Mechanisms of dendritic cell function

Murine epidermal Langerhans cells mature into potent immunostimulatory dendritic cells in vitro.

1985 • 1,141 citations

The Basis for the Immunoregulatory Role of Macrophages and Other Accessory Cells

1987 • 1,040 citations

Restoration of immunogenicity to passenger cell-depleted kidney allografts by the addition of donor strain dendritic cells.

1982 • 807 citations

Demonstration and characterization of Ia-positive dendritic cells in the interstitial connective tissues of rat heart and other tissues, but not brain.

1981 • 589 citations

Granulocyte/macrophage colony-stimulating factor and interleukin 1 mediate the maturation of murine epidermal Langerhans cells into potent immunostimulatory dendritic cells.

1988 • 565 citations

Presentation of exogenous protein antigens by dendritic cells to T cell clones. Intact protein is presented best by immature, epidermal Langerhans cells.

1989 • 542 citations

Epidermal Langerhans cells bear Fc and C3 receptors

1977 • 541 citations

Langerhans' cells, veiled cells, and interdigitating cells in the mouse recognized by a monoclonal antibody.

1986 • 478 citations

T Cell Selection in the Thymus

1988 • 405 citations

Cotransfection of ICAM-1 and HLA-DR reconstitutes human antigen-presenting cell function in mouse L cells

1989 • 389 citations

Human dendritic cells. Enrichment and characterization from peripheral blood

1982 • 389 citations

The mononuclear phagocyte system of the mouse defined by immunohistochemical localization of antigen F4/80. Relationship between macrophages, Langerhans cells, reticular cells, and dendritic cells in lymphoid and hematopoietic organs.

1983 • 386 citations

Resting and sensitized T lymphocytes exhibit distinct stimulatory (antigen-presenting cell) requirements for growth and lymphokine release.

1984 • 346 citations

A Distinct Endothelial Cell Recognition System That Controls Lymphocyte Traffic into Inflamed Synovium

1986 • 317 citations

An immunohistological analysis of lymphocyte subpopulations and their microenvironment in the synovial membranes of patients with rheumatoid arthritis using monoclonal antibodies.

1982 • 273 citations

Dendritic cells are accessory cells for the development of anti-trinitrophenyl cytotoxic T lymphocytes.

1980 • 265 citations

Involvement of a Leukocyte Adhesion Receptor (LFA-1) in HIV-Induced Syncytium Formation

1989 • 264 citations

Primary stimulation by dendritic cells induces antiviral proliferative and cytotoxic T cell responses in vitro.

1989 • 260 citations

Direct activation of CD8+ cytotoxic T lymphocytes by dendritic cells.

1987 • 237 citations

Migration patterns of dendritic cells in the mouse. Homing to T cell-dependent areas of spleen, and binding within marginal zone.

1988 • 226 citations

Dendritic cells and the initiation of contact sensitivity to fluorescein isothiocyanate.

1986 • 221 citations

Interleukin 1 enhances T-dependent immune responses by amplifying the function of dendritic cells.

1987 • 215 citations

Accessory cell-T lymphocyte interactions. Antigen-dependent and -independent clustering.

1986 • 205 citations

Isolation and characterization of human tonsil dendritic cells.

1988 • 201 citations

Langerhans Cells as Macrophages in Skin and Lymhphoid Organs

1980 • 195 citations

On the interdigitating cells in the thymus-dependent area of the rat spleen: A relation between the mononuclear phagocyte system and T-lymphocytes

1974 • 181 citations

Human dendritic cells: major stimulators of the autologous and allogeneic mixed leucocyte reactions.

1982 • 168 citations

Functional anatomy of lymph nodes. II. Peripheral lymph‐borne mononuclear cells

1978 • 164 citations

Dendritic cells from human tissues express receptors for the immunoregulatory vitamin D3 metabolite, dihydroxycholecalciferol.

1987 • 158 citations

Dendritic cells induce T cell proliferation to synthetic antigens under Ir gene control.

1980 • 147 citations

Accessory cell requirements for the mixed-leukocyte reaction and polyclonal mitogens, as studied with a new technique for enriching blood dendritic cells

1988 • 147 citations

Successful transplantation across major histocompatibility barrier of deoxyguanosine-treated embryonic thymus expressing class II antigens

1984 • 138 citations

Identification of immunostimulatory dendritic cells in the synovial effusions of patients with rheumatoid arthritis.

1985 • 128 citations

Suppression of immune responses by dendritic cells infected with HIV.

1989 • 115 citations

Dendritic cells of the mouse recognized by two monoclonal antibodies

1987 • 99 citations

Human tonsillar dendritic cell‐induced T cell responses: analysis of molecular mechanisms using monoclonal antibodies

1989 • 79 citations

Specific immune responses restored by alteration in carbohydrate chains of surface molecules on antigen‐presenting cells

1989 • 76 citations

A small number of anti-CD3 molecules on dendritic cells stimulate DNA synthesis in mouse T lymphocytes.

1989 • 68 citations

The cellular pathway of antigen presentation: biochemical and functional analysis of antigen processing in dendritic cells and macrophages.

1986 • 58 citations

Heterogeneity of stimulator cells in the murine mixed leukocyte response

1982 • 57 citations

Differential MHC class II expression on human peripheral blood monocytes and dendritic cells.

1988 • 57 citations

Accessory cell-dependent selection of specific T-cell functions

1983 • 52 citations

Stimulation with dendritic cells decreases or obviates the CD4+ helper cell requirement in cytotoxic T lymphocyte responses

1988 • 46 citations

The study of circulating lymphocytes in vivo: a personal view of artifice and artifact

1985 • 42 citations

Interleukin 1 production during accessory cell-dependent mitogenesis of T lymphocytes.

1989 • 42 citations

Membrane-associated IL 1-like activity on rat dendritic cells.

1986 • 41 citations

The role of CD44, CD45, CD45RO, CD46 and CD55 as potential anti‐adhesion molecules involved in the binding of human tonsillar T cells to phorbol 12‐myristate 13‐acetate‐differentiated U‐937 cells

1990 • 32 citations

Thy-1+ and Thy-1- natural killer cells. Only Thy-1- natural killer cells suppress dendritic cells.

1986 • 32 citations

Role of dendritic cells in the regulation of class I restricted cytotoxic T lymphocyte responses.

1988 • 31 citations

Heterogeneity of accessory cells interacting with T-helper clones.

1986 • 24 citations

Induction of interleukin 1 alpha mRNA during the antigen-dependent interaction of sensitized T lymphoblasts with macrophages.

1988 • 22 citations

Endopeptidase activities associated with the plasma membrane compartment of an antigen-presenting B cell.

1989 • 21 citations

Factor-induced differentiation and activation of macrophages

1986 • 16 citations

Neuraminidase-treated macrophages stimulate allogenic CD8+ T cells in the presence of exogenous interleukin 2.

1988 • 14 citations

Signal delivery by physical interaction and soluble factors from accessory cells in the induction of receptor-mediated T-cell proliferation. Synergistic effect of BSF-2/IL-6 and IL-1.

1989 • 14 citations

A cell-free model system for the study of antigen processing

1989 • 11 citations

Immunosuppression as a physiological homeostatic mechanism

1984 • 11 citations

[24] Monoclonal antibodies to transferrin receptor and assay of their biological effects

1987 • 10 citations

Phorbol Ester-Induced Loss of Membrane Sialic Acid: Implications for Tumor Cytolysis by Natural Killer Cells

1989 • 8 citations

Mapping the Neu-1 locus to the major histocompatibility complex (RT1) in the rat

1987 • 6 citations