Back to search

Inhibitors of dipeptidyl peptidase IV (DP IV, CD26) induces secretion of transforming growth factor-β1 (TGF-β1) in stimulated mouse splenocytes and thymocytes

Data up to Jan 2025

Published1997
Citations62
References35

Total Citations Per Year

Abstract

References (35)

Direct Association of Adenosine Deaminase with a T Cell Activation Antigen, CD26

1993 • 493 citations

Inflammatory and immunomodulatory roles of TGF-β

1989 • 450 citations

Transforming growth factor-beta is a potent immunosuppressive agent that inhibits IL-1-dependent lymphocyte proliferation.

1988 • 392 citations

Coassociation of CD26 (dipeptidyl peptidase IV) with CD45 on the surface of human T lymphocytes.

1991 • 208 citations

Human CD4 helper T cell activation: functional involvement of two distinct collagen receptors, 1F7 and VLA integrin family.

1990 • 177 citations

The T cell triggering molecule Tp103 is associated with dipeptidyl aminopeptidase IV activity.

1990 • 171 citations

Inhibition of dipeptidyl aminopeptidase IV (DP-IV) by Xaa-boroPro dipeptides and use of these inhibitors to examine the role of DP-IV in T-cell function.

1991 • 169 citations

Transforming growth factor-beta 1 (TGF-beta 1) and recombinant human tumor necrosis factor-alpha reciprocally regulate the generation of lymphokine-activated killer cell activity. Comparison between natural porcine platelet-derived TGF-beta 1 and TGF-beta 2, and recombinant human TGF-beta 1.

1988 • 168 citations

1F7, a novel cell surface molecule, involved in helper function of CD4 cells.

1989 • 152 citations

Comitogenic effect of solid-phase immobilized anti-1F7 on human CD4 T cell activation via CD3 and CD2 pathways.

1990 • 145 citations

The role of dipeptidyl peptidase IV in human T lymphocyte activation. Inhibitors and antibodies against dipeptidyl peptidase IV suppress lymphocyte proliferation and immunoglobulin synthesis in vitro

1987 • 141 citations

Cell surface modulation of CD26 by anti-1F7 monoclonal antibody. Analysis of surface expression and human T cell activation.

1990 • 128 citations

Involvement of Plasma Membrane Dipeptidyl Peptidase IV in Fibronectin-Mediated Adhesion of Cells on Collagen

1985 • 124 citations

CD26 Antigen is a Surface Dipeptidyl Peptidase IV (DPPIV) as Characterized by Monoclonal Antibodies Clone Til‐19‐4‐7 and 4EL1C7

1990 • 118 citations

A Novel Form of Dipeptidylpeptidase IV Found in Human Serum.

1995 • 118 citations

Improved sandwich enzyme-linked immunosorbent assays for transforming growth factor β1

1993 • 112 citations

Direct evidence for the binding of rat liver DPP IV to collagen in vitro

1988 • 112 citations

Functional role of CD26 on human B lymphocytes

1995 • 108 citations

Dipeptidyl Peptidase IV in the Immune System. Effects of Specific Enzyme Inhibitors on Activity of Dipeptidyl Peptidase IV and Proliferation of Human Lymphocytes

1991 • 107 citations

Dipeptidyl Peptidase IV in Human T Lymphocytes

1989 • 100 citations

Transforming growth factor-beta and suppression of humoral immune responses in HIV infection.

1991 • 84 citations

Dipeptidyl peptidase IV of human lymphocytes. Evidence for specific hydrolysis of glycylproline p-nitroanilide in T-lymphocytes

1984 • 82 citations

1F7 (CD26): a marker of thymic maturation involved in the differential regulation of the CD3 and CD2 pathways of human thymocyte activation.

1991 • 80 citations

Regulation of interleukin-2 and interleukin-6 production from T-cells: Involvement of interleukin-1 β and transforming growth factor-β

1990 • 78 citations

Biochemical characterization of CD26 (dipeptidyl peptidase IV): Functional comparison of distinct epitopes recognized by various anti-CD26 monoclonal antibodies

1992 • 75 citations

Dipeptidyl Peptidase IV (CD26) on Human Lymphocytes. Synthetic Inhibitors of and Antibodies against Dipeptidyl Peptidase IV Suppress the Proliferation of Pokeweed Mitogen-Stimulated Peripheral Blood Mononuclear Cells, and IL-2 and IL-6 Production

1993 • 65 citations

Evidence that thymocyte-activating molecule is mouse CD26 (dipeptidyl peptidase IV).

1991 • 63 citations

Inhibitors of Dipeptidyl Peptidase IV (DP IV, CD26) Specifically Suppress Proliferation and Modulate Cytokine Production of Strongly CD26 Expressing U937 Cells

1994 • 60 citations

Transforming growth factor-β1 (TGF-β1) inhibits DNA synthesis of PWM-stimulated PBMC via suppression of IL-2 and IL-6 production

1994 • 45 citations

Triggering of cytotoxic T lymphocytes and NK cells via the Tp103 pathway is dependent on the expression of the T cell receptor/CD3 complex.

1988 • 43 citations

The cytoplasmic tail of the T cell receptor ζ chain is required for signaling via CD26

1995 • 42 citations

Extended Investigation of the Substrate Specificity of Dipeptidyl Peptidase IV from Pig Kidney

1991 • 38 citations

Function of Dipeptidyl Peptidase IV (CD26, Tp103) in Transfected Human T Cells

1993 • 33 citations

Transforming Growth Factor β1Inhibits Interleukin-10 mRNA Expression and Production in Pokeweed Mitogen-Stimulated Peripheral Blood Mononuclear Cells and T Cells

1995 • 27 citations

Induction of interleukin 2 (IL2) and interferon‐γ and enhancement of IL2 receptor expression by a CD26 monoclonal antibody

1991 • 24 citations

Cited By (0)

Loading...