA-binding proteins from chicken erythrocyte chromatin.

1985 • 53 citations

Relaxation of chromatin structure by ethidium bromide binding: determined by viscometry and histone dissociation studies

1976 • 30 citations

Relaxation of Chromatin Structure Induced by Ethidium Binding. Involvement of the Intercalation Process

1979 • 23 citations

Nuclease digestibility of chromatin is affected by nuclei isolation procedures

1983 • 21 citations

Modifications of the chromatin arrangement induced by ethidium bromide in isolated nuclei, analyzed by electron microscopy and flow cytometry

1987 • 16 citations

HMG proteins released from the chromatin following incubation of mammalian nuclei with ethidium bromide

1989 • 10 citations

Interactions of antitumor drug ditercalinium with nucleic acids in solutions and in situ

1988 • 5 citations