Anandamide activates human platelets through a pathway independent of the arachidonate cascade

Isolation and Structure of a Brain Constituent That Binds to the Cannabinoid Receptor

1992 • 5,504 citations

Aggregation of Blood Platelets by Adenosine Diphosphate and its Reversal

1962 • 4,273 citations

Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents

1996 • 1,773 citations

Formation and inactivation of endogenous cannabinoid anandamide in central neurons

1994 • 1,564 citations

Control of pain initiation by endogenous cannabinoids

1998 • 1,044 citations

Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein

1994 • 854 citations

Functional Role of High-Affinity Anandamide Transport, as Revealed by Selective Inhibition

1997 • 806 citations

Mast cells express a peripheral cannabinoid receptor with differential sensitivity to anandamide and palmitoylethanolamide.

1995 • 625 citations

Defective platelet activation in Gαq-deficient mice

1997 • 566 citations

Inhibition of NF- B DNA Binding by Nitric Oxide

1996 • 479 citations

Molecular Basis for ADP-induced Platelet Activation

1998 • 463 citations

Molecular Basis for ADP-induced Platelet Activation

1998 • 446 citations

Molecular characterization of human and mouse fatty acid amide hydrolases

1997 • 426 citations

Identification and Characterization of a Prostaglandin Transporter

1995 • 400 citations

Biosynthesis, Uptake, and Degradation of Anandamide and Palmitoylethanolamide in Leukocytes

1997 • 372 citations

Production and physiological actions of anandamide in the vasculature of the rat kidney.

1997 • 363 citations

Accumulation of N‐Arachidonoylethanolamine (Anandamide) into Cerebellar Granule Cells Occurs via Facilitated Diffusion

1997 • 337 citations

‘Endocannabinoids’ and other fatty acid derivatives with cannabimimetic properties: biochemistry and possible physiopathological relevance

1998 • 317 citations

Activation of peripheral CB1 cannabinoid receptors in haemorrhagic shock

1997 • 288 citations

Characterization of the kinetics and distribution of N-arachidonylethanolamine (anandamide) hydrolysis by rat brain

1995 • 234 citations

Two novel classes of neuroactive fatty acid amides are substrates for mouse neuroblastoma ‘anandamide amidohydrolase’

1995 • 199 citations

Anandamide Hydrolysis by Human Cells in Culture and Brain

1998 • 196 citations

Increased platelet sensitivity to ADP in mice lacking platelet-type 12-lipoxygenase

1998 • 134 citations

Hydrogen peroxide has a role in the aggregation of human platelets

1985 • 121 citations

Human Platelets and Polymorphonuclear Leukocytes Synthesize Oxygenated Derivatives of Arachidonylethanolamide (Anandamide): Their Affinities for Cannabinoid Receptors and Pathways of Inactivation

1998 • 118 citations

The ATP- and CoA-independent synthesis of arachidonoylethanolamide. A novel mechanism underlying the synthesis of the endogenous ligand of the cannabinoid receptor.

1994 • 116 citations

Autoimmunovascular regulation: morphine and ancondamide and ancondamide stimulated nitric oxide release

1998 • 100 citations

Potentiation of anandamide hypotension by the transport inhibitor, AM404

1997 • 94 citations

Isotope dilution GC/MS determination of anandamide and other fatty acylethanolamides in rat blood plasma

1998 • 94 citations

Cytotoxic effect of HIV-1 coat glycoprotein gp120 on human neuroblastoma CHP100 cells involves activation of the arachidonate cascade

1998 • 59 citations

Death of cultured human neuroblastoma cells induced by HIV-1 gp120 is prevented by NMDA receptor antagonists and inhibitors of nitric oxide and cyclooxygenase

1995 • 58 citations

Anandamide and endothelium-derived hyperpolarizing factor act via a common vasorelaxant mechanism in rat mesentery

1998 • 51 citations

With Anandamide as Substrate Plant 5-Lipoxygenases Behave like 11-Lipoxygenases

1998 • 41 citations

Membrane Modifications in Human Erythroleukemia K562 Cells During Induction of Programmed Cell Death by Transforming Growth Factor β1 or Cisplatin

1996 • 38 citations

Dioxygenation of N‐linoleoyl amides by soybean lipoxygenase‐1

1997 • 26 citations

The effect of hydroxylation of linoleoyl amides on their cannabinomimetic properties

1997 • 23 citations

An investigation on the quinoprotein nature of some fungal and plant oxidoreductases.

1991 • 13 citations

Variability of the thrombin- and ADP-induced Ca2+ response among human platelets measured using fluo-3 and fluorescent videomicroscopy

1996 • 7 citations