Transforming growth factor-beta and suppression of humoral immune responses in HIV infection.

Abnormalities of B-Cell Activation and Immunoregulation in Patients with the Acquired Immunodeficiency Syndrome

1983 • 1,625 citations

The Human Immunodeficiency Virus: Infectivity and Mechanisms of Pathogenesis

1988 • 1,496 citations

REVERSIBILITY OF LYMPHOMAS AND LYMPHOPROLIFERATIVE LESIONS DEVELOPING UNDER CYCLOSPORIN-STEROID THERAPY

1984 • 1,284 citations

Non-Hodgkin's Lymphoma in 90 Homosexual Men

1984 • 975 citations

Proteolytic activation of latent transforming growth factor-beta from fibroblast-conditioned medium.

1988 • 962 citations

The essential role of B cell stimulatory factor 2 (BSF-2/IL-6) for the terminal differentiation of B cells.

1988 • 791 citations

Growth Inhibitor from BSC-1 Cells Closely Related to Platelet Type β Transforming Growth Factor

1984 • 779 citations

Transforming growth factor beta is an important immunomodulatory protein for human B lymphocytes.

1986 • 777 citations

IgG1 plasmacytosis in interleukin 6 transgenic mice.

1989 • 597 citations

Infection with HIV is associated with elevated IL-6 levels and production.

1990 • 594 citations

B cell stimulating factor 2/interleukin 6 is a costimulant for human thymocytes and T lymphocytes.

1988 • 537 citations

Inhibition of cytotoxic T cell development by transforming growth factor beta and reversal by recombinant tumor necrosis factor alpha.

1987 • 497 citations

Interleukins and IgA synthesis. Human and murine interleukin 6 induce high rate IgA secretion in IgA-committed B cells.

1989 • 444 citations

Latent transforming growth factor-beta in serum. A specific complex with alpha 2-macroglobulin.

1987 • 434 citations

Transforming growth factor-beta is a potent immunosuppressive agent that inhibits IL-1-dependent lymphocyte proliferation.

1988 • 392 citations

Defective Regulation of Epstein–Barr Virus Infection in Patients with Acquired Immunodeficiency Syndrome (AIDS) or AIDS-Related Disorders

1986 • 384 citations

Induction of IL-6 (B cell stimulatory factor-2/IFN-beta 2) production by HIV.

1989 • 314 citations

AIDS — An Immunologic Reevaluation

1984 • 286 citations

Mechanisms of B cell activation in patients with acquired immunodeficiency syndrome and related disorders. Contribution of antibody-producing B cells, of Epstein-Barr virus-infected B cells, and of immunoglobulin production induced by human T cell lymphotropic virus, type III/lymphadenopathy-associated virus.

1986 • 229 citations

Human transforming growth factor type .beta.2: production by a prostatic adenocarcinoma cell line, purification, and initial characterization

1987 • 204 citations

Separate signals for human B cell proliferation and differentiation in response to Staphylococcus aureus: evidence for a two-signal model of B cell activation.

1982 • 200 citations

Transforming growth factor beta and noncytopathic mechanisms of immunodeficiency in human immunodeficiency virus infection.

1990 • 194 citations

Mechanism for transforming growth factor beta and IL-2 enhancement of IgA expression in lipopolysaccharide-stimulated B cell cultures.

1990 • 183 citations

Epstein-Barr virus induces aggressive lymphoproliferative disorders of human B cell origin in SCID/hu chimeric mice.

1990 • 165 citations

Defective B-Lymphocyte Function in Homosexual Men in Relation to the Acquired Immunodeficiency Syndrome

1984 • 146 citations

Beta transforming growth factors are potential regulators of B lymphopoiesis.

1987 • 145 citations

Impaired anti-pneumococcal antibody response in patients with AIDS-related persistent generalized lymphadenopathy.

1987 • 140 citations

Transforming growth factor-beta 1 is a costimulator for IgA production.

1990 • 134 citations

Further studies of the role of transforming growth factor-beta in human B cell function.

1989 • 108 citations

Transforming growth factor type β (TGF β) inhibits G1 to S transition, but not activation of human B lymphocytes

1987 • 97 citations

Epstein‐Barr virus mediates a switch in responsiveness to transforming growth factor, type beta, in cells of the B cell lineage

1987 • 55 citations

Antigen-specific and polyclonal B-cell responses in patients with acquired immunodeficiency disease syndrome

1986 • 50 citations

Hypergammaglobulinemia associated with human immunodeficiency virus infection.

1988 • 37 citations

The relationship of serum IgA concentration to human immunodeficiency virus (HIV) infection: A cross-sectional study of HIV-seropositive individuals detected by screening in the United States Air Force

1988 • 36 citations

Abnormal B-cell response to T-cell-independent polyclonal B-cell activators in homosexuals presenting persistent generalized lymph node enlargement and HTLV-III antibodies.

1986 • 15 citations

Increased IgA as a predictor of development of AIDS in HIV-infected subjects.

1988 • 15 citations

Predominance of the IgG1 subclass in the hypergammaglobulinemia observed in pre-AIDS and AIDS.

1988 • 13 citations