Dietary fat clearance in normal subjects is regulated by genetic variation in apolipoprotein E.

Dextran sulfate-Mg2+ precipitation procedure for quantitation of high-density-lipoprotein cholesterol.

1982 • 2,206 citations

HDL cholesterol and other lipids in coronary heart disease. The cooperative lipoprotein phenotyping study.

1977 • 1,517 citations

Lipoprotein receptors and cholesterol homeostasis

1983 • 755 citations

Human apolipoprotein E. The complete amino acid sequence.

1982 • 731 citations

Role of the apolipoprotein E polymorphism in determining normal plasma lipid and lipoprotein variation.

1985 • 714 citations

Abnormal lipoprotein receptor-binding activity of the human E apoprotein due to cysteine-arginine interchange at a single site.

1982 • 674 citations

Polymorphism of apolipoprotein E and occurrence of dysbetalipoproteinaemia in man

1977 • 654 citations

Human very low density lipoprotein apolipoprotein E isoprotein polymorphism is explained by genetic variation and posttranslational modification

1981 • 568 citations

Selective Measurement of Two Lipase Activities in Postheparin Plasma from Normal Subjects and Patients with Hyperlipoproteinemia

1974 • 444 citations

Rapid hepatic clearance of the canine lipoproteins containing only the E apoprotein by a high affinity receptor. Identity with the chylomicron remnant transport process.

1980 • 428 citations

Proposed nomenclature of apoE isoproteins, apoE genotypes, and phenotypes

1982 • 420 citations

Apolipoprotein E polymorphism in the Finnish population: gene frequencies and relation to lipoprotein concentrations.

1987 • 410 citations

Polymorphism of apolipoprotein E

1979 • 405 citations

Lipoprotein binding to canine hepatic membranes. Metabolically distinct apo-E and apo-B,E receptors.

1981 • 391 citations

Two independent lipoprotein receptors on hepatic membranes of dog, swine, and man. Apo-B,E and apo-E receptors.

1981 • 378 citations

Regulation of the hepatic uptake of triglyceride-rich lipoproteins in the rat. Opposing effects of homologous apolipoprotein E and individual C apoproteins.

1980 • 372 citations

Effect of apoproteins on hepatic uptake of triglyceride emulsions in the rat.

1980 • 359 citations

Apolipoprotein E polymorphism and coronary artery disease.

1983 • 352 citations

Heterogeneity of human plasma very low density lipoproteins. Separation of species differing in protein components

1973 • 349 citations

Abnormal in vivo metabolism of apolipoprotein E4 in humans.

1986 • 343 citations

Human apolipoprotein E isoprotein subclasses are genetically determined.

1981 • 341 citations

Prevalence of coronary heart disease in the framingham offspring study: Role of lipoprotein cholesterols

1980 • 321 citations

Particulate Fat in Lymph and Blood

1962 • 292 citations

The receptor-binding domain of human apolipoprotein E. Binding of apolipoprotein E fragments.

1983 • 276 citations

Different patterns of postprandial lipoprotein metabolism in normal, type IIa, type III, and type IV hyperlipoproteinemic individuals. Effects of treatment with cholestyramine and gemfibrozil.

1987 • 263 citations

Polymorphism at the Apoprotein‐E locus in relation to risk of coronary disease

1984 • 254 citations

Apolipoprotein E phenotypes and hyperlipidemia

1984 • 246 citations

Human Intestinal Lipoproteins

1979 • 245 citations

The receptor-binding domain of human apolipoprotein E. Monoclonal antibody inhibition of binding.

1983 • 226 citations

Composition of proteins of mesenteric lymph chylomicrons in the rat and alterations produced upon exposure of chylomicrons to blood serum and serum proteins.

1978 • 223 citations

Chylomicron clearance in normal and hyperlipidemic man

1976 • 218 citations

Hepatic retinol metabolism. Distribution of retinoids, enzymes, and binding proteins in isolated rat liver cells.

1985 • 211 citations

Apoprotein (E–A-II) complex of human plasma lipoproteins. I. Characterization of this mixed disulfide and its identification in a high density lipoprotein subfraction.

1978 • 211 citations

Radioimmunoassay of human arginine-rich apolipoprotein, apoprotein E. Concentration in blood plasma and lipoproteins as affected by apoprotein E-3 deficiency.

1980 • 188 citations

Radioimmunoassay studies of human apolipoprotein E.

1980 • 179 citations

Normalization of receptor binding of apolipoprotein E2. Evidence for modulation of the binding site conformation.

1984 • 178 citations

Delayed clearance of chylomicron remnants following vitamin-A-containing oral fat loads in broad-β disease (type III hyperlipoproteinemia)

1976 • 172 citations

Structural and metabolic heterogeneity of beta-very low density lipoproteins from cholesterol-fed dogs and from humans with type III hyperlipoproteinemia.

1982 • 157 citations

Apolipoprotein E polymorphism and hyperlipidemia.

1984 • 137 citations

Dynamics of apolipoprotein E metabolism in humans

1982 • 135 citations

Plasma clearance of chylomicrons labeled with retinyl palmitate in healthy human subjects.

1984 • 132 citations

Kinetics of chylomicron remnant clearance in normal and in hyperlipoproteinemic subjects.

1987 • 124 citations

Simultaneous determination of retinol and retinyl esters in serum or plasma by reversed-phase high-performance liquid chromatography.

1978 • 106 citations

Type III hyperlipoproteinemia: recent insights into the genetic defect of familial dysbetalipoproteinemia.

1984 • 93 citations

Genetic variation in human apolipoprotein E

1982 • 90 citations

Membrane Changes Associated with Platelet Activation

1980 • 84 citations

Effects of apoprotein E polymorphism on serum lipoprotein concentration.

1985 • 82 citations

Contraceptive steroids increase hepatic uptake of chylomicron remnants in healthy young women.

1988 • 70 citations

Plasma lipoprotein retinoids after vitamin A feeding in normal man: Minimal appearance of retinyl esters among low-density lipoproteins

1983 • 67 citations

Plasma decay of chylomicron remnants is not affected by heparin-stimulated plasma lipolytic activity in normal fasting man.

1985 • 52 citations

Postchallenge plasma lipoprotein retinoids: Chylomicron remnants in endogenous hypertriglyceridemia

1985 • 51 citations

Characterization of very low density lipoproteins and intermediate density lipoproteins of normo- and hyperlipidemic apolipoprotein E-2 homozygotes.

1985 • 22 citations