Regulation of Gonadotropin-Releasing Hormone (GnRH) Gene Expression by 5α-Dihydrotestosterone in GnRH-Secreting GT1–7 Hypothalamic Neurons¹

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1984 • 4,899 citations

Evidence of Estrogen Receptors in Normal Human Osteoblast-Like Cells

1988 • 1,246 citations

Isolation and Characterization of Full-Length cDNA Clones for Human α-, β-, and γ-Actin mRNAs: Skeletal but Not Cytoplasmic Actins Have an Amino-Terminal Cysteine that Is Subsequently Removed

1983 • 1,220 citations

Immortalization of hypothalamic GnRH by genetically targeted tumorigenesis

1990 • 959 citations

Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells.

1996 • 627 citations

Absence of oestradiol concentration in cell nuclei of LHRH-immunoreactive neurones

1983 • 526 citations

High efficiency gene transfer into mammalian cells

1984 • 498 citations

Isolation of the gene and hypothalamic cDNA for the common precursor of gonadotropin-releasing hormone and prolactin release-inhibiting factor in human and rat.

1986 • 353 citations

The human androgen receptor: Domain structure, genomic organization and regulation of expression

1989 • 334 citations

The hormone response element of the mouse mammary tumour virus DNA mediates the progestin and androgen induction of transcription in the proviral long terminal repeat region.

1987 • 275 citations

Localization of oestrogen receptors in preoptic neurons containing neurotensin but not tyrosine hydroxylase, cholecystokinin or luteinizing hormone-releasing hormone in the male and female rat

1992 • 273 citations

Steroids Modulate Corticotropin-Releasing Hormone Production in Human Fetal Membranes and Placenta*

1989 • 264 citations

Regulation of transcription by cyclic AMP-dependent protein kinase.

1989 • 247 citations

Do gonadotropin-releasing hormone, tyrosine hydroxylase-, and beta-endorphin-immunoreactive neurons contain estrogen receptors? A double-label immunocytochemical study in the Suffolk ewe.

1993 • 243 citations

Androgen receptor gene expression in human prostate carcinoma cell lines.

1990 • 220 citations

Androgen-dependent cell cycle arrest and apoptotic death in PC-3 prostatic cell cultures expressing a full-length human androgen receptor

1997 • 167 citations

Transcriptional and posttranscriptional regulation of human androgen receptor expression by androgen.

1993 • 151 citations

Regulation of Gonadotropin-Releasing Hormone Gene Expressionin Vivoandin Vitro

1997 • 138 citations

Biology of Normal Luteinizing Hormone-Releasing Hormone Neurons During and After Their Migration from Olfactory Placode

1992 • 113 citations

Immunocytochemical detection of androgen receptor in human temporal cortex: Characterization and application of polyclonal androgen receptor antibodies in frozen and paraffin-embedded tissues

1995 • 108 citations

Regulation of Pro-Gonadotropin-Releasing Hormone Gene Expression by Sex Steroids in The Brain of Male and Female Rats

1989 • 103 citations

Absence of androgen receptors in LHRH immunoreactive neurons

1993 • 102 citations

Identification of estrogen-responsive LHRH Neurons in the guinea pig hypothalamus

1984 • 92 citations

Immortalized hypothalamic luteinizing hormone-releasing hormone (LHRH) neurons: A new tool for dissecting the molecular and cellular basis of LHRH physiology

1995 • 87 citations

Transcriptional and posttranscriptional regulation of human androgen receptor expression by androgen

1993 • 85 citations

Further Evidence that Most Luteinizing Hormone‐Releasing Hormone Neurons are not Directly Estrogen‐Responsive: Simultaneous Localization of Luteinizing Hormone‐Releasing Hormone and Estrogen Receptor Immunoreactivity in the Guinea‐Pig Brain

1992 • 81 citations

Steroid binding and metabolism in the luteinizing hormone-releasing hormone-producing neuronal cell line GT1-1.

1994 • 79 citations

NMDA and nitric oxide act through the cGMP signal transduction pathway to repress hypothalamic gonadotropin-releasing hormone gene expression.

1996 • 78 citations

Transmitter Content and Afferent Connections of Estrogen-Sensitive Progestin Receptor-Containing Neurons in the Primate Hypothalamus

1992 • 72 citations

Do Testosterone and Estradiol-17β Enforce Inhibition or Stimulation of Luteinizing Hormone-Releasing Hormone Secretion?1

1989 • 66 citations

A Subgroup of LHRH Neurons in Guinea Pigs with Progestin Receptors Is Centrally Positioned within the Total Population of LHRH Neurons

1995 • 65 citations

Cross-talk between excitatory and inhibitory amino acids in the regulation of luteinizing hormone-releasing hormone secretion.

1992 • 64 citations

Single Cell Levels of Hypothalamic Messenger Ribonucleic Acid Encoding Luteinizing Hormone Releasing Hormone in Intact, Castrated, and Hyperprolactinemic Male Rats*

1991 • 62 citations

Luteinizing Hormone‐Releasing Hormone and Gamma‐Aminobutyric Acid Neurons in the Medial Preoptic Area are Synaptic Targets of Dopamine Axons Originating in Anterior Periventricular Areas

1993 • 56 citations

Regulation of preoptic area gonadotrophin-releasing hormone (GnRH) mRNA expression by gonadal steroids in the long-term gonadectomized male rat

1997 • 53 citations

Progestin receptor-containing cells in guinea pig hypothalamus: Afferent connections, morphological characteristics, and neurotransmitter content

1990 • 52 citations

Gonadotropin-Releasing Hormone Messenger Ribonucleic Acid Levels Are Unaltered with Changes in the Gonadal Hormone Milieu of the Adult Male Rat*

1990 • 50 citations

Testosterone stimulates LH-RH-like mRNA level in the rat hypothalamus

1988 • 50 citations

Gonadotropin‐releasing hormone mRNA in the rat: Distribution and neuronal content over the estrous cycle and after castration of males

1991 • 49 citations

Molecular Aspects of the Interaction between Estrogen and the Membrane Excitability of Hypothalamic Nerve Cells

1984 • 48 citations

Pulsatile Luteinizing Hormone (LH) Patterns in Ovariectomized Rats: Involvement of Norepinephrine and Dopamine in the Release of LH-Releasing Hormone and LH*

1982 • 46 citations

Steroid binding and metabolism in the luteinizing hormone-releasing hormone-producing neuronal cell line GT1-1

1994 • 45 citations

Regulation of gonadotropin-releasing hormone (GnRH) gene expression in hypothalamic neuronal cells

1995 • 40 citations

The Mouse Androgen Receptor Gene Contains a Second Functional Promoter Which Is Regulated by Dihydrotestosterone

1994 • 29 citations

Neural Control of the Synthesis and Release of Luteinizing Hormone‐Releasing Hormone

2007 • 29 citations

Steroidal modulation of the regulatory neuropeptides: Luteinizing hormone releasing hormone, neuropeptide y and endogenous opioid peptides

1986 • 29 citations

Cross-talk between excitatory and inhibitory amino acids in the regulation of luteinizing hormone-releasing hormone secretion

1992 • 21 citations

Effects of dehydroepiandrosterone (DHEA) on GnRH gene expression in the rat brain as studied by in situ hybridization

1995 • 18 citations

Opioid Inhibition of Adrenergic and Dopaminergic but Not Serotonergic Stimulation of Luteinizing Hormone Releasing Hormone Release from Immortalized Hypothalamic Neurons

1994 • 13 citations

Involvement of an autoregulatory mechanism for the regulation of gonadotropin-releasing hormone (GnRH) gene expression in neurons in the rat preoptic area

1994 • 7 citations

Neuroendocrine Control of Reproduction

1995 • 6 citations

Biology of normal luteinizing hormone-releasing hormone neurons during and after their migration from olfactory placode

1992 • 6 citations