Pre-obese and obese agouti mice are sensitive to the anorectic effects of peptide YY3–36 but resistant to ghrelin

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Targeted Disruption of the Melanocortin-4 Receptor Results in Obesity in Mice

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Gut hormone PYY3-36 physiologically inhibits food intake

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1997 • 1,891 citations

Antagonism of Central Melanocortin Receptors in Vitro and in Vivo by Agouti-Related Protein

1997 • 1,835 citations

Inhibition of Food Intake in Obese Subjects by Peptide YY_3–36

2003 • 1,549 citations

The Novel Hypothalamic Peptide Ghrelin Stimulates Food Intake and Growth Hormone Secretion

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Plasma Ghrelin Levels in Lean and Obese Humans and the Effect of Glucose on Ghrelin Secretion

2002 • 1,246 citations

Coexpression of Agrp and NPY in fasting-activated hypothalamic neurons

1998 • 1,136 citations

Ghrelin Causes Hyperphagia and Obesity in Rats

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Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor

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Physiological response to long-term peripheral and central leptin infusion in lean and obese mice

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Ghrelin, an Endogenous Growth Hormone Secretagogue, Is a Novel Orexigenic Peptide That Antagonizes Leptin Action Through the Activation of Hypothalamic Neuropeptide Y/Y1 Receptor Pathway

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Serum Ghrelin Levels Are Inversely Correlated with Body Mass Index, Age, and Insulin Concentrations in Normal Children and Are Markedly Increased in Prader-Willi Syndrome

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Systemic Administration of Ghrelin Induces Fos and Egr‐1 Proteins in the Hypothalamic Arcuate Nucleus of Fasted and Fed Rats

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Ectopic expression of the agouti gene in transgenic mice causes obesity, features of type II diabetes, and yellow fur.

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2000 • 46 citations

A transgenic mouse assay for agouti protein activity.

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Effects of a potent melanocortin agonist on the diabetic/obese phenotype in yellow mice

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Hyperleptinemia in A^y/a mice upregulates arcuate cocaine- and amphetamine-regulated transcript expression

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Leptin responsiveness in mice that ectopically express agouti protein

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