Signal delivery by physical interaction and soluble factors from accessory cells in the induction of receptor-mediated T-cell proliferation. Synergistic effect of BSF-2/IL-6 and IL-1.

Establishment and characterization of a human histiocytic lymphoma cell line (U‐937)

1976 • 2,468 citations

Interferon beta 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells.

1987 • 1,667 citations

A monoclonal antibody (anti-Tac) reactive with activated and functionally mature human T cells. I. Production of anti-Tac monoclonal antibody and distribution of Tac (+) cells.

1981 • 1,366 citations

Production of hybridoma growth factor by human monocytes

1987 • 1,133 citations

Purification to homogeneity and characterization of human B-cell differentiation factor (BCDF or BSFp-2).

1985 • 679 citations

B cell stimulating factor 2/interleukin 6 is a costimulant for human thymocytes and T lymphocytes.

1988 • 537 citations

Multiple actions of interleukin 6 within a cytokine network

1988 • 536 citations

Growth of a cloned helper T cell line induced by a monoclonal antibody specific for the antigen receptor: interleukin 1 is required for the expression of receptors for interleukin 2.

1984 • 529 citations

Triggering of the T3-Ti antigen-receptor complex results in clonal T-cell proliferation through an interleukin 2-dependent autocrine pathway.

1984 • 506 citations

B-cell-stimulatory factor 2 (beta 2 interferon) functions as a second signal for interleukin 2 production by mature murine T cells.

1987 • 357 citations

Phenotype of the accessory cell necessary for mitogen-stimulated T and B cell responses in human peripheral blood: delineation by its sensitivity to the lysosomotropic agent, L-leucine methyl ester.

1983 • 353 citations

Molecular cloning and expression of hybridoma growth factor in Escherichia coli.

1987 • 238 citations

Interleukin 1 enhances T-dependent immune responses by amplifying the function of dendritic cells.

1987 • 215 citations

Human β ₂ Interferon and B-Cell Differentiation Factor BSF-2 Are Identical

1987 • 204 citations

Phytohaemagglutinin activation of T cells through the sheep red blood cell receptor

1985 • 200 citations

The events of primary T cell activation can be staged by use of Sepharose-bound anti-T3 (64.1) monoclonal antibody and purified interleukin 1.

1985 • 189 citations

Synergistic activation of human t cells by interleukin 1 and interleukin 6

1988 • 153 citations

Antigen presentation by human monocytes: evidence for stimulant processing and requirement for interleukin 1.

1983 • 131 citations

Interferon-beta 2/interleukin 6 is a co-stimulant for human T lymphocytes.

1988 • 125 citations

The immunosuppressive activity of L-leucyl-L-leucine methyl ester: selective ablation of cytotoxic lymphocytes and monocytes.

1986 • 117 citations

T cell receptor triggering induces responsiveness to interleukin 1 and interleukin 2 but does not lead to T cell proliferation.

1986 • 113 citations

Human helper T cell factor(s) (ThF). II. Induction of IgG production in B lymphoblastoid cell lines and identification of T cell-replacing factor- (TRF) like factor(s).

1982 • 108 citations

Absence of antiviral activity in recombinant B cell stimulatory factor 2 (BSF-2)

1988 • 87 citations

The murine IL 2 receptor. III. Cellular requirements for the induction of IL 2 receptor expression on T cell subpopulations.

1985 • 79 citations

Requirement for delivery of signals by physical interaction and soluble factors from accessory cells in the induction of receptor-mediated T cell proliferation. Effectiveness of IFN-gamma modulation of accessory cells for physical interaction with T cells.

1989 • 63 citations

An antigen receptor-driven, interleukin 2-independent pathway for proliferation of murine cytolytic T lymphocyte clones.

1986 • 58 citations

Dissection of the functions of antigen-presenting cells in the induction of T cell activation.

1985 • 57 citations

Interaction between the CD45 antigen and phytohemagglutinin. Inhibitory effect on the lectininduced T cell proliferation by anti‐CD45 monoclonal antibody

1987 • 57 citations

Isolation and partial characterization of concanavalin A receptors on cloned cytotoxic T lymphocytes.

1984 • 51 citations

Evidence for IL-2 independent proliferation in human T cells.

1988 • 51 citations

Activation requirements for normal T cells: accessory cell-dependent and -independent stimulation by anti-receptor antibodies.

1986 • 46 citations

Characterization of a novel murine T cell-activating factor.

1987 • 40 citations

Dissection of the Role of Macrophages in Triggering T Lymphocytes for Interleukin 2 Production by Monoclonal Antibody OKT3

1986 • 5 citations