Epidermal growth factor receptor ligands regulate keratin 8 expression in keratinocytes, and transforming growth factor alpha mediates the induction of keratin 8 by the v-rasHa oncogene.

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

The catalog of human cytokeratins: Patterns of expression in normal epithelia, tumors and cultured cells

1982 • 5,272 citations

Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family

1985 • 2,145 citations

Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus

1983 • 1,857 citations

Calcium regulation of growth and differentiation of mouse epidermal cells in culture

1980 • 1,810 citations

Classification of human epithelia and their neoplasms using monoclonal antibodies to keratins: strategies, applications, and limitations.

1985 • 735 citations

Patterns of expression of murine Vgr-1 and BMP-2a RNA suggest that transforming growth factor-beta-like genes coordinately regulate aspects of embryonic development.

1989 • 440 citations

Isolation and properties of Moloney murine leukemia virus mutants: use of a rapid assay for release of virion reverse transcriptase

1981 • 439 citations

Reversible staining and peptide mapping of proteins transferred to nitrocellulose after separation by sodium dodecylsulfate-polyacrylamide gel electrophoresis

1986 • 408 citations

Transgenic mice provide new insights into the role of TGF-alpha during epidermal development and differentiation.

1991 • 407 citations

Formation of cytoskeletal elements during mouse embryogenesis. IV. Ultrastructure of primary mesenchymal cells and their cell-cell interactions.

1983 • 320 citations

Expression of epidermal keratins and filaggrin during human fetal skin development.

1985 • 284 citations

Skin hyperkeratosis and papilloma formation in transgenic mice expressing a ras oncogene from a suprabasal keratin promoter

1990 • 277 citations

Accumulation of p21ras.GTP in response to stimulation with epidermal growth factor and oncogene products with tyrosine kinase activity.

1990 • 264 citations

Identification of Merkel cells in human skin by specific cytokeratin antibodies:

1984 • 246 citations

Changes in the Pattern of Cytokeratin Polypeptides in Epidermis and Hair Follicles During Skin Development in Human Fetuses

1982 • 230 citations

An activated Harvey ras oncogene produces benign tumours on mouse epidermal tissue

1986 • 218 citations

Cytokine involvement in oocytes and early embryos

1991 • 206 citations

Regulated expression of differentiation-associated keratins in cultured epidermal cells detected by monospecific antibodies to unique peptides of mouse epidermal keratins

1987 • 187 citations

Synthetic peptides corresponding to keratin subunits elicit highly specific antibodies.

1984 • 186 citations

Development of murine epidermal cell lines which contain an activated rasHa oncogene and form papillomas in skin grafts on athymic nude mouse hosts.

1988 • 183 citations

Transcriptional control of high molecular weight keratin gene expression in multistage mouse skin carcinogenesis.

1988 • 182 citations

Expression of simple epithelial type cytokeratins in stratified epithelia as detected by immunolocalization and hybridization in situ.

1988 • 168 citations

Spontaneous losses of control of cytokeratin gene expression in transformed, non-epithelial human cells occurring at different levels of regulation

1989 • 167 citations

Activation of an intron enhancer within the keratin 18 gene by expression of c-fos and c-jun in undifferentiated F9 embryonal carcinoma cells.

1990 • 153 citations

Low level expression of cytokeratins 8, 18 and 19 in vascular smooth muscle cells of human umbilical cord and in cultured cells derived therefrom, with an analysis of the chromosomal locus containing the cytokeratin 19 gene.

1988 • 141 citations

TGF-beta and retinoic acid: regulators of growth and modifiers of differentiation in human epidermal cells.

1990 • 129 citations

Cytokeratin expression in simple epithelia

1986 • 124 citations

Transforming growth factor-alpha expression is enhanced in human mammary epithelial cells transformed by an activated c-Ha-ras protooncogene but not by the c-neu protooncogene, and overexpression of the transforming growth factor-alpha complementary DNA leads to transformation.

1990 • 109 citations

Expression of Simple Epithelial Keratins 8 and 18 in Epidermal Neoplasia

1991 • 107 citations

Transgenic overexpression of transforming growth factor alpha bypasses the need for c-Ha-ras mutations in mouse skin tumorigenesis.

1992 • 107 citations

Transient coexpression of desmin and cytokeratins 8 and 18 in developing myocardial cells of some vertebrate species

1988 • 103 citations

Induction and Autocrine Receptor Binding of Transforming Growth Factor-β2 during Terminal Differentiation of Primary Mouse Keratinocytes

1990 • 81 citations

Extracellular matrix receptors and mouse skin carcinogenesis: altered expression linked to appearance of early markers of tumor progression.

1992 • 76 citations

Activation of the autocrine transforming growth factor alpha pathway in human squamous carcinoma cells.

1991 • 74 citations

Expression of simple epithelial cytokeratins in mouse epidermal keratinocytes harboring Harvey ras gene alterations.

1992 • 74 citations

TGFα stimulates growth of skin papillomas by autocrine and paracrine mechanisms but does not cause neoplastic progression

1988 • 70 citations

Identification of the gene coding for the Endo B murine cytokeratin and its methylated, stable inactive state in mouse nonepithelial cells.

1988 • 69 citations

The v‐ras oncogene inhibits the expression of differentiation markers and facilitates expression of cytokeratins 8 and 18 in mouse keratinocytes

1990 • 67 citations

Expression of EGF receptor, involucrin, and cytokeratins in basal cell carcinomas and squamous cell, carcinomas of the skin

1989 • 61 citations

Aberrant expression of the simple epithelial type II keratin 8 by mouse skin carcinomas but not papillomas

1992 • 58 citations

Simple epithelial nature of some simian virus-40-transformed human epidermal keratinocytes.

1984 • 54 citations

Reexpression of fetal characters in simian virus 40-transformed human keratinocytes.

1985 • 51 citations

Embryonic simple epithelial keratins 8 and 18: chromosomal location emphasizes difference from other keratin pairs.

1990 • 47 citations

9 The Role of Growth Factors in Embryonic Induction in Amphibians

1990 • 42 citations

Differential distribution of cytokeratins after microinjection of anti-cytokeratin monoclonal antibodies.

1987 • 42 citations

Coexpression of specific acid and basic cytokeratins in teratocarcinoma-derived fibroblasts treated with 5-azacytidine

1985 • 42 citations

Elevated expression of secondary, but not early, responding genes to phorbol ester tumor promoters in papillomas and carcinomas of mouse skin

1990 • 38 citations

Mesenchymal-epithelial conversions induced by 5-Azacytidine: Appearance of cytokeratin Endo-A messenger RNA

1986 • 37 citations

Interaction of epidermal growth factor with basal and differentiating epidermal cells of mice resistant and sensitive to carcinogenesis

1984 • 31 citations

The promoter of the endo A cytokeratin gene is activated by a 3' downstream enhancer

1991 • 28 citations

Chapter 6 Developmental Expression of Human Epidermal Keratins and Filaggrin

1987 • 28 citations

Gene expression of cytokeratin endo A and endo B during embryogenesis and in adult tissues of mouse

1991 • 26 citations

Complete sequence of the mouse type-II keratin EndoA: its amino-terminal region resembles mitochondrial signal peptides

1988 • 25 citations

Analysis of phospholipid metabolism in murine keratinocytes transformed by the v-ras oncogene: relationship of phosphatidylinositol turnover and cytokine stimulation to the transformed phenotype

1992 • 23 citations

Development of an in vitro model to study carcinogen-induced neoplastic progression of initiated mouse epidermal cells.

1992 • 15 citations

Differential regulation of keratin 8 and 18 messenger RNAs in differentiating F9 cells

1990 • 14 citations

Cell Receptors as Mediators of Metabolic Signals

1989 • 1 citations