Behavioral effects of d-cycloserine in rats: The role of anxiety level

Validation of open : closed arm entries in an elevated plus-maze as a measure of anxiety in the rat

1985 • 5,596 citations

Depression: a new animal model sensitive to antidepressant treatments

1977 • 4,272 citations

Molecular cloning and characterization of the rat NMDA receptor

1991 • 1,780 citations

The glycine site of the NMDA receptor — five years on

1993 • 440 citations

Rapid Communication: Adrenalectomy Attenuates Stress‐Induced Elevations in Extracellular Glutamate Concentrations in the Hippocampus

1993 • 345 citations

d-Cycloserine: A ligand for the coupled glycine receptor has partial agonist characteristics

1989 • 302 citations

Antidepressant activity of non-competitive and competitive NMDA receptor antagonists in a chronic mild stress model of depression

1994 • 270 citations

Alterations in the N-methyl-d-asparatate (NMDA) receptor complex in the frontal cortex of suicide victims

1995 • 263 citations

D-cycloserine, a positive modulator of the N-methyl-D-aspartate receptor, enhances performance of learning tasks in rats

1989 • 253 citations

High versus low reactivity to a novel environment: behavioural, pharmacological and neurochemical assessments

1999 • 243 citations

Temporal dynamics of glutamate efflux in the prefrontal cortex and in the hippocampus following repeated stress: effects of pretreatment with saline or diazepam

1997 • 235 citations

Multiple sites for the regulation of the N-methyl-D-aspartate receptor.

1988 • 208 citations

Individual response profiles of male Wistar rats in animal models for anxiety and depression

2002 • 186 citations

Anxiety and depression: a common neurobiological substrate?

1988 • 174 citations

d-Cycloserine acts as a partial agonist at the glycine modulatory site of the NMDA receptor expressed inXenopus oocytes

1990 • 168 citations

Diazepam changes risk assessment in an anxiety/defense test battery

1990 • 161 citations

Influence of various acute stressors on the activity of adult male rats in a holeboard and in the forced swim test

1991 • 110 citations

Characterization df a [³H]Glycine Recognition Site as a Modulatory Site of the N‐Methyl‐D‐Aspartate Receptor Complex

1989 • 106 citations

Actions of ?-cycloserine at the ? glycine receptor site in vivo

1991 • 105 citations

Adaptation of the NMDA receptor in rat cortex following chronic electroconvulsive shock or imipramine

1993 • 93 citations

Effects of NMDA Modulation in Scopolamine Dementiaa

1991 • 87 citations

MK-801 produces a reduction in anxiety-related antipredator defensiveness in male and female rats and a gender-dependent increase in locomotor behavior

1992 • 85 citations

Anxiolytic-like effects of glycine receptor ligands in the rat potentiated startle test

1993 • 79 citations

Relationship between anxiety and serotonin in the ventral striatum

1998 • 72 citations

Anxiolytic activity of glycine-B antagonists and partial agonists—No relation to intrinsic activity in the patch clamp

1997 • 71 citations

Anticonvulsant effects of the glycine/NMDA receptor ligands <scp>d</scp>‐cycloserine and <scp>d</scp>‐serine but not R‐(+)‐HA‐966 in amygdala‐kindled rats

1994 • 67 citations

d-Cycloserine, a putative cognitive enhancer, facilitates activation of the N-methyl-d-aspartate receptor-ionophore complex in Alzheimer brain

1991 • 63 citations

Dopamine release in the prefrontal cortex during stress is reduced by the local activation of glutamate receptors

2001 • 59 citations

Anxiolytic effect of glycine antagonists microinjected into the dorsal periaqueductal grey

1994 • 58 citations

New evidence for the antidepressant activity of MK-801, a non-competitive antagonist of NMDA receptors.

1993 • 53 citations

Striatal glutamate release during novelty exposure-induced hyperactivity in olfactory bulbectomized rats

2000 • 51 citations

The neurobiological basis of mixed depression-anxiety states.

1993 • 37 citations

The Relationship of Anxiety to Depression

1982 • 31 citations

Effects of D-cycloserine and cycloleucine, ligands for the NMDA-associated strychnine-insensitive glycine site, on brain-stimulation reward and spontaneous locomotion

1990 • 30 citations

NMDA receptors modulate long-term habituation to spatial novelty: Dose- and genotype-dependent differential effects of posttrial MK-801 and CPP in rats

1993 • 29 citations

<scp>d</scp>‐Cycloserine Blocks the Effects of Ethanol and HA‐966 in Rats Tested in the Elevated Plus‐Maze

1997 • 29 citations

Anticonflict effect of the glycine B receptor partial agonist, D -cycloserine, in rats. Pharmacological analysis

2000 • 27 citations

Calcium antagonists in the olfactory bulbectomy animal model of depression: effect on the cortical NMDA receptor complex.

1996 • 11 citations

Effects of Repeated Cold Stress on Aversive Responses Produced by Intrathecal Excitatory Amino Acids in Rats.

1995 • 10 citations

Acute immobilization stress alters LH and ACTH release in response to administration of N-methyl-D,L-aspartic acid in peripubertal and adult male rats

1995 • 8 citations