Dissection of the proliferative and differentiative signals controlling murine cytotoxic T lymphocyte responses.

T cell growth factor receptors. Quantitation, specificity, and biological relevance

1981 • 1,087 citations

T‐Cell Growth Factor

1980 • 917 citations

Cyclosporin A mediates immunosuppression of primary cytotoxic T cell responses by impairing the release of interleukin 1 and interleukin 2

1981 • 632 citations

Thymoma production of T cell growth factor (Interleukin 2).

1980 • 487 citations

Two distinct factors are required for induction of T-cell growth

1980 • 416 citations

T-T-cell interactions during the vitro cytotoxic allograft responses. I. Soluble products from activated Lyl+ T cells trigger autonomously antigen-primed Ly23+ T cells to cell proliferation and cytolytic activity.

1978 • 330 citations

Cell Mediated Immunity: Separation of Cells Involved in Recognitive and Destructive Phases

1973 • 227 citations

Cytotoxic Effects of Antigen- and Mitogen-Induced T Cells on Various Targets

1975 • 224 citations

Immune interferon release when a cloned cytotoxic T-cell line meets its correct influenza-infected target cell

1982 • 202 citations

B cell helper factors. I. Requirement for both interleukin 2 and another 40,000 mol wt factor.

1981 • 159 citations

Biochemical and biologic characterization of lymphocyte regulatory molecules. III. The isolation and phenotypic characterization of Interleukin-2 producing T cell lymphomas.

1980 • 125 citations

A requirement for antigen-specific helper T cells in the generation of cytotoxic T cells from thymocyte precursors.

1977 • 122 citations

Regulation of the immune response by subclasses of T lymphocytes. I. Interactions between pre‐killer T cells and regulatory T cells obtained from peripheral lymphoid tissues of mice

1975 • 108 citations

The differentiation of cytotoxic T cells in vitro. I. Amplifying factor(s) in the primary response is Lyt 1 + cell dependent.

1979 • 92 citations

Quantitative studies on the precursors of cytotoxic lymphocytes. VI. Second signal requirements of specifically activated precursors isolated 12 h after stimulation.

1980 • 48 citations

Generation of alloreactive cytotoxic T lymphocytes: production of T cell and macrophage helper factors in addition to IL 1 and IL 2 by peritoneal cells from mice immunized to Listeria monocytogenes.

1981 • 39 citations

Interleukin 2 is not sufficient as helper component for the activation of cytotoxic T lymphocytes but synergizes with a late helper effect that is provided by irradiated I-region-incompatible stimulator cells.

1982 • 36 citations

Cell-Mediated Immune Responses in vitro: Interaction of Thymus-Derived Cells during Cytotoxic Allograft Responses in vitro

1973 • 23 citations

Triggering of affinity-enriched B cells. Analysis of B cell stimulation by antigen-specific helper factor or lipopolysaccharide. I. Dissection into proliferative and differentiative signals.

1982 • 13 citations

Functional Analysis of I1-2 Produced by T-Cell Hybridomas: I1-2 Promotes T-Cell Growth But Does Not Mediate T-Cell or B-Cell Maturation and Differentiation

1982 • 3 citations