Pathologic Complete Response to Neoadjuvant Chemotherapy of Breast Carcinoma Is Associated with the Disappearance of Tumor-Infiltrating Foxp3+ Regulatory T Cells
Data up to Jan 2025
Total Citations Per Year
Abstract
References (33)
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
2003 • 7,470 citations
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
2004 • 4,872 citations
Intratumoral T Cells, Recurrence, and Survival in Epithelial Ovarian Cancer
2003 • 3,194 citations
Toll-like receptor 4–dependent contribution of the immune system to anticancer chemotherapy and radiotherapy
2007 • 2,814 citations
Calreticulin exposure dictates the immunogenicity of cancer cell death
2006 • 2,789 citations
Intraepithelial CD8+tumor-infiltrating lymphocytes and a high CD8+/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer
2005 • 2,226 citations
Effector Memory T Cells, Early Metastasis, and Survival in Colorectal Cancer
2005 • 1,985 citations
Foxp3+CD25+CD4+ natural regulatory T cells in dominant self‐tolerance and autoimmune disease
2006 • 1,535 citations
Prevalence of Regulatory T Cells Is Increased in Peripheral Blood and Tumor Microenvironment of Patients with Pancreas or Breast Adenocarcinoma
2002 • 1,454 citations
Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death
2005 • 1,330 citations
Clinical Course of Breast Cancer Patients With Complete Pathologic Primary Tumor and Axillary Lymph Node Response to Doxorubicin-Based Neoadjuvant Chemotherapy
1999 • 1,315 citations
Metronomic cyclophosphamide regimen selectively depletes CD4+CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patients
2006 • 1,180 citations
CD8+ T cells infiltrated within cancer cell nests as a prognostic factor in human colorectal cancer.
1998 • 1,175 citations
Regulatory CD4(+)CD25(+) T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer.
2001 • 1,126 citations
Quantification of Regulatory T Cells Enables the Identification of High-Risk Breast Cancer Patients and Those at Risk of Late Relapse
2006 • 1,118 citations
CD4+CD25+ regulatory T cells inhibit natural killer cell functions in a transforming growth factor–β–dependent manner
2005 • 889 citations
Immunotherapy and chemotherapy — a practical partnership
2005 • 639 citations
Proliferative activity of intratumoral CD8(+) T-lymphocytes as a prognostic factor in human renal cell carcinoma: clinicopathologic demonstration of antitumor immunity.
2001 • 625 citations
Increased Populations of Regulatory T Cells in Peripheral Blood of Patients with Hepatocellular Carcinoma
2005 • 618 citations
Trastuzumab-based treatment of HER2-positive breast cancer: an antibody-dependent cellular cytotoxicity mechanism?
2006 • 518 citations
Prognostic significance of activated CD8(+) T cell infiltrations within esophageal carcinomas.
2001 • 496 citations
Increased populations of regulatory T cells in peripheral blood and tumor-infiltrating lymphocytes in patients with gastric and esophageal cancers.
2003 • 487 citations
Cyclophosphamide, doxorubicin, and paclitaxel enhance the antitumor immune response of granulocyte/macrophage-colony stimulating factor-secreting whole-cell vaccines in HER-2/neu tolerized mice.
2001 • 454 citations
Pathologic response to induction chemotherapy in locally advanced carcinoma of the breast: a determinant of outcome.
1995 • 422 citations
Inflammatory breast cancer: PET/CT, MRI, mammography, and sonography findings
2007 • 314 citations
Inflammatory breast cancer. Pilot study of intensive induction chemotherapy (FEC-HD) results in a high histologic response rate.
1993 • 271 citations
Histological grade, perineural infiltration, tumour-infiltrating lymphocytes and apoptosis as determinants of long-term prognosis in prostatic adenocarcinoma
1994 • 257 citations
Inflammatory Breast Cancer
1993 • 232 citations
Structural Representations of Tumor-Host Relationships in Mammary Carcinoma: Biologic and Prognostic Significance
1956 • 147 citations
T-Cell Activation Marker Expression on Tumor-Infiltrating Lymphocytes As Prognostic Factor in Cutaneous Malignant Melanoma
2004 • 145 citations
CD4+CD25+ Regulatory T-Cell Frequency in HER-2/neu (HER)-Positive and HER-Negative Advanced-Stage Breast Cancer Patients
2007 • 104 citations
TIA-1: Structural and Functional Studies on a New Class of Cytolytic Effector Molecule
1995 • 81 citations
A Better Way for a Cancer Cell to Die
2006 • 63 citations