1,25(OH)2 vitamin D3, and retinoic acid antagonize endothelin-stimulated hypertrophy of neonatal rat cardiac myocytes.

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Identification of a receptor for the morphogen retinoic acid

1987 • 2,007 citations

Effects of cytochalasin and phalloidin on actin.

1987 • 1,989 citations

Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors

1991 • 1,725 citations

Molecular characterization of angiotensin II--induced hypertrophy of cardiac myocytes and hyperplasia of cardiac fibroblasts. Critical role of the AT1 receptor subtype.

1993 • 1,420 citations

RXRβ: A coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements

1991 • 1,241 citations

Function of the retinoic acid receptors (RARs) during development: (II) Multiple abnormalities at various stages of organogenesis in RAR double mutants

1994 • 987 citations

Cloning and expression of full-length cDNA encoding human vitamin D receptor.

1988 • 961 citations

A novel rapid assay for chloramphenicol acetyltransferase gene expression

1987 • 802 citations

Regulation of cardiac gene expression during myocardial growth and hypertrophy: molecular studies of an adaptive physiologic response

1991 • 798 citations

Genetic analysis of RXRα developmental function: Convergence of RXR and RAR signaling pathways in heart and eye morphogenesis

1994 • 684 citations

Endothelin induction of inositol phospholipid hydrolysis, sarcomere assembly, and cardiac gene expression in ventricular myocytes. A paracrine mechanism for myocardial cell hypertrophy

1990 • 641 citations

RXR alpha mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis.

1994 • 632 citations

Molecular characterization of the stretch-induced adaptation of cultured cardiac cells. An in vitro model of load-induced cardiac hypertrophy.

1992 • 611 citations

Endothelin-1 is an autocrine/paracrine factor in the mechanism of angiotensin II-induced hypertrophy in cultured rat cardiomyocytes.

1993 • 576 citations

Myocyte hypertrophy in neonatal rat heart cultures and its regulation by serum and by catecholamines.

1982 • 428 citations

Renin-angiotensin system involvement in pressure-overload cardiac hypertrophy in rats

1990 • 409 citations

Retinoid X receptor-COUP-TF interactions modulate retinoic acid signaling.

1992 • 389 citations

Endothelin-1 and fibroblast growth factors stimulate the mitogen-activated protein kinase signaling cascade in cardiac myocytes. The potential role of the cascade in the integration of two signaling pathways leading to myocyte hypertrophy.

1994 • 387 citations

Identification and regulation of 1,25-dihydroxyvitamin D3 receptor activity and biosynthesis of 1,25-dihydroxyvitamin D3. Studies in cultured bovine aortic endothelial cells and human dermal capillaries.

1989 • 340 citations

Insulin-like growth factor-1 enhances ventricular hypertrophy and function during the onset of experimental cardiac failure.

1995 • 328 citations

Endothelin ETA receptor antagonist blocks cardiac hypertrophy provoked by hemodynamic overload.

1994 • 252 citations

The cardiac beta-myosin heavy chain isogene is induced selectively in alpha 1-adrenergic receptor-stimulated hypertrophy of cultured rat heart myocytes.

1990 • 200 citations

M-CAT, CArG, and Sp1 Elements Are Required for α1-Adrenergic Induction of the Skeletal α-Actin Promoter during Cardiac Myocyte Hypertrophy

1995 • 181 citations

1,25-dihydroxyvitamin D3 modulates growth of vascular smooth muscle cells.

1991 • 181 citations

Vitamin D3 and cardiovascular function in rats.

1987 • 179 citations

Interaction between retinoic acid and vitamin D signaling pathways.

1993 • 171 citations

Atrial-like phenotype is associated with embryonic ventricular failure in retinoid X receptor alpha -/- mice.

1995 • 166 citations

Involvement of vitamin D3 with cardiovascular function. III. Effects on physical and morphological properties

1990 • 155 citations

Demonstration of 1,25(OH)2 vitamin D3 receptors and actions in vascular smooth muscle cellsIn vitro

1987 • 149 citations

Effects of thyroid hormone on alpha-actin and myosin heavy chain gene expression in cardiac and skeletal muscles of the rat: measurement of mRNA content using synthetic oligonucleotide probes.

1986 • 131 citations

Human and canine gene homologs of porcine brain natriuretic peptide

1989 • 119 citations

1,25-Dihydroxyvitamin D3 receptors identified in the rat heart

1986 • 116 citations

Retinoid-dependent pathways suppress myocardial cell hypertrophy.

1995 • 102 citations

Positive regulation of the skeletal alpha-actin gene by Fos and Jun in cardiac myocytes.

1992 • 86 citations

1,25-Dihydroxyvitamin D3 stimulates 45Ca2+ uptake by cultured adult rat ventricular cardiac muscle cells.

1987 • 85 citations

Endothelin-1 and its binding sites are upregulated in pressure overload cardiac hypertrophy

1995 • 85 citations

Brain natriuretic peptide as a marker for hypertensive left ventricular hypertrophy: Changes during 1-year antihypertensive therapy with angiotensin-converting enzyme inhibitor

1995 • 82 citations

Contractile activity modulates actin synthesis and turnover in cultured neonatal rat heart cells.

1993 • 73 citations

Propagation of mouse mammary tumor cell lines and production of mouse mammary tumor virus in a serum-free medium

1976 • 71 citations

Divergent Regulation of the Human Atrial Natriuretic Peptide Gene by c-jun and c-fos

1992 • 68 citations

Negative regulation of the human atrial natriuretic peptide gene by 1,25-dihydroxyvitamin D3.

1994 • 58 citations

The Involvement of the Endocrine System in Regulating Cardiovascular Function: Emphasis on Vitamin D₃*

1989 • 57 citations

1,25(OH)2D3 suppresses expression and secretion of atrial natriuretic peptide from cardiac myocytes

1995 • 53 citations

Divergent regulation of the human atrial natriuretic peptide gene by c-jun and c-fos.

1992 • 51 citations

Tissue-specific Determinants of Human Atrial Natriuretic Factor Gene Expression in Cardiac Tissue

1989 • 49 citations

Perinatal expression of the atrial natriuretic factor gene in rat cardiac tissue

1988 • 39 citations

Phorbol ester stimulates the synthesis and secretion of brain natriuretic peptide from neonatal rat ventricular cardiocytes: a comparison with the regulation of atrial natriuretic factor.

1993 • 38 citations

Regulation of myosin isozyme expression by vitamin D3 deficiency and 1,25-dihydroxyvitamin D3 in the rat heart.

1994 • 37 citations

22-Oxacalcitriol: dissection of 1,25(OH)2D3 receptor-mediated and Ca2+ entry-stimulating pathways

1993 • 35 citations

Cis-Active Determinants of Cardiac-Specific Expression in the Human Atrial Natriuretic Peptide Gene

1991 • 35 citations

The discovery of 9-cis retinoic acid a hormone that binds the retinoid-X receptor

1994 • 31 citations

Phorbol ester stimulates the synthesis and secretion of brain natriuretic peptide from neonatal rat ventricular cardiocytes: a comparison with the regulation of atrial natriuretic factor

1993 • 11 citations

Regulation of myosin isozyme expression by vitamin D3 deficiency and 1,25-dihydroxyvitamin D3 in the rat heart

1994 • 10 citations