Chromatin structure and dynamics

Position-independent, high-level expression of the human β-globin gene in transgenic mice

1987 • 1,955 citations

Formation of parallel four-stranded complexes by guanine-rich motifs in DNA and its implications for meiosis

1988 • 1,734 citations

Involvement of histone H1 in the organization of the nucleosome and of the salt-dependent superstructures of chromatin.

1979 • 1,532 citations

The 5′ ends of Drosophila heat shock genes in chromatin are hypersensitive to DNase I

1980 • 1,114 citations

Structure of the nucleosome core particle at 7 Å resolution

1984 • 1,028 citations

brahma: A regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2SWI2

1992 • 951 citations

Telomeric DNA dimerizes by formation of guanine tetrads between hairpin loops

1989 • 939 citations

Sequence periodicities in chicken nucleosome core DNA

1986 • 930 citations

A 5′ element of the chicken β-globin domain serves as an insulator in human erythroid cells and protects against position effect in Drosophila

1993 • 858 citations

Stimulation of GAL4 Derivative Binding to Nucleosomal DNA by the Yeast SWI/SNF Complex

1994 • 853 citations

Nucleosomes are assembled by an acidic protein which binds histones and transfers them to DNA

1978 • 763 citations

Crystal structure of globular domain of histone H5 and its implications for nucleosome binding

1993 • 739 citations

The inactive X chromosome in female mammals is distinguished by a lack of histone H4 acetylation, a cytogenetic marker for gene expression

1993 • 692 citations

ATP-dependent nucleosome disruption at a heat-shock promoter mediated by binding of GAGA transcription factor

1994 • 662 citations

A position-effect assay for boundaries of higher order chromosomal domains

1991 • 616 citations

A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptor.

1993 • 598 citations

A nuclear DNA attachment element mediates elevated and position-independent gene activity

1989 • 597 citations

The Polycomb protein shares a homologous domain with a heterochromatin-associated protein of Drosophila.

1991 • 566 citations

Nucleosome loss activates yeast downstream promoters in vivo

1988 • 456 citations

Isolation of type I and II DNA topoisomerase mutants from fission yeast: single and double mutants show different phenotypes in cell growth and chromatin organization.

1984 • 444 citations

Nucleosome positioning modulates accessibility of regulatory proteins to the mouse mammary tumor virus promoter

1990 • 440 citations

Five SWI/SNF gene products are components of a large multisubunit complex required for transcriptional enhancement.

1994 • 410 citations

A multisubunit complex containing the SWI1/ADR6,SWI2/SNF2, SWI3, SNF5, and SNF6 gene products isolated fromyeast.

1994 • 396 citations

Structure of plectonemically supercoiled DNA

1990 • 391 citations

Role of Nucleosomal Cores and Histone H1 in Regulation of Transcription by RNA Polymerase II

1991 • 379 citations

Transcription factor access is mediated by accurately positioned nucleosomes on the mouse mammary tumor virus promoter.

1991 • 372 citations

Metaphase chromosome structure: Bands arise from a differential folding path of the highly AT-rich scaffold

1994 • 368 citations

Disassembly of the nucleus in mitotic extracts: Membrane vesicularization, lamin disassembly, and chromosome condensation are independent processes

1987 • 349 citations

A Polycomb response element in the Ubx gene that determines an epigenetically inherited state of repression.

1994 • 346 citations

Lampbrush chromosomes of crested newtsTriturus cristatus(Laurenti)

1960 • 343 citations

Topography of the histone octamer surface: repeating structural motifs utilized in the docking of nucleosomal DNA.

1993 • 333 citations

Structural features of a phased nucleosome core particle.

1983 • 323 citations

A sequence motif found in aDrosophilaheterochromatin protein is conserved in animals and plants

1991 • 273 citations

Structure of the B-DNA decamer C-C-A-A-C-G-T-T-G-G and comparison with isomorphous decamers C-C-A-A-G-A-T-T-G-G and C-C-A-G-G-C-C-T-G-G

1991 • 260 citations

The β subunit of Oxytricha telomere-binding protein promotes G-quartet formation by telomeric DNA

1993 • 249 citations

A histone octamer can step around a transcribing polymerase without leaving the template

1994 • 238 citations

A mammalian DNA-binding protein that contains a chromodomain and an SNF2/SWI2-like helicase domain.

1993 • 230 citations

Eukaryotic RNA polymerase II binds to nucleosome cores from transcribed genes

1983 • 224 citations

Structural analysis of a triple complex between the histone octamer, a Xenopus gene for 5S RNA and transcription factor IIIA.

1985 • 222 citations

Short-Range DNA Looping by the Xenopus HMG-Box Transcription Factor, xUBF

1994 • 216 citations

Cell-free system for assembly of transcriptionally repressed chromatin from Drosophila embryos.

1992 • 210 citations

Nucleosomes are positioned with base pair precision adjacent to the alpha 2 operator in Saccharomyces cerevisiae.

1991 • 203 citations

Nuclease digestion of circular TRP1ARS1 chromatin reveals positioned nucleosomes separated by nuclease-sensitive regions

1984 • 196 citations

The bending of DNA in nucleosomes and its wider implications

1987 • 189 citations

Effects of DNA sequence and histone-histone interactions on nucleosome placement

1990 • 188 citations

Chromatin Transitions during Early Xenopus Embryogenesis: Changes in Histone H4 Acetylation and in Linker Histone Type

1993 • 186 citations

The yeast telomere-binding protein RAP1 binds to and promotes the formation of DNA quadruplexes in telomeric DNA.

1994 • 176 citations

DNA chaperones: A solution to a persistence problem?

1994 • 168 citations

Switching gene swi6, involved in repression of silent mating-type loci in fission yeast, encodes a homologue of chromatin-associated proteins from Drosophila and mammals

1994 • 163 citations

Nucleosome disruption at the yeast PHO5 promoter upon PHO5 induction occurs in the absence of DNA replication

1992 • 159 citations

Preferential and asymmetric interaction of linker histones with 5S DNA in the nucleosome.

1993 • 149 citations

HMG-D, the Drosophila melanogaster homologue of HMG 1 protein, is associated with early embryonic chromatin in the absence of histone H1.

1994 • 138 citations

Specific inhibition of DNA Binding to nuclear scaffolds and histone H1 by distamycin

1989 • 137 citations

Histone H1 is located in the interior of the chromatin 30-nm filament

1994 • 121 citations

Footprinting of linker histones H5 and H1 on the nucleosome.

1988 • 116 citations

Thymine dimer formation as a probe of the path of DNA in and between nucleosomes in intact chromatin.

1989 • 102 citations

Asymmetry and polarity of nucleosomes in chicken erythrocyte chromatin.

1989 • 88 citations

Reconstitution experiments show that sequence-specific histone-DNA interactions are the basis for nucleosome phasing on mouse satellite DNA

1985 • 88 citations

Promoter sequence containing (CT)n · (GA)n repeats is critical for the formation of the DNase I hypersensitive sites in the Drosophila hsp26 gene

1992 • 74 citations

Differences in the binding of H1 variants to DNA

1988 • 69 citations

DNA Sequence Organization in Chromatosomes

1994 • 53 citations

High mobility group proteins 14 and 17 can space nucleosomes in vitro

1993 • 34 citations

Can one measure the free energy of binding of the histone octamer to different DNA sequences by salt-dependent reconstitution?

1991 • 31 citations

Neutron scattering studies of chromatosomes

1991 • 28 citations