Distinct genetic loci control development of benign and malignant skin tumours in mice

MAPMAKER: An interactive computer package for constructing primary genetic linkage maps of experimental and natural populations

1987 • 6,762 citations

Genetic Dissection of Complex Traits

1994 • 3,497 citations

Resolution of quantitative traits into Mendelian factors by using a complete linkage map of restriction fragment length polymorphisms

1988 • 1,513 citations

A genetic map of the mouse suitable for typing intraspecific crosses.

1992 • 1,114 citations

Theoretical basis for separation of multiple linked gene effects in mapping quantitative trait loci.

1993 • 1,112 citations

Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis

1986 • 865 citations

Antioncogenes and human cancer.

1993 • 772 citations

Scatter factor: molecular characteristics and effect on the invasiveness of epithelial cells.

1990 • 695 citations

Genetic analysis of autoimmune type 1 diabetes mellitus in mice

1991 • 494 citations

Towards construction of a high resolution map of the mouse genome using PCR-analysed microsatellites

1990 • 475 citations

Allelic loss of chromosomes 16q and 10q in human prostate cancer.

1990 • 456 citations

Regressive Logistic Models for Familial Disease and Other Binary Traits

1986 • 381 citations

Polygenic control of autoimmune diabetes in nonobese diabetic mice

1993 • 298 citations

An Association between the Risk of Cancer and Mutations in the HRAS1 Minisatellite Locus

1993 • 290 citations

Genetic changes in skin tumor progression: Correlation between presence of a mutant ras gene and loss of heterozygosity on mouse chromosome 7

1990 • 270 citations

The pathogenesis of squamous cell cancer: lessons learned from studies of skin carcinogenesis--thirty-third G. H. A. Clowes Memorial Award Lecture.

1994 • 248 citations

Keratinocyte growth factor functions in epithelial induction during seminal vesicle development.

1994 • 187 citations

Additional microsatellite markers for mouse genome mapping

1991 • 158 citations

Genetic control of hepatocarcinogenesis in C57BL/6J and C3H/HeJ inbred mice

1986 • 152 citations

The generation of a library of PCR-analyzed microsatellite variants for genetic mapping of the mouse genome

1991 • 143 citations

Loss of heterozygosity and mutational alterations of the p53 gene in skin tumours of interspecific hybrid mice.

1991 • 139 citations

Induction of papillomas with a high probability of conversion to malignancy

1985 • 132 citations

A major susceptibility locus to murine lung carcinogenesis maps on chromosome 6

1993 • 128 citations

Inherited predisposition to cancer

1990 • 128 citations

Transgenic overexpression of transforming growth factor alpha bypasses the need for c-Ha-ras mutations in mouse skin tumorigenesis.

1992 • 107 citations

Cancer Incidence in Defined Populations

1980 • 100 citations

Nonrandom duplication of the chromosome bearing a mutated Ha-ras-1 allele in mouse skin tumors.

1990 • 98 citations

Sequential trisomization of chromosomes 6 and 7 in mouse skin premalignant lesions

1989 • 96 citations

KRAS2 as a genetic marker for lung tumor susceptibility in inbred mice

1989 • 95 citations

Multiple Loci Affect Genetic Predisposition to Hepatocarcinogenesis in Mice

1994 • 94 citations

Chromosome mapping of murine susceptibility loci to liver carcinogenesis.

1993 • 92 citations

Genetic mapping of tumor susceptibility genes involved in mouse plasmacytomagenesis.

1993 • 91 citations

The recombinant congenic strains for analysis of multigenic traits: genetic composition

1992 • 88 citations

The second intron of the K-ras gene containsregulatory elements associated with mouse lung tumorsusceptibility.

1994 • 86 citations

Developmentally regulated expression of an exon containing a stop codon in the gene for glutamic acid decarboxylase.

1990 • 85 citations

An Association Between the Risk of Cancer and Mutations in the HRAS1 Minisatellite Locus

1994 • 65 citations

The pharmacogenetics of chemical carcinogenesis

1992 • 64 citations

Characterization of an inbred strain of the SENCAR mouse that is highly sensitive to phorbol esters

1987 • 56 citations

Mouse Chromosome 7

1992 • 53 citations

Multistage carcinogenesis

2004 • 47 citations

Allelotype analysis of mouse skin tumors using polymorphic microsatellites: sequential genetic alterations on chromosomes 6, 7, and 11.

1993 • 45 citations

Genetics of chemical carcinogenesis. 1. Bidirectional selective breeding of susceptible and resistant lines of mice to two-stage skin carcinogenesis

1990 • 45 citations

Susceptibility to phorbol ester skin tumor promotion in (C57BL/6×DBA/2) F₁ mice is inherited as an incomplete dominant trait: evidence for multi-locus involvement

1988 • 45 citations

Genetic resolution of susceptibility to cancer--new perspectives.

1992 • 40 citations

Epidermal growth factor receptor ligands regulate keratin 8 expression in keratinocytes, and transforming growth factor alpha mediates the induction of keratin 8 by the v-rasHa oncogene.

1993 • 36 citations

Dissociation of sensitivities to tumor promotion and progression in outbred and inbred SENCAR mice.

1992 • 34 citations

Induction of different genetic changes by different classes of chemical carcinogens during progression of mouse skin tumors

1994 • 28 citations

Transgenic Approaches to the Analysis of ras and p53 Function in Multistage Carcinogenesis

1994 • 19 citations

Structure, Genetic Mapping, and Expression of the MouseHgf/scatter factor Gene

1993 • 8 citations

Predisposition to Cancer

1953 • 5 citations