Processing of the Transforming Growth Factor β Type I and II Receptors

Mechanism of activation of the TGF-β receptor

1994 • 2,298 citations

TGFβ signals through a heteromeric protein kinase receptor complex

1992 • 1,519 citations

Expression cloning of the TGF-β type II receptor, a functional transmembrane serine/threonine kinase

1992 • 1,071 citations

Cloning of a TGF$beta; type I receptor that forms a heteromeric complex with the TGF$beta; type II receptor

1993 • 779 citations

Expression cloning and characterization of the TGF-β type III receptor

1991 • 638 citations

Genetic changes in the transforming growth factor beta (TGF-beta) type II receptor gene in human gastric cancer cells: correlation with sensitivity to growth inhibition by TGF-beta.

1994 • 431 citations

Inactivation of the Type II Receptor Reveals Two Receptor Pathways for the Diverse TGF-β Activities

1993 • 388 citations

Expression of transforming growth factor beta type II receptor leads to reduced malignancy in human breast cancer MCF-7 cells

1994 • 325 citations

Responsiveness to transforming growth factor-beta (TGF-beta) restored by genetic complementation between cells defective in TGF-beta receptors I and II

1991 • 252 citations

The types II and III transforming growth factor-beta receptors form homo-oligomers.

1994 • 199 citations

A WD-domain protein that is associated with and phosphorylated by the type II TGF-β receptor

1995 • 196 citations

Glucocorticoid regulation of transforming growth factor beta 1 activity and binding in osteoblast-enriched cultures from fetal rat bone.

1991 • 163 citations

Complementation between kinase-defective and activation-defective TGF-beta receptors reveals a novel form of receptor cooperativity essential for signaling.

1996 • 158 citations

Resistance to transforming growth factor beta and activin due to reduced receptor expression in human breast tumor cell lines.

1995 • 155 citations

Homomeric interactions between type II transforming growth factor-beta receptors.

1994 • 137 citations

Identification of Important Regions in the Cytoplasmic Juxtamembrane Domain of Type I Receptor That Separate Signaling Pathways of Transforming Growth Factor-β

1996 • 125 citations

Growth stimulation of human breast cancer cells with anti-transforming growth factor beta antibodies: evidence for negative autocrine regulation by transforming growth factor beta.

1990 • 118 citations

Biochemical evidence for the autophosphorylation and transphosphorylation of transforming growth factor beta receptor kinases.

1995 • 116 citations

Biosynthesis of the Type I and Type II TGF-β Receptors

1997 • 83 citations

Induction and Autocrine Receptor Binding of Transforming Growth Factor-β2 during Terminal Differentiation of Primary Mouse Keratinocytes

1990 • 81 citations

Phosphorylation-dependent Interaction of the Cytoplasmic Domains of the Type I and Type II Transforming Growth Factor-β Receptors

1995 • 80 citations

Transforming growth factor β and cancer

1995 • 73 citations

Transforming growth factors-beta as regulators of cellular growth and phenotype.

1992 • 51 citations

Rapid Flux in Transforming Growth Factor-β Receptors on Bone Cells

1996 • 50 citations

Growth suppression by transforming growth factor β1 of human small-cell lung cancer cell lines is associated with expression of the type II receptor

1994 • 47 citations

Regulation of transforming growth factor beta receptors in H-ras oncogene-transformed rat intestinal epithelial cells.

1995 • 44 citations

Transforming Growth Factor-β System and Its Regulation by Members of the Steroid-Thyroid Hormone Superfamily

1996 • 31 citations

Association of Latent Transforming Growth Factor-.BETA. to Fibroblast Extracellular Matrix-An Insight to Proteolytic Activation.

1995 • 3 citations