Glutathione peroxidase inhibits cell death and glial activation following experimental stroke

Pathobiology of ischaemic stroke: an integrated view

1999 • 3,776 citations

Ischemic Cell Death in Brain Neurons

1999 • 2,974 citations

Cytochemical Identification of Monocytes and Granulocytes

1971 • 2,735 citations

Reactive Oxygen Radicals in Signaling and Damage in the Ischemic Brain

2001 • 1,558 citations

Importance of SE-glutathione peroxidase, catalase, and CU/ZN-SOD for cell survival against oxidative stress

1994 • 1,178 citations

Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells.

1993 • 1,079 citations

Brain ischemia and reperfusion: molecular mechanisms of neuronal injury

2000 • 791 citations

Inflammation and glial responses in ischemic brain lesions

1998 • 788 citations

Oxidative Stress in Brain Ischemia

1999 • 681 citations

Isolation and direct characterization of resident microglial cells from the normal and inflamed central nervous system.

1991 • 675 citations

Polymorphonuclear leukocytes and monocytes/macrophages in the pathogenesis of cerebral ischemia and stroke.

1992 • 617 citations

Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing CuZn superoxide dismutase.

1991 • 591 citations

Human copper-zinc superoxide dismutase transgenic mice are highly resistant to reperfusion injury after focal cerebral ischemia.

1994 • 571 citations

Reduction of CuZn-Superoxide Dismutase Activity Exacerbates Neuronal Cell Injury and Edema Formation after Transient Focal Cerebral Ischemia

1997 • 436 citations

Polymorphonuclear leukocyte infiltration into cerebral focal ischemic tissue: Myeloperoxidase activity assay and histologic verification

1991 • 382 citations

Oxidant stress regulation of IL-8 and ICAM-1 gene expression: differential activation and binding of the transcription factors AP-1 and NF-kappaB (Review).

1999 • 318 citations

Ultrastructural and light microscopic evidence of apoptosis after middle cerebral artery occlusion in the rat.

1995 • 258 citations

Notch1 inhibits neurite outgrowth in postmitotic primary neurons

1999 • 215 citations

Leukotriene B4

1998 • 208 citations

Ebselen in Acute Middle Cerebral Artery Occlusion: A Placebo-Controlled, Double-Blind Clinical Trial

1999 • 205 citations

Overexpression of human glutathione peroxidase protects transgenic mice against focal cerebral ischemia/reperfusion damage

1998 • 179 citations

Global Cerebral Ischemia in the Rat: Online Monitoring of Oxygen Free Radical Production Using Chemiluminescence in vivo

1995 • 158 citations

The Catalytic Outcomes of the Constitutive and the Mitogen Inducible Isoforms of Prostaglandin H2 Synthase Are Markedly Affected by Glutathione and Glutathione Peroxidase(s)

1995 • 119 citations

Transgenic Mice and Knockout Mutants in the Study of Oxidative Stress in Brain Injury

1995 • 106 citations

Selective vulnerability of cultured cortical glia to injury by extracellular acidosis

1990 • 100 citations

Thermosensitive phenotype of transgenic mice overproducing human glutathione peroxidases.

1995 • 69 citations

An in vitro model for analysis of oxidative death in primary mouse astrocytes

1998 • 66 citations

Inflammatory Response and Glutathione Peroxidase in a Model of Stroke

2002 • 62 citations

Effect of overexpression of human Cu,Zn superoxide dismutase in transgenic mice on macrophage functions.

1996 • 61 citations

Enhanced neuronal protection from oxidative stress by coculture with glutamic acid decarboxylase‐expressing astrocytes

2001 • 40 citations

NF-?B activation by N-CAM and cytokines in astrocytes is regulated by multiple protein kinases and redox modulation

2001 • 34 citations

Neuroprotective effects of a new glutathione peroxidase mimetic on neurons of the chick embryo's retina

2000 • 27 citations