Treatment of advanced solid tumors with immunotoxin LMB–1: An antibody linked to Pseudomonas exotoxin

Mechanisms of heterogeneous distribution of monoclonal antibodies and other macromolecules in tumors: significance of elevated interstitial pressure.

1988 • 703 citations

Structure of exotoxin A of Pseudomonas aeruginosa at 3.0-Angstrom resolution.

1986 • 517 citations

Functional domains of pseudomonas exotoxin identified by deletion analysis of the gene expressed in E. coli

1987 • 449 citations

Phase I immunotoxin trial in patients with B-cell lymphoma.

1991 • 289 citations

B3(Fv)-PE38KDEL, a single-chain immunotoxin that causes complete regression of a human carcinoma in mice.

1991 • 219 citations

Activity of immunotoxins constructed with modified Pseudomonas exotoxin A lacking the cell recognition domain.

1988 • 147 citations

Characterization of monoclonal antibodies B1 and B3 that react with mucinous adenocarcinomas.

1991 • 140 citations

Phase I Study of an Anti-Breast Cancer Immunotoxin by Continuous Infusion: Report of a Targeted Toxic Effect Not Predicted by Animal Studies

1989 • 124 citations

Characterization of polyethylene glycol-modified L-asparaginase from Escherichia coli and its application to therapy of leukemia.

1986 • 80 citations

Immunotoxin Therapy for Cancer

1993 • 54 citations

Recombinant Toxins: New Therapeutic Agents for Cancer

1995 • 46 citations

Polyethylene glycol-modified chimeric toxin composed of transforming growth factor alpha and Pseudomonas exotoxin.

1993 • 43 citations

Treatment of B-cell lymphomas with combination of bispecific antibodies and saporin

1995 • 32 citations

Primate antibody response to immunotoxin: serological and computer-aided analysis of epitopes on a truncated form of Pseudomonas exotoxin

1994 • 26 citations