Detection of HIV-RNA-positive monocytes in peripheral blood of HIV-positive patients by simultaneous flow cytometric analysis of intracellular HIV RNA and cellular immunophenotype

Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

1995 • 4,310 citations

HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

1996 • 4,184 citations

CD14, a Receptor for Complexes of Lipopolysaccharide (LPS) and LPS Binding Protein

1990 • 4,041 citations

1993 Revised Classification System for HIV Infection and Expanded Surveillance Case Definition for AIDS Among Adolescents and Adults

1993 • 3,829 citations

HIV-1 Dynamics in Vivo: Virion Clearance Rate, Infected Cell Life-Span, and Viral Generation Time

1996 • 3,496 citations

Viral dynamics in human immunodeficiency virus type 1 infection

1995 • 3,277 citations

CC CKR5: A RANTES, MIP-1α, MIP-1β Receptor as a Fusion Cofactor for Macrophage-Tropic HIV-1

1996 • 2,735 citations

HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease

1993 • 1,822 citations

Massive covert infection of helper T lymphocytes and macrophages by HIV during the incubation period of AIDS

1993 • 1,450 citations

Change in Coreceptor Use Correlates with Disease Progression in HIV-1–Infected Individuals

1997 • 1,373 citations

Pathogenesis of human immunodeficiency virus infection

1993 • 835 citations

HIV-1 replication is controlled at the level of T cell activation and proviral integration.

1990 • 800 citations

Efficient isolation and propagation of human immunodeficiency virus on recombinant colony-stimulating factor 1-treated monocytes.

1988 • 785 citations

The Reservoir for HIV-1 in Human Peripheral Blood Is a T Cell That Maintains Expression of CD4

1989 • 732 citations

Tumor necrosis factor alpha induces expression of human immunodeficiency virus in a chronically infected T-cell clone.

1989 • 726 citations

Cellular targets of infection and route of viral dissemination after an intravaginal inoculation of simian immunodeficiency virus into rhesus macaques.

1996 • 705 citations

The monocyte differentiation antigen, CD14, is anchored to the cell membrane by a phosphatidylinositol linkage.

1988 • 654 citations

Molecular characterization of human immunodeficiency virus type 1 cloned directly from uncultured human brain tissue: identification of replication-competent and -defective viral genomes

1991 • 385 citations

Cells nonproductively infected with HIV-1 exhibit an aberrant pattern of viral RNA expression: A molecular model for latency

1990 • 371 citations

Reduction of HIV Concentration During Acute Infection: Independence from a Specific Immune Response

1996 • 335 citations

Monocytotropic human immunodeficiency virus type 1 (HIV-1) variants detectable in all stages of HIV-1 infection lack T-cell line tropism and syncytium-inducing ability in primary T-cell culture

1991 • 326 citations

CD4 percentage, CD4 number, and CD4:CD8 ratio in HIV infection: which to choose and how to use.

1989 • 311 citations

CD14^lowCD16^high: A cytokine‐producing monocyte subset which expands during human immunodeficiency virus infection

1995 • 287 citations

Increasing Viral Burden in CD4+ T Cells from Patients with Human Immunodeficiency Virus (HIV) Infection Reflects Rapidly Progressive Immunosuppression and Clinical Disease

1990 • 281 citations

Detection of HIV-1 DNA and Messenger RNA in Individual Cells by PCR-Driven in Situ Hybridization and Flow Cytometry

1993 • 270 citations

Increased susceptibility of differentiated mononuclear phagocytes to productive infection with human immunodeficiency virus-1 (HIV-1).

1992 • 220 citations

Syncytium-inducing (SI) phenotype suppression at seroconversion after intramuscular inoculation of a non-syncytium-inducing/SI phenotypically mixed human immunodeficiency virus population

1995 • 177 citations

Reducing cellular autofluorescence in flow cytometry: an in situ method.

1997 • 119 citations

Latent HIV-1 infection in enriched populations of blood monocytes and T cells from seropositive patients.

1991 • 111 citations

A family of serine proteases expressed exclusively in myelo-monocytic cells specifically processes the nuclear factor-kappa B subunit p65 in vitro and may impair human immunodeficiency virus replication in these cells.

1994 • 102 citations

Functional studies of epidermal Langerhans cells and blood monocytes in HIV-infected persons.

1995 • 96 citations

Mononuclear Phagocytes as Targets, Tissue Reservoirs, and Immunoregulatory Cells in Human Immunodeficiency Virus Disease

1992 • 87 citations

Changes in the viral mRNA expression pattern correlate with a rapid rate of CD4+ T-cell number decline in human immunodeficiency virus type 1-infected individuals

1995 • 86 citations

Dynamics of molecular parameters of human immunodeficiency virus type 1 activity in vivo

1994 • 69 citations

Analysis of Lymphocytes, Monocytes, and Neutrophils from Human Immunodeficiency Virus (HIV)-Infected Persons for HIV DNA

1990 • 67 citations

HIV-1 in Blood Monocytes: Frequency of Detection of Proviral DNA Using PCR and Comparison with the Total CD4 Count

1992 • 61 citations

CD4+ T-Lymphocyte Measures in the Treatment of Individuals Infected With Human Immunodeficiency Virus Type 1

1994 • 50 citations

Single cell transcript analysis of human immunodeficiency virus gene expression in the transition from latent to productive infection

1995 • 44 citations

Detection of CD4+ T cells harboring human immunodeficiency virus type 1 DNA by flow cytometry using simultaneous immunophenotyping and PCR-driven in situ hybridization: evidence of epitope masking of the CD4 cell surface molecule in vivo

1995 • 34 citations

In situ hybridization in suspension and flow cytometry as a tool for the study of gene expression

1992 • 29 citations

Flow cytometric detection of β-globin mRNA in murine haemopoietic tissues using fluorescent in situ hybridization

1990 • 25 citations

Quantification of human immunodeficiency virus type 1-infected mononuclear cells in peripheral blood of seropositive subjects by newly developed flow cytometry analysis of the product of an in situ PCR assay

1994 • 22 citations

Detection of HIV-1 DNA in cells and tissue by fluorescent in situ 5'- nuclease assay (FISNA)

1996 • 20 citations

Correlation between Changes in Plasma HIV RNA Levels and in Plasma Infectivity in Response to Antiretroviral Therapy

1997 • 18 citations

Interaction with Human Immunodeficiency Virus Type 1 Modulates Innate Effector Functions of Human Monocytes

1995 • 10 citations

Immunoglobulin VH usage analysis by fluorescent in situ hybridization and flow cytometry

1992 • 7 citations