Sphingolipid Biosynthesis de Novo by Rat Hepatocytes in Culture.

THE DISTRIBUTION AND CHEMICAL COMPOSITION OF ULTRACENTRIFUGALLY SEPARATED LIPOPROTEINS IN HUMAN SERUM

1955 • 8,846 citations

Inhibition of sphingolipid biosynthesis by fumonisins. Implications for diseases associated with Fusarium moniliforme

1991 • 1,094 citations

Bifunctional role of glycosphingolipids. Modulators for transmembrane signaling and mediators for cellular interactions.

1990 • 889 citations

Identification of sphingomyelin turnover as an effector mechanism for the action of tumor necrosis factor alpha and gamma-interferon. Specific role in cell differentiation.

1991 • 621 citations

The active synthesis of phosphatidylcholine is required for very low density lipoprotein secretion from rat hepatocytes.

1988 • 601 citations

An update of the enzymology and regulation of sphingomyelin metabolism

1990 • 460 citations

Biochemistry of Lipids, Lipoproteins and Membranes

1992 • 438 citations

Tumor Necrosis Factor-α Activates the Sphingomyelin Signal Transduction Pathway in a Cell-Free System

1992 • 428 citations

Ceramide stimulates a cytosolic protein phosphatase.

1992 • 406 citations

Sphingomyelins in bilayers and biological membranes

1980 • 367 citations

Fumonisin B1 inhibits sphingosine (sphinganine) N-acyltransferase and de novo sphingolipid biosynthesis in cultured neurons in situ.

1993 • 363 citations

[3] Comparative analysis of mammalian plasma lipoproteins

1986 • 318 citations

Quantitation of free sphingosine in liver by high-performance liquid chromatography

1988 • 315 citations

Ganglioside metabolism. Enzymology, Topology, and regulation.

1993 • 310 citations

Sphingomyelin and derivatives as cellular signals

1991 • 275 citations

Cell regulation by sphingosine and more complex sphingolipids

1991 • 242 citations

Phosphatidylcholine metabolism: masochistic enzymology, metabolic regulation, and lipoprotein assembly

1990 • 186 citations

The Enzymatic Formation of Sphingomyelin from Ceramide and Lecithin in Mouse Liver

1974 • 179 citations

Sphingomyelins in bilayers and biological membranes

1980 • 172 citations

Sterol partitioning among intracellular membranes. Testing a model for cellular sterol distribution.

1983 • 163 citations

Interaction of Cholesterol with Sphingomyelin in Monolayers and Vesicles

1994 • 159 citations

Characterization of serine palmitoyltransferase activity in Chinese hamster ovary cells

1983 • 151 citations

Biosynthesis of long-chain (sphingoid) bases from serine by LM cells. Evidence for introduction of the 4-trans-double bond after de novo biosynthesis of N-acylsphinganine(s).

1986 • 145 citations

Biosynthesis of sphingolipids: Dihydroceramide and not sphinganine is desaturated by cultured cells

1992 • 144 citations

Reduction in VLDL, but not HDL, in plasma of rats deficient in choline

1990 • 140 citations

Correlative relationship of cholesterol and sphingomyelin in cell membranes

1970 • 125 citations

Factors contributing to the distribution of cholesterol among phospholipid vesicles.

1986 • 122 citations

Movement of cholesterol between vesicles prepared with different phospholipids or sizes.

1985 • 119 citations

The affinity of cholesterol for phosphatidylcholine and sphingomyelin

1979 • 100 citations

Kinetics of long-chain (sphingoid) base biosynthesis in intact LM cells: effects of varying the extracellular concentrations of serine and fatty acid precursors of this pathway

1988 • 97 citations

Modulation of sphingolipid biosynthesis in primary cultured neurons by long chain bases.

1990 • 96 citations

[51] Enzymes of ceramide biosynthesis

1992 • 81 citations

Neutral sphingomyelinase action stimulates signal transduction of tumor necrosis factor-alpha in the synthesis of cholesteryl esters in human fibroblasts.

1994 • 80 citations

Sphingomyelin suppresses the binding and utilization of low density lipoproteins by skin fibroblasts.

1980 • 80 citations

STRUCTURAL STUDIES OF BIOLOGICAL MEMBRANES: THE STRUCTURE OF MYELIN^*

1965 • 76 citations

Association and assembly of triglyceride and phospholipid with glycosylated and unglycosylated apoproteins of very low density lipoprotein in the intact liver cell.

1982 • 66 citations

Sphingomyelin and ceramide-phosphoethanolamine synthesis by microsomes and plasma membranes from rat liver and brain.

1987 • 65 citations

Sphingomyelin transport to the cell surface occurs independently of protein secretion in rat hepatocytes.

1993 • 53 citations

Localization of shed human tumor gangliosides: association with serum lipoproteins.

1992 • 51 citations

Effects of sphingomyelin degradation on cholesterol mobilization and efflux to high-density lipoproteins in cultured fibroblasts

1990 • 41 citations

Regulation of sphingomyelin long chain base synthesis in human fibroblasts in culture. Role of lipoproteins and the low density lipoprotein receptor.

1982 • 39 citations

Stimulation of sphingomyelin biosynthesis by brefeldin A and sphingomyelin breakdown by okadaic acid treatment of rat hepatocytes.

1992 • 38 citations

Cholesterol and sphingomyelin syntheses are regulated independently in cultured human intestinal cells, CaCo-2: role of membrane cholesterol and sphingomyelin content.

1993 • 38 citations

Effect of positively charged sphingomyelin liposomes on cholesterol metabolism of cells in culture

1983 • 36 citations

Regulation of synthesis of lactosylceramide and long chain bases in normal and familial hypercholesterolemic cultured proximal tubular cells.

1986 • 32 citations

Sphingolipid Biosynthesis by Rat Liver Cells: Effects of Serine, Fatty Acids and Lipoproteins

1989 • 32 citations

Release of ceramide after membrane sphingomyelin hydrolysis decreases the basolateral secretion of triacylglycerol and apolipoprotein B in cultured human intestinal cells.

1993 • 27 citations

Metabolism of neutral glycosphingolipids in plasma of a normal human and a patient with Fabry's disease.

1975 • 24 citations

Sphingomyelin liposomes with defined fatty acids: metabolism and effects on reverse cholesterol transport

1988 • 21 citations

Metabolism of phosphatidyl choline, phosphatidyl ethanolamine and sphingomyelin in regenerating rat liver

1971 • 20 citations

Age- and Hormone-Dependent Ganglioside Patterns of Rat Hepatocytes in Primary Culture

1985 • 18 citations

Use of cytochrome P-450scc to measure cholesterol-lipid interactions

1986 • 15 citations

Occurrence and Biosynthesis of Ceramide Phosphorylethanolamine in Chicken and Rat Liver

1972 • 15 citations

Impairment of exogenous sphingomyelin degradation in cultured fibroblasts from familial hypercholesterolemia

1984 • 9 citations