A low number of tumor-infiltrating FOXP3-positive cells during primary systemic chemotherapy correlates with favorable anti-tumor response in patients with breast cancer

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

2003 • 7,470 citations

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

2004 • 4,872 citations

CD4+CD25+ suppressor T cells: more questions than answers

2002 • 2,202 citations

Regulatory T cells in transplantation tolerance

2003 • 1,323 citations

Metronomic cyclophosphamide regimen selectively depletes CD4+CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patients

2006 • 1,180 citations

Ex Vivo Isolation and Characterization of Cd4+Cd25+ T Cells with Regulatory Properties from Human Blood

2001 • 1,168 citations

Quantification of Regulatory T Cells Enables the Identification of High-Risk Breast Cancer Patients and Those at Risk of Late Relapse

2006 • 1,118 citations

Human Cd25+Cd4+ T Regulatory Cells Suppress Naive and Memory T Cell Proliferation and Can Be Expanded in Vitro without Loss of Function

2001 • 1,008 citations

Prevalence of FOXP3+ Regulatory T Cells Increases During the Progression of Pancreatic Ductal Adenocarcinoma and Its Premalignant Lesions

2006 • 746 citations

Cyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cells.

1982 • 640 citations

Human CD4+CD25+ cells: a naturally occurring population of regulatory T cells

2001 • 615 citations

Regulatory T cells under scrutiny

2003 • 427 citations

Correlation of high numbers of intratumoral FOXP3+ regulatory T cells with improved survival in germinal center-like diffuse large B-cell lymphoma, follicular lymphoma and classical Hodgkin's lymphoma

2008 • 395 citations

Antigen-induced regulatory T cells in autoimmunity

2003 • 317 citations

Pathologic Complete Response to Neoadjuvant Chemotherapy of Breast Carcinoma Is Associated with the Disappearance of Tumor-Infiltrating Foxp3+ Regulatory T Cells

2008 • 294 citations

A Combination of Chemoimmunotherapies Can Efficiently Break Self-Tolerance and Induce Antitumor Immunity in a Tolerogenic Murine Tumor Model

2007 • 201 citations

Immunosuppressive regulatory T cells are associated with aggressive breast cancer phenotypes: a potential therapeutic target

2008 • 132 citations

In situ analysis of FOXP3+ regulatory T cells in human colorectal cancer

2006 • 122 citations

Localisation pattern of Foxp3+ regulatory T cells is associated with clinical behaviour in gastric cancer

2007 • 121 citations

Intratumoral FOXP3 expression in infiltrating breast carcinoma: Its association with clinicopathologic parameters and angiogenesis.

2007 • 119 citations

Histopathological criteria for assessment of therapeutic response in breast cancer (2007 version)

2007 • 100 citations

Possible involvement of regulatory T cells in tumor onset and progression in primary breast cancer

2008 • 94 citations

Prognostic value of tumor-infiltrating FOXP3+ regulatory T cells in patients with hepatocellular carcinoma

2007 • 89 citations

The impact of regulatory T cells on carcinogen-induced sarcogenesis

2007 • 68 citations

Evaluation of tumour-infiltrating CD4+CD25+FOXP3+ regulatory T cells in human cutaneous benign and atypical naevi, melanomas and melanoma metastases

2007 • 59 citations

Cyclophosphamide and abrogation of tumor-induced suppressor T cell activity

1990 • 59 citations

Long-term prognostic and predictive factors in 107 stage II/III breast cancer patients treated with anthracycline-based neoadjuvant chemotherapy

1997 • 49 citations