Altered expression of complement receptors as a pathogenetic factor in systemic lupus erythematosus

Human complement C3b inactivator: isolation, characterization, and demonstration of an absolute requirement for the serum protein beta1H for cleavage of C3b and C4b in solution.

1977 • 685 citations

Identification of the membrane glycoprotein that is the C3b receptor of the human erythrocyte, polymorphonuclear leukocyte, B lymphocyte, and monocyte

1980 • 645 citations

Anti-Mac-1 selectively inhibits the mouse and human type three complement receptor.

1982 • 615 citations

The role of membrane receptors for C3b and C3d in phagocytosis.

1977 • 536 citations

Defective Reticuloendothelial System Fc-Receptor Function in Systemic Lupus Erythematosus

1979 • 535 citations

Primate erythrocyte-immune complex-clearing mechanism.

1983 • 495 citations

Family study of the major histocompatibility complex in patients with systemic lupus erythematosus: importance of null alleles of C4A and C4B in determining disease susceptibility.

1983 • 456 citations

Tumor-promoting phorbol esters stimulate C3b and C3b' receptor-mediated phagocytosis in cultured human monocytes.

1982 • 444 citations

Regulation of the amplification C3 convertase of human complement by an inhibitory protein isolated from human erythrocyte membrane

1979 • 444 citations

Reversal of Impaired Splenic Function in Patients with Nephritis or Vasculitis (or Both) by Plasma Exchange

1979 • 356 citations

Complement receptor (CR1) deficiency in erythrocytes from patients with systemic lupus erythematosus.

1982 • 347 citations

Unique role of the complement receptor CR1 in the degradation of C3b associated with immune complexes.

1982 • 335 citations

Mode of Inheritance of Decreased C3b Receptors on Erythrocytes of Patients with Systemic Lupus Erythematosus

1982 • 334 citations

Inhibition of phagocytosis of complement C3- or immunoglobulin G-coated particles and of C3bi binding by monoclonal antibodies to a monocyte-granulocyte membrane glycoprotein (Mol).

1983 • 303 citations

Generation of three different fragments of bound C3 with purified factor I or serum. I. Requirements for factor H vs CR1 cofactor activity.

1982 • 296 citations

Complement dependent immune phagocytosis

1968 • 295 citations

TWO DIFFERENT COMPLEMENT RECEPTORS ON HUMAN LYMPHOCYTES

1973 • 285 citations

Plasma fibronectin enhances phagocytosis of opsonized particles by human peripheral blood monocytes.

1983 • 278 citations

Fibronectin and serum amyloid P component stimulate C3b- and C3bi-mediated phagocytosis in cultured human monocytes.

1983 • 273 citations

Complement receptor is an inhibitor of the complement cascade.

1981 • 267 citations

Expression of C3d receptors during human B cell differentiation: immunofluorescence analysis with the HB-5 monoclonal antibody.

1984 • 263 citations

Identification of a 145,000 Mr membrane protein as the C3d receptor (CR2) of human B lymphocytes.

1984 • 257 citations

Identification of the membrane receptor for the complement fragment C3d by means of a monoclonal antibody.

1983 • 241 citations

Inherited deficiency of the second component of complement. Rheumatic disease associations.

1976 • 238 citations

The molecular basis for the difference in immune hemolysis activity of the Chido and Rodgers isotypes of human complement component C4.

1984 • 237 citations

DEFECTIVE IMMUNE-ADHERENCE (C3b) RECEPTOR ON ERYTHROCYTES FROM PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS

1981 • 226 citations

Breakdown of C3 after complement activation. Identification of a new fragment C3g, using monoclonal antibodies.

1982 • 202 citations

Immunohistochemical study of the human glomerular C3b receptor in normal kidney and in seventy-five cases of renal diseases: loss of C3b receptor antigen in focal hyalinosis and in proliferative nephritis of systemic lupus erythematosus.

1982 • 189 citations

A receptor for the third component of complement in the human renal glomerulus

1975 • 185 citations

Surface Markers on Human B and T Lymphocytes

1976 • 181 citations

Development of functional complement receptors during in vitro maturation of human monocytes into macrophages.

1980 • 154 citations

Generation of three different fragments of bound C3 with purified factor I or serum. II. Location of binding sites in the C3 Fragments for Factors B and H, complement receptors , and bovine conglutinin

1983 • 151 citations

Polymorphism of human erythrocyte C3b/C4b receptor.

1983 • 145 citations

Inhibition of immune precipitation by complement.

1980 • 141 citations

Genetic regulation of a structural polymorphism of human C3b receptor.

1983 • 135 citations

Human Lymphocytes Bear Membrane Receptors for C3b and C3d

1973 • 118 citations

COMPLEMENT, THE IMMUNE-COMPLEX LATTICE, AND THE PATHOPHYSIOLOGY OF COMPLEMENT-DEFICIENCY SYNDROMES

1983 • 115 citations

Membrane distribution and adsorptive endocytosis by C3b receptors on human polymorphonuclear leukocytes.

1981 • 112 citations

Characterization of human T lymphocytes that express the C3b receptor.

1983 • 109 citations

Augmentation of macrophage complement receptor function in vitro. I. Characterization of the cellular interactions required for the generation of a T-lymphocyte product that enhances macrophage complement receptor function.

1979 • 106 citations

Receptor Specific Clearance by the Reticuloendothelial System in Chronic Liver Diseases

1978 • 105 citations

Polymorphism of the human C3b/C4b receptor. Identification of a third allele and analysis of receptor phenotypes in families and patients with systemic lupus erythematosus.

1984 • 104 citations

Requirements for the solubilization of immune aggregates by complement. The role of the classical pathway.

1978 • 103 citations

Binding reaction between the third human complement protein and small molecules

1981 • 102 citations

Suppression of T lymphocyte functions by human C3 fragments. I. Inhibition of human T cell proliferative responses by a kallikrein cleavage fragment of human iC3b.

1983 • 93 citations

Immunoglobulin production by human peripheral lymphocytes induced by anti-C3 receptor antibodies.

1984 • 93 citations

Inherited Complement Deficiency States and SLE

1982 • 86 citations

Theβ-Cys-γ-Glu thiolester bond in human C3, C4, andα 2-macroglobulin

1983 • 85 citations

Defective Fc Receptor-Mediated Function of the Mononuclear Phagocyte System in Lupus Nephritis

1982 • 84 citations

Expression of C3b receptors on human be cells and myelomonocytic cells but not natural killer cells.

1983 • 83 citations

Regulation of immune response by components of the complement cascade and their activated fragments

1983 • 78 citations

Decreased Complement Mediated Binding of Antibody/³H‐dsDNA Immune Complexes to the Red Blood Cells of Patients with Systemic Lupus Erythematosus, Rheumatoid Arthritis, and Hematologic Malignancies

1983 • 75 citations

Low C3B receptor reactivity on erythrocytes from patients with systemic lupus erythematosus detected by immune adherence hemagglutination and radioimmunoassays with monoclonal antibody

1984 • 63 citations

The β-Cys-γ-Glu Thiolester Bond in Human C3, C4, and α 2-Macroglobulin

1985 • 61 citations

Endocytosis of the C3b receptor of complement within coated pits in human polymorphonuclear leukocytes and monocytes.

1983 • 60 citations

Monoclonal antibodies to human complement receptor (CR1) detect defects in glomerular diseases

1983 • 55 citations

The LFA-1, Mac-1 glycoprotein family and its deficiency in an inherited disease.

1985 • 46 citations

Hereditary C2 Deficiency: Diagnosis and HLA Gene Complex Associations

1976 • 46 citations

The third component of complement inhibits human lymphocyte blastogenesis.

1981 • 45 citations

Selective activation of antigen-specific human B cells in recently immunized individuals by nonspecific factors in the absence of antigen.

1983 • 43 citations

Modulation of human lymphocyte function by C3a and C3a(70-77).

1982 • 35 citations

Specificity of C3 receptors that mediate phagocytosis by rat peritoneal mast cells.

1981 • 31 citations

Studies on the kinetics of binding of complement‐fixing dsdna/anti‐dsdna immune complexes to the red blood cells of normal individuals and patients with systemic lupus erythematosus

1984 • 28 citations

Molecular genetics of the major histocompatibility linked complement genes

1983 • 21 citations

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