Collaboration of helper and cytotoxic T lymphocytes

Characterization of the Murine Antigenic Determinant, Designated L3T4a, Recognized by Monoclonal Antibody GK 1.5: Expression of L3T4a by Functional T Cell Clones Appears to Correlate Primarily with Class II MHC Antigen‐Reactivity

1983 • 1,040 citations

Production of a monoclonal antibody to and molecular characterization of B-cell stimulatory factor-1

1985 • 749 citations

Normal development and function of CD8+ cells but markedly decreased helper cell activity in mice lacking CD4

1991 • 695 citations

Establishment and Characterization of BALB/c Lymphoma Lines with B Cell Properties

1979 • 677 citations

The interferon system. A bird's eye view of its biochemistry.

1992 • 633 citations

In vivo priming of virus-specific cytotoxic T lymphocytes with synthetic lipopeptide vaccine

1989 • 632 citations

Helper activity is required for the in vivo generation of cytotoxic T lymphocytes

1982 • 511 citations

Identification of a membrane-associated interleukin 1 in macrophages.

1985 • 487 citations

Exact prediction of a natural T cell epitope

1991 • 455 citations

Fine Specificity Analysis with Monoclonal Antibodies of Antigens Controlled by the Major Histocompatibility Complex and by the Qa/TL Region in Mice

1979 • 451 citations

IL-10: a novel cytotoxic T cell differentiation factor.

1991 • 391 citations

Monoclonal antibody to murine gamma interferon inhibits lymphokine-induced antiviral and macrophage tumoricidal activities.

1984 • 386 citations

Activated B cells express receptors for, and proliferate in response to, pure interleukin 2.

1984 • 361 citations

The B-cell surface protein CD72/Lyb-2 is the ligand for CDS

1991 • 305 citations

Receptor-directed focusing of lymphokine release by helper T cells

1988 • 284 citations

Interleukin 7 is a T-cell growth factor.

1989 • 206 citations

Regulation of cytolytic T-lymphocyte generation by B-cell stimulatory factor

1987 • 193 citations

Generation of activated killer (AK) cells by recombinant interleukin 2 (rIL 2) in collaboration with interferon-gamma (IFN-gamma).

1985 • 184 citations

A differentiation factor required for the expression of cytotoxic T-cell function

1982 • 163 citations

Interleukin 7 enhances cytolytic T lymphocyte generation and induces lymphokine-activated killer cells from human peripheral blood.

1990 • 160 citations

Production of Interferon-Gamma during Infection of Mice with Plasmodium chabaudi chabaudi

1989 • 157 citations

Participation of lymphocyte activating factor (Interleukin 1) in the induction of cytotoxic T cell responses.

1980 • 157 citations

Monoclonal antibodies against murine gamma interferon.

1984 • 153 citations

Macrophages as accessory cells for class I MHC-restricted immune responses.

1991 • 148 citations

In vivo induction of cytotoxic T cell response by a free synthetic peptide requires CD4+ T cell help.

1991 • 146 citations

Three‐cell‐type clusters of T cells with antigen‐presenting cells best explain the epitope linkage and noncognate requirements of the in vivo cytolytic response

1987 • 141 citations

Interleukin 2 is both necessary and sufficient for the growth and differentiation of lectin-stimulated cytolytic T lymphocyte precursors.

1985 • 141 citations

Dissection of the proliferative and differentiative signals controlling murine cytotoxic T lymphocyte responses.

1982 • 135 citations

Recombinant interferon-gamma induces interleukin 2 receptors on human peripheral blood monocytes.

1986 • 126 citations

A requirement for antigen-specific helper T cells in the generation of cytotoxic T cells from thymocyte precursors.

1977 • 122 citations

Distinct Ir genes for helper and killer cells in the cytotoxic response to H-Y antigen.

1979 • 122 citations

Interferon: a cytotoxic T lymphocyte differentiation signal

1986 • 119 citations

The role of interleukin-2 (IL-2) in the differentiatin of cytotoxic T cells: the effect of monoclonal anti-IL-2 antibody and absorption with IL-2 dependent T cell lines.

1981 • 113 citations

Regulation of the immune response by subclasses of T lymphocytes. I. Interactions between pre‐killer T cells and regulatory T cells obtained from peripheral lymphoid tissues of mice

1975 • 108 citations

T helper epitopes enhance the cytotoxic response of mice immunized with MHC class I-restricted malaria peptides

1992 • 97 citations

Cognate peptides induce self-destruction of CD8+ cytolytic T lymphocytes.

1990 • 96 citations

Cytotoxic T-lymphocyte activation involves a cascade of signalling and adhesion events

1992 • 94 citations

Cooperation between Helper T Cells and Cytotoxic T Lymphocyte Precursors

1988 • 86 citations

Signal requirements in the step-wise functional maturation of cytotoxic T lymphocytes

1987 • 84 citations

Relationship of macrophage Ia and membrane IL 1 expression to antigen presentation.

1985 • 82 citations

IL-2 and IL-6 synergize to augment the pore-forming protein gene expression and cytotoxic potential of human peripheral blood T cells.

1990 • 77 citations

Monoclonal antibodies to interferon-gamma inhibit interleukin 2-dependent induction of growth and maturation in lectin/antigen-reactive cytolytic T lymphocyte precursors.

1986 • 61 citations

Is the T-cell receptor involved in T-cell killing?

1986 • 60 citations

Cellular interactions in the generation of cytolytic T lymphocyte responses: role of Ia-positive splenic adherent cells in presentation in H-2 antigen.

1980 • 58 citations

Activation of cytotoxic T lymphocytes requires at least two spleen cell-derived helper factors besides interleukin 2.

1983 • 56 citations

IL-7 regulation of cytotoxic lymphocytes: Pore-forming protein gene expression, interferon-γ production, and cytotoxicity of human peripheral blood lymphocyte subsets

1991 • 52 citations

Mechanisms of induction of primary virus‐specific cytotoxic T lymphocyte responses

1992 • 49 citations

Three different signals are required for the induction of cytolytic T lymphocytes from resting precursors.

1983 • 43 citations

Enhancement of in vivo cell-mediated immune responses by three distinct cytokines.

1990 • 41 citations

The IL‐2 mediated amplification of cellular cytotoxicity

1991 • 38 citations

Antigen stimulation of cytolytic T lymphocyte precursors: minimal requirements for growth and acquisition of cytolytic activity

1985 • 35 citations

Requirement for three distinct lymphokines for the induction of cytotoxic T lymphocytes from thymocytes.

1986 • 33 citations

An exact comparison between the efficiency of two‐ and three‐cell‐type clusters in mediating helper activity

1990 • 33 citations

Accessory Cell Requirements for the Generation of Cytolytic T Lymphocytes

1979 • 28 citations

Effects of cognate peptides on cytolytic and proliferative activities of cloned cytotoxic T lymphocytes

1992 • 23 citations

Helper effects required during in vivo priming for a cytolytic response to the H-Y antigen in nonresponder mice.

1985 • 22 citations

A novel approach to the induction of specific cytolytic T cells in vivo

1990 • 19 citations

Expression and role of interleukin‐2 receptor β chain on CD4⁻CD8⁺ T cell receptor αβ⁺ cells

1992 • 16 citations

Problems in the Physiology of Class I and Class II MHC Molecules, and of CD45

1989 • 12 citations

Use of New HPLC Resins to Solve Old Problems

1986 • 11 citations

A novel approach to the induction of specific cytolytic T cells in vivo

1990 • 11 citations

Fine specificity analysis of lactate dehydrogenase B‐specific proliferating T cell clones: implications for the mechanism of alloreactivity

1985 • 9 citations

Aortenbogen-DSA (peripher-venös)

1989 • 3 citations

Cited By (0)

Loading...