Three-dimensional structure of human cytomegalovirus protease

PROCHECK: a program to check the stereochemical quality of protein structures

1993 • 23,689 citations

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

The Anatomy and Taxonomy of Protein Structure

1981 • 3,376 citations

Analytical molecular surface calculation

1983 • 2,454 citations

Crystallographic R Factor Refinement by Molecular Dynamics

1987 • 1,982 citations

Structure of the complex formed by bovine trypsin and bovine pancreatic trypsin inhibitor

1974 • 548 citations

Proteins Specified by Herpes Simplex Virus VIII. Characterization and Composition of Multiple Capsid Forms of Subtypes 1 and 2

1972 • 348 citations

The high‐resolution X‐ray crystal structure of the complex formed between subtilisin Carlsberg and eglin c, an elastase inhibitor from the leech Hirudo medicinalis

1987 • 289 citations

Identification and Characterization of a Herpes Simplex Virus Gene Product Required for Encapsidation of Virus DNA

1983 • 279 citations

The herpes simplex virus 1 gene encoding a protease also contains within its coding domain the gene encoding the more abundant substrate

1991 • 225 citations

A herpesvirus maturational proteinase, assemblin: identification of its gene, putative active site domain, and cleavage site.

1991 • 174 citations

Principles determining the structure of β-sheet barrels in proteins II. The observed structures

1994 • 129 citations

Herpesvirus proteinase: site-directed mutagenesis used to study maturational, release, and inactivation cleavage sites of precursor and to identify a possible catalytic site serine and histidine

1993 • 115 citations

Structure of wheat serine carboxypeptidase II at 3.5-A resolution. A new class of serine proteinase.

1990 • 105 citations

Synthetic “interface” peptides alter dimeric assembly of the HIV 1 and 2 proteases

1992 • 91 citations

Active Human Cytomegalovirus Protease Is a Dimer

1996 • 90 citations

Structure of wheat serine carboxypeptidase II at 3.5-A resolution. A new class of serine proteinase.

1990 • 87 citations

Expression and analysis of the human cytomegalovirus UL80-encoded protease: identification of autoproteolytic sites

1993 • 86 citations

Dimerization of the Human Cytomegalovirus Protease: Kinetic and Biochemical Characterization of the Catalytic Homodimer

1996 • 80 citations

Human cytomegalovirus maturational proteinase: expression in Escherichia coli, purification, and enzymatic characterization by using peptide substrate mimics of natural cleavage sites

1994 • 70 citations

Identification of the serine residue at the active site of the herpes simplex virus type 1 protease.

1994 • 62 citations

In vitro activity of the herpes simplex virus type 1 protease with peptide substrates.

1993 • 57 citations

Activity of two-chain recombinant human cytomegalovirus protease.

1994 • 56 citations

Assemblin, a herpes virus serine maturational proteinase and new molecular target for antivirals

1995 • 46 citations

Proteolytic activity of human cytomegalovirus UL80 protease cleavage site mutants

1994 • 46 citations

Interface Peptides as Structure-based Human Immunodeficiency Virus Reverse Transcriptase Inhibitors

1995 • 31 citations

Cloning and Sequence Analysis of Murine Cytomegalovirus Protease and Capsid Assembly Protein Genes

1994 • 26 citations

Human cytomegalovirus proteinase: candidate glutamic acid identified as third member of putative active-site triad

1995 • 24 citations