Effect of the NMDA antagonist MK-801 on MPTP-induced parkinsonism in the monkey

Parkinsonism

1967 • 11,463 citations

The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist.

1986 • 1,814 citations

Selective nigral toxicity after systemic administration of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyrine (MPTP) in the squirrel monkey

1984 • 913 citations

Neural mechanisms underlying parkinsonian symptoms based upon regional uptake of 2-deoxyglucose in monkeys exposed to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

1989 • 455 citations

Primate models of dyskinesia: The experimental approach to the study of basal ganglia-related involuntary movement disorders

1987 • 276 citations

Anatomy and Physiology of the Subthalamic Nucleus: A Driving Force of the Basal Ganglia

1987 • 206 citations

The Neurotoxicity of 1-Methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine in the Monkey and Man

1984 • 142 citations

Levodopa-induced dyskinesia and response fluctuations in primates rendered parkinsonian with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)

1987 • 113 citations

Dyskinesia in the primate following injection of an excitatory amino acid antagonist into the medial segment of the globus pallidus

1989 • 75 citations

Induction of chorea and dystonia in parkinsonian primates

1990 • 68 citations