CD8+ EFFECTOR CELLS RESPONDING TO RESIDUAL CLASS I ANTIGENS, WITH HELP FROM CD4+ CELLS STIMULATED INDIRECTLY, CAUSE REJECTION OF ???MAJOR HISTOCOMPATIBILITY COMPLEX-DEFICIENT??? SKIN GRAFTS1

Characterization of the murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK1.5: similarity of L3T4 to the human Leu-3/T4 molecule.

1983 • 1,307 citations

Antigen-inducible, H-2-restricted, interleukin-2-producing T cell hybridomas. Lack of independent antigen and H-2 recognition

1981 • 1,048 citations

Hybridoma cell lines secreting monoclonal antibodies to mouse H-2 and Ia antigens.

1980 • 850 citations

IgG or IgM monoclonal antibodies reactive with different determinants on the molecular complex bearing Lyt 2 antigen block T cell-mediated cytolysis in the absence of complement.

1980 • 835 citations

The Technique of Free Skin Grafting in Mammals

1951 • 760 citations

Helper activity is required for the in vivo generation of cytotoxic T lymphocytes

1982 • 511 citations

Establishment of Monoclonal Anti-Nk-1.1 Antibody

1984 • 360 citations

Mice lacking major histocompatibility complex class I and class II molecules.

1993 • 259 citations

Indirect recognition by helper cells can induce donor-specific cytotoxic T lymphocytes in vivo.

1994 • 227 citations

Phenotype, specificity, and function of T cell subsets and T cell interactions involved in skin allograft rejection.

1987 • 198 citations

Coronary atherosclerosis in transplanted mouse hearts. I. Time course and immunogenetic and immunopathological considerations.

1994 • 149 citations

Functionally conformed free class I heavy chains exist on the surface of beta 2 microglobulin negative cells.

1992 • 146 citations

Three‐cell‐type clusters of T cells with antigen‐presenting cells best explain the epitope linkage and noncognate requirements of the in vivo cytolytic response

1987 • 141 citations

Class II-positive hematopoietic cells cannot mediate positive selection of CD4+ T lymphocytes in class II-deficient mice.

1993 • 92 citations

INDEFINITE SURVIVAL OF MHC CLASS I-DEFICIENT MURINE PANCREATIC ISLET ALLOGRAFTS

1992 • 86 citations

Cross‐blocking studies with monoclonal antibodies against I‐A molecules of haplotypes b, d and k

1982 • 81 citations

Cellular basis of skin allograft rejection across a class I major histocompatibility barrier in mice depleted of CD8+ T cells in vivo.

1991 • 76 citations

Clonal deletion of V beta 5+ T cells by transgenic I-E restricted to thymic medullary epithelium.

1993 • 76 citations

Survival of MHC-deficient mouse heterotopic cardiac allografts.

1995 • 70 citations

Major histocompatibility complex class I-specific and -restricted killing of beta 2-microglobulin-deficient cells by CD8+ cytotoxic T lymphocytes.

1992 • 70 citations

T cells cooperating in the induction of delayed-type hypersensitivity act via the linked recognition of antigenic determinants.

1982 • 69 citations

Improved renal function in mouse kidney allografts lacking MHC class I antigens.

1993 • 63 citations

Survival Of Mhc-Deficient Mouse Heterotopic Cardiac Allografts

1995 • 60 citations

In Vivo use of monoclonal antibodies against murine T cell antigens

1989 • 56 citations

Evidence for involvement of dual-function T cells in rejection of MHC class I disparate skin grafts. Assessment of MHC class I alloantigens as in vivo helper determinants.

1988 • 47 citations

Avidity for antigen can influence the helper dependence of CD8+ T lymphocytes.

1993 • 43 citations

Major Histocompatibility Complex Class I Deficiency Prolongs Islet Allograft Survival

1993 • 41 citations

USE OF DONOR β2-MICROGLOBULIN-DEFICIENT TRANSGENIC MOUSE LIVER CELLS FOR ISOGRAFTS, ALLOGRAFTS, AND XENOGRAFTS

1993 • 39 citations

T-cell subsets, bm mutants, and the mechanisms of allogeneic skin graft rejection

1989 • 36 citations

PREVENTION OF ALLOANTIBODY FORMATION AFTER SKIN GRAFTING WITHOUT PROLONGATION OF GRAFT SURVIVAL

1988 • 35 citations

Graft rejection by T cells not restricted by conventional major histocompatibility complex molecules

1993 • 30 citations

Effector cells must recognize antigens expressed in the graft to cause efficient skin graft rejection in SCID mice.

1995 • 26 citations

Genetically engineered grafts to study xenoimmunity: a role for indirect antigen presentation in the destruction of major histocompatibility complex antigen deficient xenografts.

1994 • 25 citations

Immunologically nonspecific mechanisms of tissue destruction in the rejection of skin grafts.

1994 • 20 citations

CURRENT LIMITATIONS TO USE OF MAJOR HISTOCOMPATIBILITY COMPLEX TRANSGENIC DONORS FOR ISLET TRANSPLANTATION

1994 • 3 citations

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